Evaluation of Low Flow and Normal Flow Anesthesia Management in Robotic Assisted Laparoscopic Surgeries

Robotic-assisted laparoscopic surgery has many advantages compared to conventional open surgery, such as less postoperative pain, shorter hospital stays, and faster recovery times. Robot-assisted surgeries require general anesthesia. In our clinic, we routinely apply low-flow anesthesia methods in addition to normal flow methods in many surgical applications, according to clinician preferences. The aim of this study is to determine the effects of low flow (0.5 lt/min) and normal flow (>1 lt/min) anesthesia applications in robotic-assisted laparoscopic surgeries.

To compare perioperative hemodynamic and respiratory parameters in terms of inhalation agent and soda lime consumption.

Study Overview

• Status: Not yet recruiting
• Conditions: Oncology
• Intervention / Treatment: Procedure: low-flow anesthesia

Detailed Description

Robotic surgery is the performance of laparoscopic surgery using a robotic interface. The robotic surgery system used today is called Da Vinci S. In surgeries performed with the help of a robot, the surgeon can work more precisely and with greater maneuverability. Therefore, an operation can be performed that is less traumatic for the patient than other methods.Robotic-assisted laparoscopic surgery has many advantages compared to conventional open surgery, such as less postoperative pain, shorter hospital stays, and faster recovery times. Robot-assisted surgeries require general anesthesia. In these applications, fresh gas flow in anesthesia systems can be made with traditional high, normal or low flow strategies, depending on the preference of the clinicians.Low-flow anesthesia creates a breathing air closer to physiological conditions during anesthesia by heating and humidifying the inhaled gases. In addition, it provides cost advantage by reducing inhalation agent consumption and reduces atmospheric pollution. It is suggested that the use of both fresh gas flow amounts does not pose a safety risk for patients, and that the use of low-flow anesthesia methods should be more widespread due to the advantages it provides. In our clinic, investigators routinely apply low-flow anesthesia methods in addition to normal flow methods in many surgical applications, according to clinician preferences. The aim of this study is to determine the effects of low flow (0.5 lt/min) and normal flow (>1 lt/min) anesthesia applications in robotic-assisted laparoscopic surgeries.

To compare perioperative hemodynamic and respiratory parameters in terms of inhalation agent and soda lime consumption.

• Study Type: Observational
• Enrollment (Estimated): 68

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult; Older Adult
• Accepts Healthy Volunteers: Yes

• Sampling Method: Non-Probability Sample

Study Population

Ages 18-75, ASA I,II, Patients undergoing robotic-assisted laparoscopic surgery

Description

Inclusion Criteria:

• Ages 18-75
• ASA I,II
• Patients undergoing robotic-assisted laparoscopic surgery

Exclusion Criteria:

• ASA III,IV,V
• Those with serious cardiac, respiratory, hepatic, renal disease
• People with mental status disorders, psychiatric illnesses
• Patients with hearing problems and glaucoma
• Desire to be out of work

Study Plan

How is the study designed?

Number of groups / cohorts

2

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
low-flow anesthesia; 0,5 lt/min	Procedure: low-flow anesthesia; 0,5 l/min >1 l/min; Other Names: normal flow anesthesia
normal flow anesthesia; >1 lt/min	Procedure: low-flow anesthesia; 0,5 l/min >1 l/min; Other Names: normal flow anesthesia

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Hemodynamic Parameters	It was aimed to compare heart rates in patients undergoing low flow (0.5 lt/min) and normal flow (>1 lt/min) anesthesia.	Perioperative period(approximately 3-6 hours)
Hemodynamic Parameters	It was aimed to compare blood pressure in patients undergoing low flow (0.5 lt/min) and normal flow (>1 lt/min) anesthesia.	Perioperative period(approximately 3-6 hours)
Respiratory parameters	It was aimed to compare oxygen saturation in patients undergoing low flow (0.5 lt/min) and normal flow (>1 lt/min) anesthesia.	Perioperative period(approximately 3-6 hours)
Respiratory parameters	It was aimed to compare endtidal carbon dioxide in patients undergoing low flow (0.5 lt/min) and normal flow (>1 lt/min) anesthesia.	Perioperative period(approximately 3-6 hours)
Inhalation agent (sevoflurane) consumption	It was aimed to compare inhalation agent (sevoflurane) consumption (lt) in patients undergoing low flow (0.5 lt/min) and normal flow (>1 lt/min) anesthesia.	Perioperative period(approximately 3-6 hours)
Soda lime consumption	It was aimed to compare soda lime consumption in patients undergoing low flow (0.5 lt/min) and normal flow (>1 lt/min) anesthesia. Soda lime consumption refers to the number of changes of the soda lime canister.	Perioperative period(approximately 3-6 hours)

Collaborators and Investigators

• Sponsor: Başakşehir Çam & Sakura City Hospital

Study record dates

Study Major Dates

• Study Start (Estimated): August 20, 2024
• Primary Completion (Estimated): January 20, 2025
• Study Completion (Estimated): January 20, 2025

Study Registration Dates

• First Submitted: May 14, 2024
• First Submitted That Met QC Criteria: May 21, 2024
• First Posted (Actual): May 28, 2024

Study Record Updates

• Last Update Posted (Actual): August 13, 2024
• Last Update Submitted That Met QC Criteria: August 11, 2024
• Last Verified: May 1, 2024

More Information

Terms related to this study

• Keywords: general anesthesia; low-flow anesthesia; robotic-assisted surgery
• Additional Relevant MeSH Terms: Neoplasms; Physiological Effects of Drugs; Central Nervous System Depressants; Anesthetics
• Other Study ID Numbers: 2024- 183

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No