Search clinical trials for: Kuvan responder

Total 4042 results

BioMarin Pharmaceutical

Completed

Kuvan® in Phenylketonuria Patients Less Than 4 Years Old (SPARK)

Phenylketonuria

Italy, Turkey, United Kingdom, Germany, Netherlands, Slovakia, Austria, Belgium, Czechia
Merck KGaA, Darmstadt, Germany
Smerud Medical Research International AS; Merck Serono Norway

Completed

Response to Kuvan® in Subjects With Phenylketonuria (PKU) in a 4 Weeks Testing Period (ENDURE)

Phenylketonuria

Norway
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Vemurafenib and Cobimetinib for the Treatment of Patients With High Risk Differentiated Thyroid Carcinoma With BRAFV600E Mutation

Thyroid Gland Follicular Carcinoma | Thyroid Gland Papillary Carcinoma | Thyroid Gland Oncocytic Carcinoma

United States
University of Washington

Not yet recruiting

Low Dose Mosunetuzumab for the Treatment of Patients With Indolent B-Cell Lymphoma

Ann Arbor Stage II Follicular Lymphoma | Ann Arbor Stage III Follicular Lymphoma | Ann Arbor Stage IV Follicular Lymphoma | Grade 1 Follicular Lymphoma | Grade 2 Follicular Lymphoma | Grade 3a Follicular Lymphoma | Ann Arbor Stage II Marginal Zone Lymphoma | Ann Arbor Stage III Marginal Zone Lymphoma and other conditions

United States
National Cancer Institute (NCI)

Not yet recruiting

Pembrolizumab Plus CA-4948 for the Treatment of Patients With Progressive Metastatic Urothelial Cancer Despite Prior Immunotherapy

Metastatic Urothelial Carcinoma | Unresectable Urothelial Carcinoma
Cardarelli Hospital

Not yet recruiting

NBI for Early Diagnosis of OPMD/OSCC (NBI_Oral)

Oral Squamous Cell Carcinoma | Oral Potentially Malignant Disorder

Italy
Roswell Park Cancer Institute

Not yet recruiting

Tamoxifen and Pegylated Liposomal Doxorubicin for the Treatment of Patients With Metastatic or Inoperable, Locally Advanced Triple Negative Breast Cancer

Anatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IV Breast Cancer AJCC v8 | Metastatic Triple-Negative Breast Carcinoma | Locally Advanced Unresectable Triple-Negative Breast Carcinoma

United States
Karolinska University Hospital
University Hospital, Linkoeping

Recruiting

Responders and Non-responders in the Management of Heart Failure - Significance of Genetic Influence and Identification of Novel Informative Biomarkers (Responders)

Heart Failure | Pathophysiology

Sweden
Clinton Bahler
On Target Laboratories

Not yet recruiting

CYTALUX™for the Intraoperative Imaging of Prostate Cancer

Prostate Cancer

United States
Centrum Clinic IVF Center

Not yet recruiting

BEst Size for Ovulation Triggering in Poseidon 4 Patients (BEST 4 Study) (BEST)

Fertilization | Fertilization in Vitro
Jonsson Comprehensive Cancer Center
Boston Scientific Corporation

Not yet recruiting

Yttrium-90 (Y90) Radioembolization for the Treatment of Early Stage Renal Cell Carcinoma, The RENEGADE Trial

Stage I Renal Cell Cancer | Stage II Renal Cell Cancer

United States
Başakşehir Çam & Sakura City Hospital

Not yet recruiting

Evaluation of Low Flow and Normal Flow Anesthesia Management in Robotic Assisted Laparoscopic Surgeries

Oncology
Tanta University

Recruiting

General Anesthesia Versus Sedation By Dexmedetomidine and Ketamine With Local Infiltration for Percutaneous Transcatheter Closure of Atrial Septal Defect in Pediatric Patients

Atrial Septal Defect | Ketamine | General Anesthesia | Dexmedetomidine | Local Infiltration

Egypt
Seoul National University Hospital

Not yet recruiting

Investigator-initiated Clinical Trial to Observe Conjunctival Goblet Cell Using an Anterior Segment Imaging Device

Ocular Surface Disease
Region Skane
The George Institute for Global Health, Australia

Not yet recruiting

International Care Bundle Evaluation in Cerebral Hemorrhage Research (I-CATCHER)

Stroke | Intraventricular Hemorrhage | Cerebrovascular Disease | Intracerebral Hemorrhage | Intracerebral Haemorrhage

Australia, Sweden
Ankara City Hospital Bilkent

Not yet recruiting

Spinal Or General Anesthesia For Umblical Hernia Surgery

General Anesthesia | Umbilical Hernia | Spinal Aneshtesia
Tongji Hospital

Recruiting

Spinal Versus General Anesthesia on Postoperative Pulmonary Complications

Hip Fractures | Anesthesia | Pulmonary Complication

China
Ohio State University Comprehensive Cancer Center

Not yet recruiting

A Bowel Management Program (Retrograde Rectal Enema) for the Treatment of Low Anterior Resection Syndrome in Rectal Cancer Patients

Low Anterior Resection Syndrome | Rectal Carcinoma

United States
Emory University
National Cancer Institute (NCI)

Not yet recruiting

Gemcitabine, Cisplatin and Nab-Paclitaxel as Neoadjuvant Treatment for Patients With Resectable or Borderline Resectable Pancreatic Cancer

Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Stage I Pancreatic Cancer AJCC v8 | Resectable Pancreatic Adenocarcinoma | Borderline Resectable Pancreatic Ductal Adenocarcinoma

United States
National Cancer Institute (NCI)

Not yet recruiting

Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated Sarcomas

Undifferentiated Pleomorphic Sarcoma | Stage III Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8 | Stage IV Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8
First Affiliated Hospital of Fujian Medical University

Not yet recruiting

FAPI and FDG PET/MRI in Diagnosis and Therapy Prediction of Bladder Cancer

Urinary Bladder Neoplasms
Great Ormond Street Hospital for Children NHS Foundation...

Recruiting

Micro-dosing Indocyanine Green (ICG) in Children

Genitourinary Disease | Perfusion | Fluorescence Imaging | Gastrointestinal Tract Disorders

United Kingdom
Mayo Clinic

Recruiting

NXP800 for the Treatment of Patients With Advanced or Metastatic Cholangiocarcinoma

Stage III Intrahepatic Cholangiocarcinoma AJCC v8 | Metastatic Cholangiocarcinoma | Refractory Cholangiocarcinoma | Stage III Hilar Cholangiocarcinoma AJCC v8 | Stage IV Hilar Cholangiocarcinoma AJCC v8 | Stage IV Intrahepatic Cholangiocarcinoma AJCC v8 | Advanced Cholangiocarcinoma

United States
University of Edinburgh

Not yet recruiting

Retinal Vessel Leakage in Cerebral Small Vessel Disease

Cerebral Small Vessel Diseases | Vascular Dementia | Lacunar Stroke
Oslo University Hospital

Not yet recruiting

Radiomics and Image Segmentation of Urinary Stones by Artificial Intelligence (RISUS_AI)

Renal Colic | Urolithiasis | Urinary Stone | Kidney Stone | Ureter Stone | Urosepsis | Obstruction Ureter
Northwestern University
National Cancer Institute (NCI); BrainUp Inc

Not yet recruiting

Triapine in Combination With Temozolomide for the Treatment of Patients With Recurrent Glioblastoma

Recurrent WHO Grade 2 Glioma | Recurrent Glioblastoma, IDH-Wildtype | Recurrent WHO Grade 3 Glioma | Recurrent WHO Grade 4 Glioma

United States
Masonic Cancer Center, University of Minnesota
National Cancer Institute (NCI)

Recruiting

Rectus Sheath Block With Liposomal Bupivacaine Versus Thoracic Epidural Analgesia for Pain Control Following Pancreatoduodenectomy

Pancreatic Neoplasm | Duodenal Neoplasm

United States
Mayo Clinic

Recruiting

Evaluation of 3D Surface Scanning for Virtual-CT Based Radiation Therapy Treatment Planning

Malignant Solid Neoplasm | Hematopoietic and Lymphatic System Neoplasm

United States
H. Lee Moffitt Cancer Center and Research Institute

Recruiting

Sequential Therapies Modeled on Evolutionary Dynamics for Breast Cancer

Metastatic Breast Cancer

United States
Ming Lv

Not yet recruiting

Metformin in Patients With Unruptured Vertebrobasilar Dissecting Aneurysms (METTLE) (METTLE)

Dissecting Aneurysm of Cerebral Artery
Yale University
National Institute of Neurological Disorders and Stroke (NINDS)

Not yet recruiting

Imaging Depression in Parkinson's Disease

Parkinson's Disease | Major Depressive Disorder
New York University
American Composers Orchestra

Recruiting

A Music and Visual Arts Digital Intervention in Teenagers to Promote Healthy Engagement With Social Media. (SMART)

Healthy Subjects | Mental Health Issue

United States
Children's Oncology Group

Not yet recruiting

A Study Using Risk Factors to Determine Treatment for Children With Favorable Histology Wilms Tumors (FHWT)

Stage I Kidney Wilms Tumor | Stage II Kidney Wilms Tumor | Stage III Kidney Wilms Tumor | Stage IV Kidney Wilms Tumor
OHSU Knight Cancer Institute
Oregon Health and Science University

Not yet recruiting

Onvansertib in Combination With Gemcitabine and Nab-paclitaxel for the Treatment of Patients With Locally-advanced, Unresectable, or Metastatic Pancreatic Ductal Adenocarcinoma

Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Metastatic Pancreatic Ductal Adenocarcinoma | Locally Advanced Pancreatic Ductal Adenocarcinoma | Unresectable Pancreatic Adenocarcinoma

United States
Osel, Inc.
National Cancer Institute (NCI); City of Hope Medical Center; Miyarisan Pharmaceuticals...

Recruiting

CBM588 Capsules in Combination With Nivolumab and Ipilimumab for the Treatment of Advanced Stage Kidney Cancer

Metastatic Renal Cell Carcinoma | Metastatic Clear Cell Renal Cell Carcinoma | Advanced Clear Cell Renal Cell Carcinoma | Stage III Renal Cell Cancer AJCC v8 | Stage IV Renal Cell Cancer AJCC v8 | Metastatic Sarcomatoid Renal Cell Carcinoma | Advanced Renal Cell Carcinoma | Advanced Sarcomatoid Renal...

United States
Assiut University

Not yet recruiting

Result Of Use Of Wide Awake Local Anaesthesia In Fixation Of Ankle Fractures

Local Anesthesia
National Cancer Institute (NCI)

Not yet recruiting

Testing the Addition of ASTX660 (Tolinapant) to the Usual Chemotherapy Treatment (Paclitaxel With or Without Bevacizumab) in Patients With Recurrent Ovarian Cancer

Recurrent Ovarian High Grade Serous Adenocarcinoma | Recurrent Platinum-Resistant Ovarian Carcinoma | Recurrent Fallopian Tube Clear Cell Adenocarcinoma | Recurrent Fallopian Tube Undifferentiated Carcinoma | Recurrent Ovarian Clear Cell Adenocarcinoma | Recurrent Ovarian Undifferentiated Carcinoma and other conditions
Narendranath Epperla
Eli Lilly and Company

Not yet recruiting

Pirtobrutinib With Rituximab for the Treatment of Newly Diagnosed Marginal Zone Lymphoma

Marginal Zone Lymphoma

United States
University of Virginia
National Center for Complementary and Integrative Health (NCCIH)

Recruiting

Optical Measurements of the Skin Surface to Infer Distinctions in Myofascial Tissue Stiffness (OptMeasSkin)

Tissue Pain

United States
Robert Bok, MD, PhD
National Cancer Institute (NCI)

Not yet recruiting

Magnetic Resonance (MR) Imaging With Hyperpolarized 13C-Pyruvate +/- 13C,15N-Urea in Patients With Prostate Cancer

Prostate Cancer

United States
Mayo Clinic

Not yet recruiting

Accuracy of 18F-rhPSMA-7.3 PET/ MRI for Prediction of Lymph Node Metastasis in Localized High-Risk Prostate Cancer

Localized Prostate Carcinoma | Stage I Prostate Cancer AJCC v8 | Stage II Prostate Cancer AJCC v8 | Stage III Prostate Cancer AJCC v8 | Stage IVA Prostate Cancer AJCC v8 | Oligometastatic Prostate Carcinoma

United States
Mayo Clinic

Recruiting

Reduced Dose Radiotherapy for the Treatment of Indolent Non-Hodgkin Lymphoma

Indolent B-Cell Non-Hodgkin Lymphoma | Recurrent Indolent Non-Hodgkin Lymphoma | Refractory Indolent Non-Hodgkin Lymphoma | Recurrent Indolent B-Cell Non-Hodgkin Lymphoma | Refractory Indolent B-Cell Non-Hodgkin Lymphoma

United States
University Hospital Tuebingen

Recruiting

Blood and Tissue Extraction for Immunological Examinations During Neoadjuvant Therapy of Soft Tissue Sarcomas

Soft Tissue Sarcoma Adult

Germany
Mayo Clinic
National Cancer Institute (NCI)

Not yet recruiting

Photoradiation With Verteporfin to Facilitate Immunologic Activity of Pembrolizumab in Unresectable, Locally Advance or Metastatic Pancreatic Cancer

Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Metastatic Pancreatic Adenocarcinoma | Locally Advanced Pancreatic Adenocarcinoma | Unresectable Pancreatic Adenocarcinoma

United States
Mayo Clinic

Not yet recruiting

Stereotactic Body Radiation Therapy Plus Androgen Receptor Pathway Inhibitor and Androgen Deprivation Therapy for Treatment of Metastatic, Recurrent Hormone-Sensitive Prostate Cancer, DIVINE Trial (DIVINE)

Recurrent Prostate Cancer | Castration-resistant Prostate Cancer | Stage IVB Prostate Cancer AJCC v8 | Recurrent Castration-Sensitive Prostate Carcinoma

United States
IRCCS Eugenio Medea

Recruiting

Myotonic Dystrophy Type 1 Congenital and Juvenile Form: From Diagnosis to Rehabilitation [MDCJ-NeuBeRe] (MDCJ-NeuBeRe)

Myotonic Dystrophy 1

Italy
Massachusetts General Hospital

Not yet recruiting

PET/MRI for Evaluation of Endometriosis

Endometriosis | Endometrioma

United States
Weill Medical College of Cornell University
Curium US LLC

Not yet recruiting

Feasibility of Intraoperative Tracing of Meningioma Using [Cu64]DOTATATE

Meningioma

United States
Endra Lifesciences

Not yet recruiting

Comparison of MRI-PDFF to TAEUS FLIP Device to Estimate Liver Fat Fraction in Adults

Steatosis of Liver

Germany
Katelyn Atkins

Not yet recruiting

Real-Time Atherosclerosis Activity After Thoracic Radiotherapy Using Sodium Fluoride Positron Emission Tomography

Oligometastatic Disease

United States

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