Search clinical trials for: Sheffield

Total 1984 results

Tris Pharma, Inc.

Not yet recruiting

A Study of Cebranopadol for the Treatment of Acute Pain After Bunionectomy (ALLEVIATE2)

Acute Pain

United States
Orthofix s.r.l.

Not yet recruiting

Retrospective Study on Clinical Performance and Safety Profile of MJ-Flex Elastic Nail (MJ-Flex)

Fractures, Bone

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust

Not yet recruiting

Transcutaneous Vagus Nerve Stimulation for Language Recovery After Stroke (TRANSLATES)

Aphasia | Chronic Stroke

United Kingdom
Sheffield Hallam University
King's College London; University of Nottingham; University of Illinois at Chicago and other collaborators

Recruiting

Cardiopulmonary Exercise Tests in Patients With Long COVID (PREPP-19)

Long COVID | COVID Long-Haul

United States, India, United Kingdom
Royal United Hospitals Bath NHS Foundation Trust
Sheffield Teaching Hospitals NHS Foundation Trust; Royal Free Hospital NHS... and other collaborators

Not yet recruiting

Developing the Probability Algorithm for Pulmonary Hypertension Echocardiography (DRAPE)

Pulmonary Hypertension

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust

Not yet recruiting

Investigating the Tolerability and Feasibility of Transcutaneous Vagus Nerve Stimulation Following Aneurysmal Subarachnoid Haemorrhage (tVNS in aSAH)

Subarachnoid Haemorrhage From Cerebral Aneurism Rupture

United Kingdom
University of Bergamo
University of Palermo; University of Sheffield; University of Ottawa; Leiden University and other collaborators

Not yet recruiting

Routine Outcome Monitoring and Feedback Informed Therapy in Italy (FIT-ITALY)

Feedback, Psychological

Italy
AstraZeneca

Recruiting

Efficacy, Safety and Tolerability of Balcinrenone/Dapagliflozin Compared to Dapagliflozin in Adults With Chronic Kidney Disease. (MIRO-CKD)

Chronic Kidney Disease

Spain, Italy, China, Vietnam, United States, Brazil, Canada, Malaysia, Poland, Taiwan, Austria, Bulgaria, Chile, United Kingdom, Japan
University of Sheffield
Nottingham University Hospitals NHS Trust

Not yet recruiting

Time and Cost-implications of Intraoral Scans vs Alginate Impressions: A Randomised Controlled Trial

Chairside Time and Costs Associated With Intraoral Scanning Versus Alginate Impressions

United Kingdom
Acumen Pharmaceuticals

Recruiting

A Study to Evaluate Efficacy and Safety of Intravenous ACU193 in Participants With Early Alzheimer's Disease (ALTITUDE-AD) (ALTITUDE-AD)

Alzheimer Disease

United States, France, Italy, Germany, Spain, Canada, Poland, United Kingdom
Milton S. Hershey Medical Center
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); University... and other collaborators

Not yet recruiting

Closed Loop and Education for Hypoglycemia Awareness Restoration (CLEAR)

Diabetes Mellitus, Type 1

United States, Australia, United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield; Sheffield Hallam University

Not yet recruiting

Exercise to Boost Immunity in Advanced Cancer (BICEP)

Pancreatic Cancer | Mesothelioma; Lung

United Kingdom
AstraZeneca

Recruiting

Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function (BalanceD-HF)

Heart Failure and Impaired Kidney Function

Spain, France, Germany, Italy, United States, Argentina, Czechia, Vietnam, Peru, China, Philippines, Austria, Canada, Japan, Malaysia, Poland, Taiwan, Thailand, Brazil, Finland, Greece, Israel, Mexico, United Kingdom, Turkey, Colombia, Slov... and more
Eli Lilly and Company

Not yet recruiting

A First-In-Human Study of LY3954068 in Participants With Early Symptomatic Alzheimer's Disease

Alzheimer Disease

United States, United Kingdom, Japan
University of Sheffield
Sheffield Children's NHS Foundation Trust

Recruiting

Accommodation Response in Hypermetropic Anisometropia (ARIHA Study) (ARIHA)

Accommodation Disorder | Anisometropic Amblyopia

United Kingdom
AstraZeneca

Recruiting

A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease (THARROS)

COPD (Chronic Obstructive Pulmonary Disease)

France, Denmark, Italy, Spain, United States, Canada, Argentina, Japan, Colombia, Germany, Peru, Brazil, China, India, Thailand, Austria, Serbia, Malaysia, Philippines, Poland, Taiwan, Greece, Norway, Sweden, Mexico, Romania, Korea, Republic... and more
Encoded Therapeutics

Recruiting

A Clinical Study to Evaluate the Safety and Efficacy of ETX101, an AAV9-Delivered Gene Therapy in Children With SCN1A-positive Dravet Syndrome (UK Only)

Dravet Syndrome

United Kingdom
University of Sheffield

Not yet recruiting

Using Video Interaction Guidance (VIG) With Children Who Have Language Delays.

Language Development Disorders
Mylan Specialty, LP

Recruiting

Study of MR-107A-02 for the Treatment of Acute Postoperative Pain Following Bunionectomy

Pain | Acute Pain | Post Operative Pain

United States
Mylan Specialty, LP

Recruiting

Study of MR-107A-02 for the Treatment of Acute Postoperative Pain Following Herniorrhaphy

Pain | Acute Pain | Post Operative Pain

United States
Hemab ApS

Recruiting

A Phase 1/2 Study to Investigate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of HMB-001 in Glanzmann Thrombasthenia

Glanzmann Thrombasthenia

United States, Belgium, France, Italy, Netherlands, United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield; Nottingham Trent University; Sheffield Hospitals Charity

Recruiting

Biomarkers of aHSCT (BIO-MS)

Multiple Sclerosis, Relapsing-Remitting

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust

Not yet recruiting

The Psychological Impact of GTN on Women Who Have Completed Chemotherapy Treatment (PI-GTN)

Gestational Trophoblastic Neoplasia

United Kingdom
AstraZeneca
Parexel

Recruiting

A Study to Describe the Characteristics, Health Care Interventions and Outcomes of Patients With Major Bleedings in the Presence of Factor Xa Inhibitor Treatment (REVERXaL)

Major Bleeding

United States, Japan, Germany, United Kingdom
Royal United Hospitals Bath NHS Foundation Trust
Janssen Research & Development, LLC; Sheffield Teaching Hospitals NHS Foundation... and other collaborators

Recruiting

ADOPT: Improving Diagnosis of Pulmonary Hypertension With AI and Echo (ADOPT)

Pulmonary Hypertension

United Kingdom
University of Oxford

Recruiting

A Study to Compare Two Dosing Regimens for a New Malaria Vaccine

Infections | Vector Borne Diseases | Protozoan Infections | Malaria | Malaria,Falciparum | Parasitic Disease

United Kingdom
Novo Nordisk A/S
Duke Clinical Research Institute

Not yet recruiting

ARTEMIS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With a Heart Attack (ARTEMIS)

Cardiovascular Risk | Acute Myocardial Infarction (AMI)

Canada, China, United States, Germany, Spain, Korea, Republic of, Netherlands, Australia, Italy, Denmark, India, United Kingdom, Argentina, Turkey, Mexico, Malaysia, Czechia, Poland, Brazil, France, Japan, Bulgaria, Greece, Israel
Eli Lilly and Company
Loxo Oncology, Inc.

Recruiting

A Study of LY3537982 Plus Immunotherapy With or Without Chemotherapy in Participants With Non-Small Cell Lung Cancer (NSCLC) With a Change in a Gene Called KRAS G12C (SUNRAY-01)

Carcinoma, Non-Small-Cell Lung | Neoplasm Metastasis

United States, Taiwan, Belgium, Australia, Japan, United Kingdom, Spain, China, France, Germany, Austria, Korea, Republic of, Hungary, Switzerland, Turkey, Mexico, Norway, Italy, Portugal, Netherlands, India, Romania, Canada, Denmark, G... and more
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield; Crohn's & Colitis UK; Sheffield Centre for Health and...

Recruiting

Early Bowel Resection for Terminal Ileal Crohn's Disease (E-BRIC)

Crohn Disease

United Kingdom
The University of Texas Medical Branch, Galveston

Recruiting

Correlates of CRCI and Gut Microbiome Dysbiosis; a Pilot Study

Cancer

United States
Sheffield Children's NHS Foundation Trust
Sheffield Hallam University

Recruiting

Central Apnoea Monitor Study

Sleep Apnea

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield; National Institute for Health Research, United Kingdom

Recruiting

SDF for the Management of Dental Caries in Children in Primary Dental Care: Protocol for a Feasibility Study

Dental Caries in Children

United Kingdom
Sheffield Hallam University
Chesterfield Royal Hospital NHS Foundation Trust

Not yet recruiting

What Are Persistent Lower Back Pain Patients' Views of Sleep Health Within an Outpatient Musculoskeletal Physiotherapy Setting?

Lower Back Pain | Chronic Low-back Pain | Sleep Disturbance | Persistent Lower Back Pain
University of Oxford
University of Sheffield; McPin Foundation

Recruiting

Ketogenic Diet for Treatment-Resistant Depression: Dietary Interventions for MEntal Health Study (DIME) (DIME)

Depressive Disorder | Depression | Treatment Resistant Depression | Mental Illness | Mental Disorder

United Kingdom
Amgen

Recruiting

A Study of Apremilast in Pediatric Participants in Children With Mild to Moderate Plaque Psoriasis

Plaque Psoriasis

United States
The University of Texas Health Science Center,...
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Recruiting

Modernizing Perinatal Syphilis Testing

Syphilis

United States
Alexion Pharmaceuticals, Inc.

Recruiting

Phase 3 Study of ALXN1850 in Pediatric Participants With HPP Previously Treated With Asfotase Alfa (CHESTNUT)

Hypophosphatasia

Australia, United States, Japan, Germany, Turkey, Italy, India, France, United Kingdom, Argentina, Canada
Alexion Pharmaceuticals, Inc.

Recruiting

Phase 3 Study of ALXN1850 Versus Placebo in Adolescent and Adult Participants With HPP Who Have Not Previously Been Treated With Asfotase Alfa (HICKORY)

Hypophosphatasia

Italy, Spain, Israel, Korea, Republic of, Belgium, Germany, United States, China, France, Taiwan, Austria, Japan, India, Australia, Argentina, Poland, Turkey, Brazil, Canada, Thailand, United Kingdom, Slovakia, Czechia
AstraZeneca

Recruiting

A Study to Investigate the Effect on Lung Function of an Approved COPD Treatment (BGF, With HFA Propellant) Compared to BGF Formulated With a New Propellant (HFO) in Participants 40 to 80 Years of Age With COPD

COPD (Chronic Obstructive Pulmonary Disease)

United States, Korea, Republic of, Argentina, Turkey, Vietnam, Malaysia, Philippines, Thailand, Hungary, Mexico, Canada, India, Bulgaria, Poland
AstraZeneca

Recruiting

Efficacy and Safety of Tozorakimab in Symptomatic Chronic Obstructive Pulmonary Disease With a History of Exacerbations (MIRANDA)

Chronic Obstructive Pulmonary Disease (COPD)

China, United States, Denmark, Italy, Germany, Hungary, Netherlands, Spain, United Kingdom, Belgium, Argentina, Bulgaria, Canada, India, Japan, Vietnam, Brazil, Malaysia, Thailand, France, Mexico, Greece, Poland, Korea, Republic of, Peru, Chil... and more
Royal United Hospitals Bath NHS Foundation Trust
Sheffield Teaching Hospitals NHS Foundation Trust; Royal Free Hospital NHS... and other collaborators

Recruiting

Improving Pulmonary Hypertension Screening by Echocardiography (IMPULSE)

Pulmonary Hypertension

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust

Recruiting

Use of PET-MR in Head and Neck Cancer Patients - Diagnostic and Therapeutic Applications

Head and Neck Cancer

United Kingdom
Sheffield Children's NHS Foundation Trust

Recruiting

Robot-controlled Magnet-Assisted Capsule Endoscopy (MACE)

Abdominal Pain | Upper Gastrointestinal Symptoms

United Kingdom
Merck Sharp & Dohme LLC

Recruiting

MK-0616 (Oral PCSK9 Inhibitor) Cardiovascular Outcomes Study (MK-0616-015) CORALreef Outcomes

Arteriosclerosis | Hypercholesterolaemia

United States, Taiwan, Canada, Israel, New Zealand, Hong Kong, Argentina, Korea, Republic of, Turkey, Australia, Chile, Brazil, Japan, Colombia, China, United Kingdom, Mexico, Peru
Aura Biosciences

Recruiting

A Phase 3 Randomized, Masked, Controlled Trial to Evaluate Efficacy and Safety of Belzupacap Sarotalocan (AU-011) Treatment Compared to Sham Control in Subjects With Primary Indeterminate Lesions or Small Choroidal Melanoma (CoMpass)

Ocular Melanoma | Uveal Melanoma | Choroidal Melanoma | Indeterminate Lesions

United States, Australia, United Kingdom
AbbVie

Recruiting

A Study to Assess Adverse Events, Change in Disease Activity, and How Intravenous and Subcutaneous Risankizumab Moves Through the Body of Pediatric Participants With Moderately to Severely Active Crohn's Disease

Crohn's Disease

United States, Korea, Republic of, Taiwan, Israel, Switzerland, United Kingdom, Puerto Rico
University of Leicester
Guy's and St Thomas' NHS Foundation Trust; Sheffield Teaching Hospitals NHS... and other collaborators

Recruiting

Study on Optimal Temperature During Cardiopulmonary Bypass (THERMIC-4) (THERMIC-4)

Cardiovascular Diseases | Ischemic Heart Disease | Valvular Heart Disease | Surgery-Complications

United Kingdom
EusaPharma (UK) Limited
University of Sheffield (ScHARR); KMC Health Care; Castleman Disease Collaborative...

Not yet recruiting

Producing a Novel Symptom Burden Scale for People Living With Idiopathic Multicentric Castleman Disease (ISBUS)

Idiopathic Multicentric Castleman's Disease
Sheffield Teaching Hospitals NHS Foundation Trust

Recruiting

Traditional Dietary Advice Vs. Mediterranean Diet in IBS

Irritable Bowel Syndrome

United Kingdom
Sanofi
Regeneron Pharmaceuticals

Recruiting

A Study of Long-term Effect of Dupilumab on Skin Barrier Function in Pediatric Participants With Atopic Dermatitis (PELISTAD-EX2)

Dermatitis Atopic

United States, United Kingdom

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