Search clinical trials for: Synthetic Lethality

Total 1317 results

Servier Bio-Innovation LLC
Institut de Recherches Internationales Servier

Recruiting

S095035 in Adult Participants With Advanced or Metastatic Solid Tumors With Deletion of the Methylthioadenosine Phosphorylase (MTAP) Gene

MTAP-deleted Solid Tumors

Australia, United States
Sir Mortimer B. Davis - Jewish General Hospital

Not yet recruiting

Niraparib in High-grade Endometrial Cancer Trial (NIREC)

Endometrial Cancer | Uterine Neoplasm | Serous Adenocarcinoma
Mirati Therapeutics Inc.

Recruiting

Phase 1/2 Study of MRTX1719 in Solid Tumors With MTAP Deletion

Pancreatic Adenocarcinoma | Solid Tumor | Non Small Cell Lung Cancer | Mesothelioma | Advanced Solid Tumor | Malignant Peripheral Nerve Sheath Tumors

United States
IDEAYA Biosciences

Recruiting

Study of IDE397 in Participants With Solid Tumors Harboring MTAP Deletion

Solid Tumor

United States, Taiwan, Korea, Republic of, France, Spain, Australia, Germany
Sierra Oncology LLC - a GSK company

Completed

A Phase 1/2 Trial SRA737 in Combination With Gemcitabine and Cisplatin or Gemcitabine Alone in Advanced Cancer Subjects

Advanced Solid Tumors

Spain, United Kingdom
Sierra Oncology LLC - a GSK company

Completed

A Phase 1/2 Trial of SRA737 in Subjects With Advanced Cancer

Advanced Solid Tumors or Non-Hodgkin's Lymphoma (NHL)

United Kingdom
Umm Al-Qura University

Recruiting

"Comparative Effect of Different Drugs Used to Tr€at Patients in Rheumatoid Arthritis Saudi Database (RASD)"

Rheumatoid Arthritis RA
Women's Hospital School Of Medicine Zhejiang University

Recruiting

Prospective Study for Endometrial Carcinoma and Hyperplasia in Childbearing-age Women

Endometrial Hyperplasia | Endometrial Cancer Stage I

China
Chulalongkorn University

Not yet recruiting

"Quick-starting" of a Quadriphasic Contraceptive Pills, 1 - 3 mg Estradiol Valerate/ 2 - 3 mg Dienogest VS 20 mcg Ethinylestradiol/75 mcg Gestodene Focusing on Ovulation Inhibition

Ultrasound Finding: Ovulation Inhibition, Ovarian Activities | Cervical Mucus | Serum Hormonal Profile
Chulalongkorn University

Not yet recruiting

"Quick-starting" of a New Combined Hormonal Contraceptive Pills, 15 mg Estetrol/3 mg Drospirenone VS 20 mcg Ethinylestradiol/75 mcg Gestodene Focusing on Ovulation Inhibition

Ultrasound Finding: Ovulation Inhibition, Ovarian Activities | Cervical Mucus | Serum Hormonal Profile
Leiden University Medical Center
Karolinska Institutet; Children's Investment Fund Foundation; Women on Waves

Not yet recruiting

Efficacy, Safety, and Acceptability of Mifepristone 50 mg Once-weekly as a Contraceptive (WOMEN)

Female Contraception

Netherlands
Incyte Corporation

Recruiting

A Study to Evaluate the Drug Interaction Between Povorcitinib and the Oral Contraceptive Levonorgestrel/Ethinyl Estradiol in Healthy Adult Females

Healthy Participants

United States
Rambam Health Care Campus

Not yet recruiting

Oxytocin in Multiparous Women

Pregnancy Related
Histograft Co., Ltd.
Petrovsky National Research Center of Surgery

Recruiting

Comparative Study of Gene-Activated Bone Substitute "Histograft" for Lumbar and Cervical Spinal Fusion

Spinal Stenosis | Cervical Disc Disorder With Radiculopathy | Biomechanical Lesion, Unspecified | Lumbar and Other Intervertebral Disc Disorders With Radiculopathy

Russian Federation
Xiao Wang

Recruiting

Assessment of the Improvement in Cognitive Levels of Postmenopausal Depression Patients by Estrogen

Estrogen | Postmenopausal Depression

China
AbbVie

Recruiting

A Study to Assess the Safety and Efficacy of Oral Armour Thyroid Compared to Synthetic T4 for the Treatment of Primary Hypothyroidism in Adult Participants

Hypothyroidism

United States
Yale University
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Not yet recruiting

Oral Contraceptive Pill (OCP) Pharmacogenomics

Contraception | Pharmacogenomic Drug Interaction

United States
Chinese PLA General Hospital

Recruiting

Allogeneic TRAC Locus-inserted CD19-targeting STAR T Cell Therapy in r/r B-NHL

Non-hodgkin Lymphoma,B Cell

China
ViiV Healthcare

Recruiting

A Study to Investigate the Potential Drug-Drug Interaction Between VH4524184 and Oral Contraceptive (Loestrin) in Healthy Adult Female Participants

HIV Infections

United States
InnovaGyn, Inc.
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Recruiting

Phase II Study of Ovulation in Obese Women

Pregnancy Prevention

United States
NextFertility
SINAE SL

Not yet recruiting

Comparison of Two PPOS Models for Pituitary Suppression

Infertility, Female | Fertility Disorders

Spain
Minia University

Not yet recruiting

Naturally Banded Versus Synthetic Banding of Sleeve Gastrectomy

Obesity, Morbid
NorthShore University HealthSystem
Pfizer

Not yet recruiting

Phenotyping of Idiopathic Pelvic Pain With Real-time Uterine Imaging and Relugolix-Combination Therapy Treatment

Pelvic Pain

United States
Evangelisches Klinikum Köln Weyertal gGmbH
University of Cologne

Recruiting

Biological Mesh Versus Synthetic Mesh in Interdisciplinary RRP With SCP (BioSynIRS)

Pelvic Organ Prolapse | Intestinal Obstruction | Rectal Prolapse

Germany
Bio-innova Co., Ltd

Not yet recruiting

Desogestrel Tablets (0.075 mg) Relative to Originator Desogestrel Tablets (0.075 mg)

Healthy Subjects
Ohio State University Comprehensive Cancer Center

Recruiting

Evaluating the Impact of Synthetic Cooling Agents in Combustible Cigarettes on Smoking Perceptions and Use

Cigarette Smoking-Related Carcinoma

United States
Ohio State University Comprehensive Cancer Center
National Cancer Institute (NCI)

Not yet recruiting

Perceptions of E-Cigarettes and Synthetic Cooling Agents, The ICE Study (ICE)

Exposure | Abuse Tobacco

United States
Novo Nordisk A/S

Recruiting

A Research Study Looking at How the Compound NNC0194-0499 Works With Birth Control Pills in Women Not Able to Bear Children.

Healthy Volunteers (Non-alcoholic Steatohepatitis)

Austria
University Hospital, Ghent

Not yet recruiting

PPOS (Progestin Primed Ovarian Stimulation) and Corifollitropin Alfa (CFA) Cross-over Study

Quality of Life | Ovarian Stimulation | Preimplantation Genetic Testing | Fertility Preservation
W.L.Gore & Associates

Not yet recruiting

Clinical Outcomes of the Gore Synthetic Cornea Device

Corneal Opacity
Lori Gawron
Planned Parenthood Association of Utah

Recruiting

Etonogestrel (ENG) Implant Insertion for Emergency Contraception With Oral Levonorgestrel (LNG) vs Placebo

Emergency Contraception

United States
Soligenix

Recruiting

HyBryte (Synthetic Hypericin) Versus Valchlor (Mechlorethamine) in the Treatment of CTCL

Cutaneous T-Cell Lymphoma/Mycosis Fungoides

United States
M3 Health
Universidade Estadual Paulista Júlio de Mesquita Filho

Recruiting

Plenum® Osshp in Maxillary Sinus Elevation Surgery

Oral Surgical Procedures

Brazil
University of Erlangen-Nürnberg Medical School

Not yet recruiting

Clinical Feasibility of Brain Radiotherapy Using Synthetic CTs in an MRI-only Workflow

Brain Tumor, Primary | Brain Tumor - Metastatic

Germany
Memorial Sloan Kettering Cancer Center
Astellas Pharma US, Inc.; Corcept Therapeutics; Breast Cancer Research Foundation

Recruiting

A Study of Enzalutamide, Enzalutamide in Combination With Mifepristone, or Chemotherapy in People With Metastatic Breast Cancer

Metastatic Breast Cancer

United States
Karex Industries Sdn. Bhd.
Essential Access Health; Match Research; Sigma3 Services SARL

Recruiting

Evaluation of Synthetic Nitrile Male Condom Compared to Standard Latex Male Condom

Sexually Transmitted Diseases

United States, South Africa
Spital Thurgau AG

Recruiting

Patch Study (Patch-augmented Rotator Cuff Repair)

Rotator Cuff Tears

Switzerland
Scripps Health
North Park Podiatry

Not yet recruiting

Comparing Wound Complication Following TMA With Aid of Electrospun Fiber Matrix

Amputation | Wound; Foot | Wound Complication
Maastricht University

Not yet recruiting

Brain Activity Under the Influence of JWH

Neurotransmission During JWH Intoxication
Arch Therapeutics

Recruiting

Use of AC5® Advanced Wound System in the Treatment of Diabetic Foot Ulcers

Diabetic Foot Ulcer | Non-healing Wound

United States
M3 Health
São Paulo State University

Not yet recruiting

Guided Bone Regeneration Using Polydioxanone (PDO) Membrane in Sockets After Tooth Extraction

Surgery, Oral
Tanta University

Not yet recruiting

Effect of Hebal and Synthetic Medicamentss on Enterococcus Feacalis

Effective Intracanal Medicaments Against Enterococcus Faecalis
Wake Forest University Health Sciences

Not yet recruiting

Randomized Controlled Trial (RCT) Umbilical Hernia Repair (UHR) Absorbable vs Non-absorbable Synthetic Mesh

Umbilical Hernia

United States
University of California, San Francisco
National Institute on Drug Abuse (NIDA)

Not yet recruiting

Comparative Pharmacokinetics and Pharmacodynamics of Synthetic Nicotine

Nicotine Dependence | Nicotine Vaping

United States
Brigham and Women's Hospital

Recruiting

Project 1: Self-Triage by 2D Full-field Digital Mammography or Synthetic Images

Breast Cancer Screening

United States
University of Central Lancashire
Imperial College London

Not yet recruiting

Comparison of the Use of Natural and Synthetic Bone Substitutes in Dental Implants (BSNS)

Alveolar Ridge Augmentation

United Kingdom
Ryazan State Medical University

Recruiting

Efficacy and Safety of the Regulatory Polypeptides in Patients With Peripheral Atherosclerosis.

Peripheral Arterial Occlusive Disease

Russian Federation
Oregon Health and Science University
Vanderbilt University Medical Center

Not yet recruiting

Heavy Menstrual Bleeding Progestin Treatment in Bleeding Disorders Study (HMB-BD)

Bleeding Disorder | Von Willebrand Diseases | Heavy Menstrual Bleeding
Azienda Socio Sanitaria Territoriale degli Spedali...

Recruiting

Evaluation of the Efficacy of Addition of Progesterone to Standard Chemotherapy in Adrenocortical Carcinoma (ACC) (PESETA)

Adrenocortical Carcinoma

Italy
Karex Industries Sdn. Bhd.
University of Witwatersrand, South Africa; Essential Access Health; Sigma3 Services...

Recruiting

Evaluation of 2 Synthetic Nitrile Male Condoms Compared to a Standard Latex Male Condom

Sexually Transmitted Diseases

United States, South Africa

Search clinical trials for: Synthetic Lethality

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in United Kingdom

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations