Search clinical trials for: Lesch-Nyhan Disease

Total 382560 results

National Human Genome Research Institute (NHGRI)

Recruiting

A Natural History Study Seeks to Understand the Clinical, Genomic, Pharmacological, Laboratory, and Dietary Determinates of Pyrimidine and Purine Metabolism Disorders

Metabolic Disease | Purine-Pyrimidine Metabolism | AICDA, OMIM *605257, Immunodeficiency With Hyper-IgM, Type 2; HIGM2 | UNG, OMIM *191525, Hyper-IgM Syndrome 5 | NT5C3A<TAB>, OMIM *606224, Anemia, Hemolytic, Due to UMPH1 Deficiency | UMPS, OMIM *613891, Orotic Aciduria | DHODH, OMIM *126064,... and other conditions

United States
Uskudar University

Recruiting

Physiotherapy Assessment Based on the ICF Model in The Lesch-Nyhan Syndrome: Case Report

Lesch-Nyhan Syndrome

Turkey
Emalex Biosciences Inc.
Psyadon Pharma

Terminated

Ecopipam Treatment of Self-Injurious Behavior in Subjects With Lesch-Nyhan Disease

Lesch-Nyhan Disease | Self-injurious Behavior

Spain, United States
University of California, San Diego
BioMarin Pharmaceutical

Withdrawn

Trial of Kuvan in Lesch-Nyhan Disease

Behavioral Manifestations of Lesch-Nyhan Disease

United States
Psyadon Pharma

Completed

Safety and Tolerability of the D1 Dopamine Receptor Antagonist Ecopipam in Patients With Lesch-Nyhan Disease

Lesch-Nyhan Disease

United States
National Center for Research Resources (NCRR)
University of California, San Diego

Completed

Phase II Pilot Study of Aminoimidazole Carboxamide Riboside (AICAR), a Precursor of Purine Synthesis, for Lesch-Nyhan Disease

Lesch-Nyhan Syndrome
Assiut University

Not yet recruiting

Minerals Status in Relation to Overweight and Obese Adolescent

Mineral Deficiency

Egypt
Harbin Medical University
Shanghai Shenqi Medical Technology Co., Ltd

Not yet recruiting

RESTORE Imaging: an OCT-IVUS Imaging Substudy of RESTORE Trial

Acute Coronary Syndrome (ACS)

China
Hong Kong Metropolitan University

Not yet recruiting

Effects of Inspiratory Muscle Training on Respiratory and Diaphragmatic Functions, Balance Control, Exercise Capacity and Quality of Life in People After Stroke

Stroke
Alexion Pharmaceuticals, Inc.

Not yet recruiting

Study of Danicopan as Add-on Treatment to Ravulizumab or Eculizumab in Pediatric Participants With PNH Who Have Clinically Significant Extravascular Hemolysis

Paroxysmal Nocturnal Hemoglobinuria | PNH | Extravascular Hemolysis
University of North Carolina, Chapel Hill
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Not yet recruiting

Dose Optimization of Caffeine for HIE

Hypoxic-Ischemic Encephalopathy

United States
Peking University First Hospital

Recruiting

Fractional Flow Reserve-guided Stenting Versus Medical Therapy in Atherosclerosis Renal Artery Stenosis (FAIR)

Renal Artery Stenosis Atherosclerotic | Secondary Hypertension Renal Arterial

China
University of Florida

Not yet recruiting

Trial of Precision Medicine in Emergency Departments (TOPMEDs)

Pharmacogenomic Drug Interaction
Zhongda Hospital

Recruiting

Efficacy and Safety of 90Y Microsphere Combined With FOLFIRI and Bevacizumab in Second-line Treatment of CRLM

Colorectal Cancer Metastatic

China
Case Comprehensive Cancer Center
AbbVie; Genmab; Recordati Rare Diseases

Not yet recruiting

Study of Cytokine Release Syndrome Prophylaxis and Treatment With Siltuximab Prior to Epcoritamab

Non-Hodgkin Lymphoma | Cytokine Release Syndrome

United States
Changchun GeneScience Pharmaceutical Co., Ltd.

Not yet recruiting

Safety, Efficacy and Pharmacokinetic Behavior of Leuprolide Injectable Emulsion for Premenopausal Breast Cancer Subjects.

Breast Cancer Subjects

China
Zhujiang Hospital

Recruiting

A Prospective Cohort Study on the Correlation Between Patient Cotinine Levels and Intracranial Unruptured Aneurysm Wall Enhancement Based on High-resolution Magnetic Resonance Imaging

Cotinine Levels | Arterial Aneurysm Wall Enhancement on HRMRI

China
Sohag University

Recruiting

Clinical Spectrum and Outcome of Poisoning in Children Admitted to the Pediatric Emergency and Intensive Care Units at Sohag University Hospital

Acute Poisoning

Egypt
Fudan University

Not yet recruiting

Perioperative Surufatinib Plus Sintilimab Combined With Chemotherapy in Gastric/Gastroesophageal Junction Adenocarcinoma

Gastric Cancer | Gastro Esophageal Junction Cancer

China
Postgraduate Institute of Dental Sciences Rohtak

Recruiting

COMPARATIVE EVALUATION OF DIRECT PULP CAPPING AND COMPLETE PULPOTOMY IN MATURE PERMANENT MANDIBULAR MOLARS WITH CLINICAL SIGNS INDICATIVE OF MODERATE PULPITIS

Moderate Pulpitis

India
London North West Healthcare NHS Trust

Not yet recruiting

PSYLIVED: the Psychological Impacts of Living With an Inherited Colorectal Cancer Predisposition Syndrome (PSYLIVED)

Lynch Syndrome | Polyposis Syndrome, Hereditary Mixed, 1 | Polyposis Syndrome, Hereditary Mixed, 2

United Kingdom
Jonsson Comprehensive Cancer Center

Not yet recruiting

PH Weighted Chemical Exchange Saturation Transfer MRI-Based Surgical Resection to Improve Survival in Patients With Glioblastoma

Glioblastoma

United States
MAXVAX Biotechnology Limited Liability Company

Not yet recruiting

Efficacy, Safety and Immunogenicity Study of Recombinant Zoster Vaccine(CHO Cell) in Adults Aged 40 Years and Older

Herpes Zoster

China
Fudan University

Recruiting

Apatinib Combined With cdk4/6i in First-line Treatment for HR+/HER2- SNF4 Subtype Breast Cancer

Advanced Breast Cancer | HR+/HER2- Breast Cancer

China
Norwegian University of Science and Technology
Karolinska Institutet; Oslo University Hospital; Sahlgrenska University Hospital... and other collaborators

Recruiting

Exercise Training Study of Patients With Claudicatio Intermittens

Claudication, Intermittent

Norway, Sweden
Pfizer

Recruiting

A Study in Advanced/Metastatic Solid Tumors With the Study Medicine (PF-07329640) When Given Alone or In Combination (LTbR)

Melanoma | Colorectal Cancer | Non-Small Cell Lung Cancer | Urothelial Cancer | Advanced or Metastatic Solid Tumors

United States, Puerto Rico
University of Seville

Not yet recruiting

Relationship of Muscular Agenesis: Thin Plantar and Palmar Long as a Biomarker of Injury and Performance Marker in the Lower Limb and Upper Limb Respectively (MA-TP-PL)

Abnormality, Congenital

Spain
Bristol-Myers Squibb

Not yet recruiting

Patient and Physician Preference Study in Resectable, Non-small Cell Lung Cancer Treatments

Non-small Cell Lung Cancer (NSCLC)

United Kingdom
Nanfang Hospital, Southern Medical University

Recruiting

Research on the Mechanisms of Treatment Non-response in Inflammatory Bowel Disease Based on Multi-omics Technology

Inflammatory Bowel Diseases

China
BioMérieux

Recruiting

VIDAS® TBI Performance in Subjects With Mild Traumatic Brain Injury (mTBI)

Mild Traumatic Brain Injury

United States
Gulab Devi Hospital

Recruiting

Comparison Between Low Pressure Pneumoperitoneum With High Pressure Pneumoperitoneum in Post-operative Pain, Shoulder Tip Pain and Common Bile Duct Injuries in Patients Undergoing Laparoscopic Cholecystectomy

Pneumoperitoneum | Pain, Postoperative | Cholecystectomy

Pakistan
Bangladesh Institute of Research and Rehabilitation...
Pi Research and Development Center; Acme Laboratories Ltd.

Not yet recruiting

Real-World Evaluation of Omarigliptin for Type 2 Diabetes Meliitus in Bangladesh

Type2diabetes

Bangladesh
Cairo University

Not yet recruiting

Assessment of Green Dentistry Knowledge, Attitude and Implementation and Its Association With Sociodemographic Factors Among Dental Professionals in Cairo University.

Green Dentistry
Bilecik Seyh Edebali Universitesi

Not yet recruiting

The Effect of Mindfulness Training on Postoperative Pain - A Solomon Four Group Design

Postoperative Pain | Mindfulness Training | Inguinal Hernia Repair

Turkey
M.D. Anderson Cancer Center
Regeneron Pharmaceuticals

Not yet recruiting

A Phase 2 Study to Evaluate the Efficacy of the Combination of Cemiplimab and Cetuximab Prior to Salvage Surgery in Patients With Locally Recurrent (Stage 3-5) OCSCC

Locally Recurrent OCSCC

United States
Second Affiliated Hospital of Nanchang University

Recruiting

Analysis of Ocular Surface Microbiota in Dry Eye Patients After Refractive Surgery

Refractive Surgery

China
Laval University
Institut universitaire de cardiologie et de pneumologie de Québec, University... and other collaborators

Recruiting

Assessing Functional Capacity in Directly and Remotely Monitored Home-based Settings: A Protocol for a Multinational Validation Study in Individuals With Chronic Respiratory Diseases (6MST)

Interstitial Lung Disease | COPD Chronic Obstructive Pulmonary Disease

Canada, France
Johns Hopkins University

Not yet recruiting

Chocolate or Sevoflurane: Use of Parosmia to Facilitate More Cooperative Inhalation Inductions in Children

Anesthesia | Pediatrics
Shandong Provincial Hospital

Not yet recruiting

Henagliflozin's Impact on Prediabetes Remission

Glucose Metabolism Disorders | PreDiabetes | Prediabetic State | Type 2 Diabetes

China
Peking University Third Hospital

Recruiting

Observation on the Frailty Status of Lung Cancer Patients

Lung Cancer

China
University of Maryland, Baltimore

Not yet recruiting

Effect of RECK in Posterior Spinal Fusion

Degenerative Disc Disease | Degenerative Spondylolisthesis | Degenerative Lumbar Spinal Stenosis | Degenerative Disease

United States
Pfizer

Not yet recruiting

A Study to Learn About the Study Medicine PF-07934040 When Given Alone or With Other Anti-cancer Therapies in People With Advanced Solid Tumors That Have a Genetic Mutation.

Carcinoma, Non-Small-Cell Lung | Colorectal Neoplasms | Carcinoma, Pancreatic Ductal
Post Graduate Institute of Medical Education and...

Recruiting

A Trial to Compare Nebulized Amphotericin B and Nebulized Normal Saline as Maintenance in Increasing Time to Relapse in Patients With Chronic Pulmonary Aspergillosis Treated With 12 Months of Oral Itraconazole (NAB-CPA)

Chronic Pulmonary Aspergillosis | Aspergilloma | CPA

India
Fudan University

Not yet recruiting

The Efficacy and Safety of Cadonilimab (AK104) as Induction and Consolidation Therapy for Locally Advanced/Unresectable NSCLC Patients Receiving Concurrent Chemoradiotherapy

NSCLC | Locally Advanced Lung Carcinoma

China
University of Texas Southwestern Medical Center

Not yet recruiting

Respiratory Effects of Obesity in Children: Longitudinal Consequences After 6 Years of Aging

Childhood Obesity

United States
Guy's and St Thomas' NHS Foundation Trust
King's College Hospital NHS Trust; Imperial College Healthcare NHS Trust

Not yet recruiting

The PICM Risk Prediction Study - Application of AI to Pacing

Heart Failure | Pacemaker-Induced Cardiomyopathy | Pacemaker Complication

United Kingdom
Memorial Sloan Kettering Cancer Center
NeuroEndocrine Tumor Research Foundation (NETRF)

Recruiting

Defining Response Criteria for PET Scans for People With Neuroendocrine Tumors

Neuroendocrine Tumors

United States
Norwegian University of Science and Technology

Not yet recruiting

Multimodal Assesment of Alzheimer Patients (MultiAD)

Cognitive Impairment | Dementia | Mild Cognitive Impairment | Alzheimer Disease, Late Onset
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Humanized CD19-Specific CAR T Cells for the Treatment of Patients With Positive Relapsed or Refractory CD19 Positive B-Cell Acute Lymphoblastic Leukemia

Recurrent Acute Lymphoblastic Leukemia | Refractory Acute Lymphoblastic Leukemia

United States
M.D. Anderson Cancer Center
Kura Oncology, Inc.

Not yet recruiting

A Phase I Study Investigating the Combination of the Menin Inhibitor Ziftomenib With Venetoclax and Gemtuzumab in Pediatric Patients With Acute Myeloid Leukemia

Acute Myeloid Leukemia

United States

Search clinical trials for: Lesch-Nyhan Disease

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