Search clinical trials for: Life's Essential 8

Total 5789 results

Liverpool School of Tropical Medicine
University of Oxford

Recruiting

Using BCG Vaccine to Understand Tuberculosis Infection (Pilot BCG CHIM)

Tuberculosis

United Kingdom
All India Institute of Medical Sciences, New Delhi

Completed

Candida Associated Cytokines in Oral Leukoplakia

Oral Leukoplakia

India
Juno Therapeutics, Inc., a Bristol-Myers Squibb...
Celgene Corporation

Withdrawn

A Study to Compare the Efficacy and Safety of Lisocabtagene Maraleucel vs Investigator's Choice Options in Adult Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma, Whose Disease Has Failed Treatment With Both BTKi and BCL2i Therapies

Leukemia, Lymphocytic, Chronic, B-Cell

United States, Austria, Belgium, France, Germany, Italy, Netherlands, Norway, Spain, Sweden, United Kingdom
Shire

Completed

Pharmacokinetics (PK) of 20 mg Teduglutide in Participants With Moderately Impaired Hepatic Function Compared to Healthy Participants

Hepatic Impairment

United States
Neurocrine Biosciences

Completed

A Study of the Pharmacokinetics, Pharmacodynamics, and Safety of Opicapone in Subjects With Parkinson's Disease Taking Levodopa.

Parkinson Disease

United States
Eidos Therapeutics, a BridgeBio company
Celerion

Completed

Single and Multiple Ascending Dose Study Assessing the Safety, Tolerability, PK and PD of AG10

Amyloid Cardiomyopathy, Transthyretin-Related

United States
Nycomed
NPS Pharma

Completed

Pharmacokinetics of 10 mg Teduglutide in Subjects With Renal Impairment Compared to Healthy Subjects With Normal Renal Function

Renal Impairment

Germany
Green Cross Corporation
Atlantic Research Group

Completed

Phase 3 Study of Immune Globulin Intravenous (Human)IVIG-SN™ in Subjects With Primary Immunodeficiency

Immunologic Deficiency Syndrome

United States, Canada
Nycomed

Completed

Effects of Teduglutide on Cardiac Repolarisation and Conduction in Healthy Male and Female Volunteers

Healthy

Germany
Exciton Technologies Inc.
Alberta Heritage Foundation for Medical Research; Epidemiology Coordinating... and other collaborators

Unknown

Trial of exSALT SD7™ Compared to Xeroform® Petrolatum Dressing for the Management of Partial Thickness Donor Sites

Wound Infection | Wound Healing

Canada
University of Messina

Completed

Vascular and Skeletal Protective Effects of Genistein in Postmenopausal Women

Menopause | Osteopenia
The University of Tennessee, Knoxville

Completed

Evaluating Feasibility and Effectiveness of Computerized Mathematic Training

Math Teachers (Grades 2-8) | Math Students (Grades 2-8)

United States
UCB Pharma SA

Completed

A Multi-center, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Certolizumab Pegol in Combination With Methotrexate in the Treatment of Disease Modifying Antirheumatic Drugs (DMARD)-naïve Adults With Early Active Rheumatoid Arthritis (C-early)

Rheumatoid Arthritis

Germany, United States, Argentina, Australia, Austria, Belgium, Canada, Colombia, Czechia, France, Hungary, Ireland, Italy, Mexico, Monaco, Netherlands, Poland, Romania, Spain, Sweden, Switzerland, United Kingdom
UCB Pharma SA

Completed

Open-label, Randomized, Active-controlled Study of LEV Used as Monotherapy in Patients With Partial-Onset Seizures

Epilepsy | Partial Seizures

China
UCB Biopharma S.P.R.L.
PRA Health Sciences

Completed

Evaluating the Effectiveness of Neupro® (Rotigotine) and L-dopa Combination Therapy in Patients With Parkinson's Disease (NEUPART)

Idiopathic Parkinson's Disease

Germany, France, Italy, Spain, United Kingdom
UCB Pharma GmbH

Completed

Observation of Treatment With Certolizumab Pegol in Daily Practice (FasT)

Rheumatoid Arthritis

Germany
Sanol GmbH

Completed

A Double-blind, Double-dummy, Parallel, Active-controlled, Randomized Trial to Evaluate Efficacy & Safety in Anemia Subjects

Iron Deficiency Anemia

China
UCB Pharma

Completed

Caregivers' and Physicians' Treatment Preference in Parkinson Patients Treated With Neupro® Requiring Caregiver Support (CARE-ACT)

Idiopathic Parkinson's Disease

Germany
Astana Medical University
Medipol University

Unknown

Fluoroscopic Guided vs US-guided Percutaneous Nephrolithotripsy for the Treatment of Stone Disease

Kidney Diseases | Kidney Calculi | Urolithiasis | Ureteral Calculi | Kidney Stone
UCB Pharma

Completed

A Study of the Safety and Effectiveness of Lyophilized Certolizumab Pegol in the Treatment of Signs and Symptoms of Rheumatoid Arthritis and in Prevention of Joint Damage in Patients With Active Rheumatoid Arthritis

Rheumatoid Arthritis

United States, Argentina, Australia, Belgium, Bulgaria, Canada, Chile, Croatia, Czechia, Estonia, Finland, France, Hungary, Israel, Latvia, Lithuania, Mexico, New Zealand, Russian Federation, Serbia, Slovakia, Ukraine
UCB Pharma

Terminated

A 12 Week Study to Assess Changes in Joint Inflammation Using Ultrasonography in Patients With Rheumatoid Arthritis (RA) (SWIFT)

Rheumatoid Arthritis

United States
UCB Pharma SA
Parexel

Completed

Study to Assess the Short- and Long-term Efficacy of Certolizumab Pegol Plus Methotrexate Compared to Adalimumab Plus Methotrexate in Subjects With Moderate to Severe Rheumatoid Arthritis (RA) Inadequately Responding to Methotrexate

Rheumatoid Arthritis

Romania, United States, Australia, Austria, Bulgaria, Canada, Czechia, France, Germany, Greece, Hungary, Ireland, Italy, Mexico, Monaco, Poland, Portugal, Spain, Switzerland, United Kingdom
UCB BIOSCIENCES, Inc.

Completed

Trial to Demonstrate the Efficacy and Safety of Conversion to Lacosamide Monotherapy for Partial-onset Seizures (ALEX-MT)

Epilepsy

Austria, United States, Australia, Canada, Denmark, France, Germany, Ireland, Italy, Poland, Puerto Rico, Spain, United Kingdom
UCB Pharma

Completed

Effect on RLS Symptom Severity After Switching to Neupro® in Patients Who Previously Experienced Augmentation (AURORA)

Restless Legs Syndrome

Germany
UCB Pharma

Terminated

Certolizumab Pegol for the Treatment of Patients With Active Rheumatoid Arthritis (RA) and Crohn's Disease (CD)

Rheumatoid Arthritis | Crohn's Disease

Russian Federation
UCB Japan Co. Ltd.

Completed

An Open Label Study of Levetiracetam in Japanese Pediatric Patients With Partial Seizures

Epilepsy | Partial Seizures

Japan
Cukurova University

Completed

Ketamine and Magnesium in Erector Spinae Plane Block

Postoperative Analgesia

Turkey
ANRS, Emerging Infectious Diseases
Mylan Laboratories

Active, not recruiting

ANRS 12372 MODERATO Study (MODERATO)

HIV-1-infection

Côte D'Ivoire, Burkina Faso, Cameroon
Boehringer Ingelheim

Completed

A Study in Healthy Men to Test How Itraconazole Influences the Amount of BI 894416 in the Blood

Healthy

Germany
The University of Texas Medical Branch, Galveston
National Institute of General Medical Sciences (NIGMS)

Completed

Assessment of Mechanisms of Improved Wound Healing

Burns

United States
Unity Health Toronto
University of Toronto; Toronto Public Health; Ontario College of Art and Design...

Withdrawn

Surviving Opioid Overdose With Naloxone Education and Resuscitation Trial (SOONER) (SOONER)

Opioid-Related Disorders | Opioid Use | Education | Opioid Withdrawal | Opioid Overdose | Resusitation

Canada
Pocket Naloxone Corp

Completed

Pharmacokinetic Evaluation of a New Naloxone Nasal Swab, Naloxone Nasal Spray, and Intramuscular Naloxone Injection in Healthy Volunteers

Opioid Overdose

Canada
Medical University of Vienna
Medical University of Graz; Medical University Innsbruck; SMZ-Ost Donauspital; Hospital... and other collaborators

Unknown

Austrian CoronaVirus Adaptive Clinical Trial (COVID-19) (ACOVACT)

COVID-19

Austria
Cairo University

Unknown

Intraperitoneal Dexamethasone vs Dexamethasone Plus Magnesium Sulphate for Pain Relief in Laparoscopic Cholecystectomy

Pain, Postoperative

Egypt
ASLAN Pharmaceuticals

Completed

Study of ASLAN001 in Combination With Capecitabine in MBC That Has Failed on Prior Trastuzumab

Metastatic Breast Cancer

Australia, Hong Kong, Korea, Republic of, New Zealand, Philippines, Singapore, Taiwan
National Institute on Drug Abuse (NIDA)
Cincinnati MDRU

Completed

Buprenorphine/Naloxone for Opiate-Dependence Treatment - 1

Substance-Related Disorders | Opioid-Related Disorders

United States
National Institute on Drug Abuse (NIDA)
New York MDRU

Completed

Buprenorphine and Naloxone Combination Study - 10

Opioid-Related Disorders | Heroin Dependence

United States
Assiut University

Not yet recruiting

Magnesium Sulfate as an Adjuvant to Propofol During Consious Sedation in Colonoscopy

Magnesium | Intraoperative Analgesia
Assiut University

Not yet recruiting

Block Pressor Response to Intubation

Intubation Complication
Guangdong Provincial People's Hospital

Not yet recruiting

Neoadjuvant Treatment With Palbociclib and Exemestane Plus Trastuzumab and Pyrotinib in Estrogen Receptor (ER)-Positive, HER2-positive Breast Cancer

Neoadjuvant Treatment for HER2-positive, ER-positive Breast Cancer
Massachusetts General Hospital

Not yet recruiting

Buprenorphine/Naloxone Micro-Dosing for Postoperative Pain Management in Opioid-Tolerant Patients

Post-operative Pain

United States
University of Sao Paulo General Hospital

Recruiting

Dose of Magnesium Sulfate Infusion in Obese

Analgesia | Obese

Brazil
Vastra Gotaland Region

Recruiting

Research Study for Treatment of Children and Adolescents With Acute Myeloid Leukaemia 0-18 Years (AML2012)

Pediatric Acute Myeloblastic Leukemia

Belgium, Denmark, Estonia, Finland, Hong Kong, Iceland, Netherlands, Norway, Sweden
University of Monastir

Completed

Treatment of Renal Colic in the Emergency Department: Comparison Between Magnesium Sulfate and Lidocaine.

Renal Colic

Tunisia
Arcus Biosciences, Inc.

Completed

A Drug-Drug Interaction Study to Evaluate the Effect of Itraconazole on the Pharmacokinetic Profile of Etrumadenant in Healthy Adult Participants

Healthy Participants

United States
Jiangsu HengRui Medicine Co., Ltd.

Completed

A Study to Evaluate the Effect of Itraconazole on Pharmacokinetics (PK) of SHR8554 in Healthy Adult Subjects

Healthy

China
Fayoum University Hospital

Completed

The Analgesic Efficacy of Magnesium and Ketorolac in Ultrasound Supraclavicular Block

Postoperative Pain

Egypt
NSABP Foundation Inc
Royal Marsden NHS Foundation Trust; Pfizer; Institute of Cancer Research, United...

Completed

A Phase II Randomized Study Evaluating the Biological and Clinical Effects of the Combination of Palbociclib With Letrozole as Neoadjuvant Therapy in Post-Menopausal Women With Estrogen-Receptor Positive Primary Breast Cancer (PALLET)

Breast Cancer | Breast Tumors | Breast Carcinoma

United Kingdom, United States, Canada
University of Sao Paulo General Hospital

Completed

Magnesium Sulfate Dose in Obese Patients.

Obesity | Postoperative Pain | Magnesium Sulfate

Brazil
INSYS Therapeutics Inc

Completed

A Study to Compare Bioavailability of Naloxone Nasal Spray and Naloxone Hydrochloride (HCl) Intramuscular Injection (IM) in Healthy Volunteers

Healthy Volunteer

United States

Search clinical trials for: Life's Essential 8

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