Search clinical trials for: High-risk MDS

Total 1607 results

Vincerx Pharma, Inc.

Recruiting

Study of VIP943 in Subjects With Advanced CD123+ Hematologic Malignancies

Acute Myeloid Leukemia | B-cell Acute Lymphoblastic Leukemia | High-risk Myelodysplastic Syndrome

United States
Cogent Biosciences, Inc.

Recruiting

(Apex) Bezuclastinib in Patients With Advanced Systemic Mastocytosis

Advanced Systemic Mastocytosis (AdvSM) | SM With an Associated Hematologic Neoplasm (SM-AHN) | Mast Cell Leukemia (MCL) | Aggressive Systemic Mastocytosis (ASM)

United States, Norway, Spain, Australia, Switzerland, Germany, Belgium, Netherlands, Canada, France, United Kingdom, Austria, Italy
Memorial Sloan Kettering Cancer Center

Recruiting

Cord Blood Transplant in Children and Young Adults With Blood Cancers and Non-malignant Disorders

Hemoglobinopathies | AML | MDS | Bone Marrow Failure | ALL | Inherited Metabolic Disorders | HLH | MPD Withou Myelofibrosis | NHL or HL

United States
Ascentage Pharma Group Inc.

Recruiting

A Study of APG-115 Alone or Combined With Azacitidine in Patients With AML, CMML, or MDS

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Chronic Myelomonocytic Leukemia | AML | MDS | CMML | High-risk Myelodysplastic Syndrome

United States
Gruppo Italiano Malattie EMatologiche dell'Adulto

Recruiting

Feasibility of Allogeneic Stem Cell Transplantation in Higher-risk-MDS (ACROBAT) (ACROBAT)

High-risk MDS

Italy
Novartis Pharmaceuticals

Active, not recruiting

HDM201 in Combination With MBG453 or Venetoclax in Patients With Acute Myeloid Leukemia (AML) or High-risk Myelodysplastic Syndrome (MDS)

Acute Myeloid Leukemia (AML) | High-risk Myelodysplastic Syndrome (MDS)

Spain, Singapore, Australia, Germany, Italy, Finland, United States
University of Birmingham
Jazz Pharmaceuticals; Adienne SA; IMPACT (funded by NHS Blood & Transplant, Anthony...

Active, not recruiting

A Trial of Treatments to Assess the Effects on Outcome of Adults With AML and MDS Undergoing Allogeneic SCT (COSI)

Acute Myeloid Leukaemia | High-risk Myelodysplastic Syndrome

United Kingdom
GT Biopharma, Inc.

Terminated

GTB-3550 Tri-Specific Killer Engager (TriKE®) for High Risk Hematological Malignancies

Acute Myelogenous Leukemia | Systemic Mastocytosis | Mast Cell Leukemia | High-risk Myelodysplastic Syndromes

United States
Opna-IO LLC

Completed

A Study of PLX2853 in Relapsed or Refractory Acute Myeloid Leukemia or High Risk Myelodysplastic Syndrome

High-risk Myelodysplastic Syndrome (MDS) | Relapsed Acute Myeloid Leukemia (AML) | Refractory Acute Myeloid Leukemia (AML)

United States
M.D. Anderson Cancer Center
Sunesis Pharmaceuticals

Completed

Study of Vosaroxin and Decitabine in Older Patients With Acute Myeloid Leukemia and High-risk Myelodysplastic Syndrome

Leukemia

United States
M.D. Anderson Cancer Center
Bristol-Myers Squibb

Completed

Study of Idarubicin, Cytarabine, and Nivolumab in Patients With High-Risk Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML)

Acute Myeloid Leukemia | Leukemia | Myelodysplastic Syndrome

United States
M.D. Anderson Cancer Center
Genzyme, a Sanofi Company

Completed

Clofarabine Plus Cytarabine in Patients With Previously Untreated Acute Myeloid Leukemia and High-risk Myelodysplastic Syndrome

Myelodysplastic Syndromes | Leukemia, Myeloid

United States
M.D. Anderson Cancer Center
Millennium: The Takeda Oncology Company

Terminated

Study of MLN9708 as Maintenance Therapy for Patients With Acute Myeloid Leukemia (AML) and High Risk Myelodysplastic Syndrome (MDS) in Remission

Leukemia

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...

Terminated

Reduced-intensity, Related-donor Bone Marrow Transplantation Followed by High-dose Cyclophosphamide for Hematologic Cancers

Lymphoma | Leukemia | Myelodysplastic Syndrome

United States
University of Ulm

Terminated

Trial of Intensive Chemotherapy With or Without Volasertib in Patients With Newly Diagnosed High-Risk Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML)

Acute Myeloid Leukemia (AML) | High-risk Myelodysplastic Syndrome (MDS)

Germany
Sidney Kimmel Comprehensive Cancer Center at Johns...
Genzyme, a Sanofi Company

Terminated

Phase I Dose-Escalation Trial of Clofarabine Followed by Escalating Doses of Fractionated Cyclophosphamide in Children With Relapsed or Refractory Acute Leukemias (POE07-01)

Acute Myeloid Leukemia | Myeloproliferative Disorders | Myelofibrosis | Chronic Myelomonocytic Leukemia | Juvenile Myelomonocytic Leukemia | Acute Leukemia | Myelodysplastic Syndrome | Acute Lymphocytic Leukemia | Acute Promyelocytic Leukemia | Chronic Myelogenous Leukemia

United States, Canada
M.D. Anderson Cancer Center

Completed

A Feasibility Study of Prophylactic White Blood Cell Transfusions

Leukemia

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI); American Stem Cell, Inc.

Completed

Cord Blood Fucosylation to Enhance Homing and Engraftment in Patients With Hematologic Malignancies

Lymphoma | Leukemia | Transplantation Infection | Blood And Marrow Transplantation | Transplantation, Bone Marrow

United States
M.D. Anderson Cancer Center
Merck Sharp & Dohme LLC

Completed

Ondansetron Versus Aprepitant Plus Ondansetron for Emesis

Hematologic Diseases | Myelodysplastic Syndrome | Acute Myelogenous Leukemia | Chronic Myelogenous Leukemia

United States
Threshold Pharmaceuticals

Completed

Study of Hypoxia-Activated Prodrug TH-302 to Treat Advanced Leukemias

Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | Acute Myelogenous Leukemia | Chronic Myelogenous Leukemia | High-risk Myelodysplastic Syndrome | Advanced Myelofibrosis

United States
Bristol-Myers Squibb

Not yet recruiting

Study of BMS-986497 (ORM-6151) in Participants With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome

Acute Myeloid Leukemia | Myelodysplastic Syndrome

United States, Canada
Shanghai Changzheng Hospital
CARsgen Therapeutics Co., Ltd.

Not yet recruiting

Study of CT071 Injection in HRNDMM

High-risk Newly Diagnosed Multiple Myeloma (HRNDMM)
Duke University

Not yet recruiting

RECOVER-SLEEP: Platform Protocol, Appendix_A (Hypersomnia)

Long COVID | Long COVID-19 | Hypersomnia
Duke University

Not yet recruiting

RECOVER-SLEEP: Platform Protocol

Sleep Disturbance | Long COVID | Long COVID-19 | Hypersomnia
Qatar University
Hamad Medical Corporation

Not yet recruiting

Outcomes After Unified Versus Standard GDM Diagnosis (UPDATE-GDM)

Pregnancy | Gestational Diabetes | Diagnosis
Sidney Kimmel Comprehensive Cancer Center at Johns...
Janssen Research & Development, LLC

Not yet recruiting

Darzalex Faspro (Daratumumab and Hyaluronidase-fihj) Before Standard Desensitization and Allogeneic Peripheral Blood Stem Cell Transplantation in Adult Patients at High-risk for Primary Graft Failure Secondary to Donor Specific Antibodies

Lymphoma | Multiple Myeloma | Hodgkin Lymphoma | Myelofibrosis | Non Hodgkin Lymphoma | Chronic Myeloid Leukemia | Hematologic Malignancy | Aplastic Anemia | Myelodysplastic Syndromes (MDS) | Acute Myeloid Leukemia (AML) | Bone Marrow Transplant Rejection | Acute Lymphoblastic Leukemia (ALL), Adult
RemeGen Co., Ltd.

Not yet recruiting

To Evaluate the Safety, Efficacy, and Pharmacokinetics of Intravesical Instiliations of Disitamab Vedotin in Patients With High-risk Non-muscular Invasive Bladder Cancer (NMIBC) That Express HER2

High-risk Non-muscle Invasive Bladder Cancer

China
Apollo Therapeutics Ltd

Not yet recruiting

A Study to Investigate APL-4098 Alone and/or in Combination With Azacitidine in R/R AML and High-Risk MDS

Myelodysplastic Syndrome With Excess Blasts | Acute Myeloid Leukemia, in Relapse | Acute Myeloid Leukemia Refractory | Myelodysplastic Syndrome Acute Myeloid Leukemia
Obstetrics & Gynecology Hospital of Fudan University
Peking Union Medical College Hospital; First Affiliated Hospital of Xinjiang... and other collaborators

Not yet recruiting

Role of Methylation Test Triage in HPV Positive Women (MTTRIHPW)

Precancerous Cervical Lesion

China
Byondis B.V.

Not yet recruiting

Safety, Pharmacokinetics, and Preliminary Efficacy of BYON4413 in Acute Myeloid Leukemia and Myelodysplastic Neoplasms.

Relapsed / Refractory AML | Relapsed / Refractory MDS
Postgraduate Institute of Dental Sciences Rohtak

Not yet recruiting

Pregabalin as an add-on Therapy to Carbamazepine in Trigeminal Neuralgia Patients

Trigeminal Neuralgia

India
Ziauddin University
Universiti Sains Malaysia

Not yet recruiting

An Investigation of the Efficacy of OHEM for Improving Oral Hygiene in Children

Gingivitis | Dental Plaque

Pakistan
Virginia Commonwealth University

Not yet recruiting

Zirconia-based Primary Anterior Crowns With Retention Grooves Versus Without Retention Grooves

Dental Caries | Tooth Decay

United States
Virginia Commonwealth University

Not yet recruiting

Resin Polymer (NuSmile BioFlx) Compared to Stainless Steel Crowns (3M ESPE) for Restoration of Primary Molar Teeth

Dental Caries | Tooth Decay

United States
Kliniken Essen-Mitte

Not yet recruiting

Association of Intraoperative Hemodynamic Characteristics to Postoperative Complications and Mortality (HeCoMo)

High-risk Surgery
Henan University of Traditional Chinese Medicine

Not yet recruiting

Screening for High-risk Chronic Obstructive Pulmonary Disease

High-risk COPD

China
National University Hospital, Singapore

Recruiting

The Immediate Effectiveness of a 3D Intraoral Scanner as an Oral Hygiene Educational Tool (3D scanner)

Periodontal Diseases | Plaque Induced Gingival Disease

Singapore
Dana-Farber Cancer Institute

Not yet recruiting

PediCARE Health Equity Intervention in High-Risk Neuroblastoma

Neuroblastoma | Pediatric Cancer | High-risk Neuroblastoma | Financial Stress | Disparities | Poverty

United States
Ruijin Hospital
Sun Yat-sen University; Shanghai Zhongshan Hospital; RenJi Hospital; Huashan Hospital and other collaborators

Recruiting

A Prospective, Multicenter, and Exploratory Study of CMGV in the Treatment of Recurrent Adult AML and MDS-EB-2/Elder AML

Recurrent Adult Acute Myeloid Leukemia | Myelodysplastic Syndrome | Adult Acute Myeloid Leukemia

China
The Royal College of Surgeons of Edinburgh

Recruiting

Minimally Invasive Ridge Splitting Versus the Conventional Open Flap Technique

Alveolar Bone Loss

Egypt, Germany
St. Jude Children's Research Hospital

Not yet recruiting

CAR T-cell Therapy Directed to CD70 for Pediatric Patients With Hematological Malignancies

Lymphoma | Hematologic Malignancy | MDS | AML, Childhood | ALL, Childhood

United States
Senti Biosciences

Recruiting

SENTI-202: Off-the-shelf Logic Gated CAR NK Cell Therapy in Adults With CD33 and/or FLT3 Blood Cancers Including AML/MDS

AML/MDS | CD33 Expressing Hematological Malignancies | FLT3 Expressing Hematological Malignancies

United States, Australia
Kind Pharmaceuticals LLC

Not yet recruiting

A Study of Efficacy and Safety of AND017 in Patients With Myelodysplastic Syndrome

Myelodysplastic Syndromes
Remix Therapeutics

Recruiting

Study of REM-422 in Patients With AML or Higher Risk MDS

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Acute Myeloid Leukemia Refractory | Higher Risk Myelodysplastic Syndromes

United States
Postgraduate Institute of Dental Sciences Rohtak

Recruiting

Comparison of Retention Characteristics of Immediate vs Delayed Retainer Delivery Using 3D Digital Model Analysis

Relapse

India
Assiut University

Not yet recruiting

Impulse Control Disorder Among Parkinson's Disease Patients

Parkinson's Disease
Cancer Research Antwerp
Bayer; Veracyte, Inc.

Recruiting

Treatment of High-Risk Prostate Cancer Guided by Novel Diagnostic Radio- and Molecular Tracers (THUNDER)

Prostate Cancer

Belgium
King Khalid University

Not yet recruiting

Dietary Impacts on Oral Health in Autistic Children: A Cross-Sectional Analysis (OHIDPAP-CS)

Dental Caries in Children | Autistic Disorder | Dietary Habits
Beijing Anzhen Hospital

Recruiting

Standby Cannulated ECMO for High-Risk Percutaneous Coronary Intervention (ESCORT)

High-risk PCI | ECMO

China
Sunnybrook Health Sciences Centre

Not yet recruiting

OURA Ring Wearable Testing in MDS Patients: a Feasibility and Discovery Pilot Study (OURA MDS)

Myelodysplastic Syndromes | MDS

Canada

Search clinical trials for: High-risk MDS

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