Search clinical trials for: Severe Depressive Episode

Total 56940 results

Max-Planck-Institute of Psychiatry

Recruiting

Deep Phenotyping for Clinical Inferring Response in Treatment Resistant Depression (DECIDE)

Depressive; Disorder, Major, Single Episode, Major, With Psychotic Symptoms | Depressive; Disorder, Major, Single Episode, Major (Without Psychotic Symptoms) | Depressive Disorder, Major, Recurrent, With Psychotic Symptoms | Depressive Disorder, Major, Recurrent, Without Psychotic Symptoms and other conditions

Germany
University of Bern
Swiss National Science Foundation; University of Zimbabwe

Not yet recruiting

The Friendship Bench Plus Trial (FB+)

Major Depressive Disorder | Severe Depressive Episode Without Psychotic Symptoms

Zimbabwe
Sheba Medical Center

Recruiting

Development of a Model for Digital Monitoring of the Mental State of the Hospitalized Patient

Personality Disorders | Depressive Disorder | Mood Disorders | Schizophrenia | Schizoaffective Disorder | Anxiety Disorders | Bipolar Disorder | Severe Mental Disorder | Psychotic Episode

Israel
Mental Health Services in the Capital Region, Denmark
Innovation Fund Denmark

Recruiting

T-PEMF Headband Stimulation for Patients With Moderate to Servere Depression

Moderate Depression | Recurrent Depressive Disorder, Current Episode Moderate | Severe Depressive Episode Without Psychotic Symptoms | Recurrent Depressive Disorder, Current Episode Severe Without Psychotic Symptoms

Denmark
The George Institute
National Health and Medical Research Council, Australia; Medical University... and other collaborators

Recruiting

The RAFT ECT Study (RAFT-ECT)

Major Depressive Episode

United States, Australia
Centre Hospitalier Universitaire de Nīmes

Recruiting

Add-on Buprenorphine at Analgesic Doses for the Treatment of Severe Suicidal Ideas During a Major Depressive Episode (BUPRIS)

Suicidal Ideation | Major Depressive Episode

France
Tonix Pharmaceuticals, Inc.
Rho, Inc.

Completed

Study to Evaluate TNX-601 ER Monotherapy Versus Placebo in Patients With Major Depressive Disorder (MDD) (UPLIFT)

Depressive Disorder | Depression | Depressive Symptoms | Depressive Disorder, Major | Depressive Episode | Depression Severe

United States
Sonder Behavioral Health and Wellness

Completed

Practical Application of Accelerated iTBS for MDD

Major Depressive Disorder | Major Depressive Disorder, Recurrent Episode, Severe | Major Depressive Disorder, Recurrent, Moderate

United States
Max-Planck-Institute of Psychiatry

Completed

Feasibility of a Novel Process-based Treatment for Patients With Psychosis (PROBAS)

Schizophrenia | Schizoaffective Disorder | Delusional Disorder | Schizotypal Disorder | Brief Psychotic Disorder | Shared Psychotic Disorder | Other Psychotic Disorder Not Due to A Substance or Known Physiological Condition | Unspecified Psychosis Not Due to a Substance or Known Physiological Condition and other conditions

Germany
Stanford University

Terminated

MRS and Medication Response: A Pilot Study

Major Depressive Disorder | Major Depressive Episode | Major Depressive Disorder, Recurrent | Major Depression Mild | Major Depression Moderate | Major Depression Severe

United States
Merck Sharp & Dohme LLC

Terminated

Safety and Efficacy of MK-6096 as Adjunctive Therapy in Participants With Major Depressive Disorder And Partial Response to Antidepressant Monotherapy (MK-6096-022)

Major Depressive Disorder, Recurrent
GlaxoSmithKline

Completed

Safety and Efficacy Study in Patients With Major Depressive Disorder

Depressive Disorder

Russian Federation
University of North Carolina, Chapel Hill
Foundation of Hope, North Carolina

Completed

Study of Lurasidone in Treating Antipsychotic Naive or Quasi-Naive Children and Adolescents

Schizophrenia | Schizoaffective Disorder | Schizophreniform Disorder | Autistic Disorder | Child Development Disorders, Pervasive | Psychosis NOS | Bipolar I Disorder | Asperger Syndrome | Bipolar II Disorder | Severe Major Depression With Psychotic Features | Mood Disorder NOS | Single Episode Major Depression... and other conditions

United States
Eli Lilly and Company
Boehringer Ingelheim

Completed

A Study Comparing Duloxetine to Other Antidepressants in the Treatment of Severe Depression (TRY FIRST)

Depression

United States
Shanghai Mental Health Center

Not yet recruiting

Effectiveness of MST Versus ECT for Major Depressive Episode

Major Depressive Disorder (MDD)

China
Taizhou Mabtech Pharmaceutical Co.,Ltd

Not yet recruiting

Comparative Study of CMAB015 and Secukinumab for Patients With Moderate to Severe Plaque Psoriasis

Psoriasis
Rigshospitalet, Denmark

Not yet recruiting

Microdialysis and Jugular Bulb Glucose Profiles During Hyperglycaemic Clamping in Patients With Severe Acute Brain Injury (CLAMP)

Acute Brain Injury

Denmark
Indivior Inc.

Not yet recruiting

Proof of Concept and Dose-ranging Study of INDV-2000 in Individuals With Moderate to Severe Opioid Use Disorder

Opioid Use Disorder
Kintsugi Mindful Wellness, Inc.
Sonar Strategies; Vituity Psychiatry

Recruiting

Kintsugi Voice Device Pilot Study

Depression | Depression Moderate | Depression Severe | Depression Mild

United States
Teoxane SA

Recruiting

TEOSYAL® PureSense ULTRA DEEP Versus Restylane® Lidocaine for the Correction of Moderate to Severe Nasolabial Folds in Chinese Adults

Nasolabial Folds

China
University of Health Sciences Lahore

Not yet recruiting

Cisternostomy Vs Decompressive Craniectomy for Severe Traumatic Brain Injury

Severe Traumatic Brain Injury
Capital Medical University
The Second People's Hospital of Dali Bai Autonomous Prefecture; Wuhu Fourth... and other collaborators

Not yet recruiting

Esketamine Treatment for Depressive Episodes With Suicidal Ideation in Mood Disorders

Mood Disorders | Suicidal Ideation | Depressive Episode
The Fourth Affiliated Hospital of Zhejiang University...

Not yet recruiting

Efficacy and Safety of Oliceridine for Moderate to Severe Acute Pain After Orthopedic Surgery

Postoperative Pain
The Second Affiliated Hospital of Chongqing Medical...
Wuhan University; Tongji Hospital; The First Affiliated Hospital of Zhengzhou... and other collaborators

Recruiting

Effect of Noise Isolation on the Incidence of Moderate to Severe Postoperative Pain

Postoperative Pain

China
Unity Health Toronto

Recruiting

Susceptibility for Entrainment: Role of Ventilator Settings on the Occurrence of Reverse Triggering and Its Physiological Consequences - the SEVeRe Study (SEVERE)

Respiration, Artificial | Reverse Triggering

Canada
Massachusetts General Hospital

Not yet recruiting

CPAP in Patients With Severe Obesity After Anesthesia

Anesthesia Morbidity | Obesity, Abdominal | Ventilator Lung | Apnea, Obstructive Sleep | Atelectases, Postoperative Pulmonary
Gerbera Therapeutics, Inc.

Not yet recruiting

A Study to Assess the Efficacy, Safety, and Tolerability of Oral NORA520 in Adults With Severe Postpartum Depression (NuMom)

Postpartum Depression | Depression, Postpartum | Postnatal Depression | Post-partum Depression | Post-Natal Depression

United States
University Hospital, Rouen

Not yet recruiting

Nebulized Fentanyl in Healthy Volunteers (AEROfen)

Emergencies | Analgesia

France
Eli Lilly and Company

Not yet recruiting

A Study of Lebrikizumab (LY3650150) With/Without Topical Corticosteroid Treatment in Participants With Moderate-to-Severe Atopic Dermatitis

Atopic Dermatitis

China, Korea, Republic of
Baylor College of Medicine
University of Texas

Recruiting

Telehealth Behavioral Activation for Teens

Depression | Depression Moderate | Depression Severe | Suicide and Self-harm | Depression in Adolescence | Depression Mild

United States
Kodiak Sciences Inc

Recruiting

A Study to Evaluate the Efficacy and Safety of Tarcocimab Tedromer Compared With Sham Treatment in Participants With Moderately Severe to Severe Non-proliferative Diabetic Retinopathy (NPDR) (GLOW2)

Non-proliferative Diabetic Retinopathy

United States, Puerto Rico
Janssen Research & Development, LLC

Recruiting

A Study of Guselkumab in Pediatric Participants With Moderately to Severely Active Ulcerative Colitis (QUASAR Jr)

Colitis, Ulcerative

Belgium, United States, China, Denmark, Japan, Italy, Turkey, Poland
Tasly Pharmaceutical Group Co., Ltd

Recruiting

A Study of the Effectiveness and Safety of JS1-1-01 in Patients With Moderate to Severe Depression

Depression

China
Shanghai 6th People's Hospital

Not yet recruiting

Safety and Efficacy of Enhanced Recovery After Surgery in Neurocritical Care

Traumatic Brain Injury | Cerebrovascular Disease | Neurocritical Care | Moderate or Severe Coma

China
EMS

Not yet recruiting

Efficacy and Safety of DIT112 in the Treatment of Moderate to Severe Pain After Dental Surgery for the Extraction of Impacted Third Molars (ALIV)

Moderate Pain | Severe Pain
Centre Integre Universitaire de Sante et Services...

Recruiting

The Effects of Lemborexant on the Ability to Sleep During Daytime

Shift-Work Sleep Disorder

Canada
Al-Azhar University

Not yet recruiting

Combined Procedures in the Treatment of Severe Acne Scars

Atrophic Acne Scar
Mclean Hospital
Baszucki Family Foundation

Recruiting

Ketogenic and Nutritional Interventions for First Episode Bipolar Disorder

Schizoaffective Disorder | Psychosis | Bipolar I Disorder

United States
RenJi Hospital

Not yet recruiting

The Effects of Remimazolam on the Incidence of Severe Hypoxia During Sedated Hysteroscopy for Assisted Reproduction in Overweight or Obese Patients (RP)

Hypoxia | Overweight or Obesity | Hysteroscopy

China
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Intranasal Sufentanil for Analgesia of Severe Sickle Cell Vaso-occlusive Pain Crisis in the Pediatric (INVOPE)

Vaso-occlusive Crisis
University Hospital, Limoges

Not yet recruiting

Trial Evaluating the Rate of Pneumothorax in Severe Emphysema Secondary to Endoscopic Volume Reduction With Two-stage ZEPHYR® Valves Versus Endoscopic Volume Reduction With One-stage ZEPHYR® Valves (REPEAT)

COPD

France
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
First Affiliated Hospital, Sun Yat-Sen University; First Affiliated Hospital... and other collaborators

Recruiting

TEER for Severe DMR of Low to Intermediate Surgery Risk

Mitral Regurgitation

China
University Hospital, Strasbourg, France

Recruiting

Non-opioid Anesthesia in Bariatric Surgery (BARIA)

Severe Obesity

France
Brugmann University Hospital

Not yet recruiting

Psilocybin-Assisted Therapy for Severe Alcohol Use Disorder

Severe Alcohol Use Disorder
Centre Hospitalier Universitaire, Amiens
CH Montdidier

Recruiting

Intestinal Microbiota Profiling in Severe Acute Alcoholic Hepatitis Patients (HepatAlc-IM)

Corticosteroids | Intestinal Microbiota | Alcohol | Severe Acute Alcoholic Hepatitis

France
University of Manitoba

Recruiting

Post Spinal Hemodynamic Changes in Aortic Stenosis and Mitral Regurgitation by VIS Index and Echocardiography

Severe Aortic Valve Stenosis | Severe Mitral Valve Regurgitation

Canada
The Royal Ottawa Mental Health Centre

Not yet recruiting

Comparing the Efficacy of fMRI-Guided vs. Standard iTBS in Treating Depression

Depression | Depressive Disorder, Major | Depressive Episode

Canada
Apex Labs Ltd.

Not yet recruiting

Evaluation of Psilocybin-Assisted Psychotherapy in Treating Severe Depression in Patients With PTSD (SUMMIT-90)

Depression | Post-traumatic Stress Disorder
Ruijin Hospital

Recruiting

Organ Protective Effect of Cetirizine In Patients With Severe Burns

Burns

China
University of Massachusetts, Worcester
Yale University; Worcester Polytechnic Institute; Michigan State University

Not yet recruiting

A Text Messaging Intervention to Reduce Perinatal Depression Risk (Perinatal TMI)

Major Depressive Episode

United States

Search clinical trials for: Severe Depressive Episode

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