Search clinical trials for: cochlear synaptopathy

Total 463 results

Neuracle Science Co., LTD.
Samsung Medical Center; Korea University Anam Hospital; Severance Hospital

Recruiting

A Phase 1b/2a, Study Evaluating the Safety, PK/PD and Efficacy of NS101 in Healthy Volunteers and SSNHL Patients

Sudden Sensorineural Hearing Loss | Seneorineural Deafness

Korea, Republic of
University Ghent
University Hospital, Ghent

Recruiting

Evaluation of the CochSyn Test Prototype to Measure Cochlear Synaptopathy (EarDiTech)

Hearing Loss, Sensorineural | Cochlear Hearing Loss | Cochlear Synaptopathy

Belgium
Pipeline Therapeutics, Inc.

Completed

Phase I/IIa Study Evaluating Safety and Efficacy of an Intratympanic Dose of PIPE-505 in Subjects With Hearing Loss

Sensorineural Hearing Loss

United States
Cochlear
Avania; QbD Clinical

Not yet recruiting

Performance and Hearing-related Outcomes in Adults Implanted With the CI622D Dexamethasone-eluting Cochlear Implant Compared to Those Implanted With a Standard Cochlear Implant (CI622) (DETECT)

Hearing Loss, Sensorineural | Hearing Loss, Bilateral | Hearing Loss, Cochlear | Hearing Loss, Bilateral Sensorineural

France, United Kingdom, Australia, Germany
Institut Pasteur
Institut de l'Audition

Not yet recruiting

MeasurIng and Restoring Auditory Awareness for Cochlear Implant Listeners in noisE (MIRACLE)

Cochlear Hearing Loss

France
Assistance Publique - Hôpitaux de Paris
Advanced Bionics AG

Not yet recruiting

Investigation of Sky Automatic Technologies in Pediatrics (SKY-MARVEL)

Hearing Loss

France
Restorear Devices LLC
University of Miami; National Institute on Deafness and Other Communication...

Not yet recruiting

Investigation of a Device to Deliver Intra-Operative Therapeutic Hypothermia for Hearing Preservation in Cochlear Implantation

Hearing Loss | Cochlear Implants | Cochlear Implantation

United States
Sensorion

Not yet recruiting

A Phase I/II Clinical Trial With SENS-501 in Children Suffering From Severe to Profound Hearing Loss Due to Otoferlin (OTOF) Mutations (AUDIOGENE)

Otorhinolaryngologic Diseases | Ear Diseases | Hearing Disorders | Deafness | Hearing Loss, Sensorineural | Congenital Deafness | DFNB9 | OTOF Gene Mutation

France
MED-EL Elektromedizinische Geräte GesmbH

Not yet recruiting

Longitudinal Outcomes in MED-EL Cochlear Implant Recipients Using a FLEX Electrode (LOTOS)

Cochlear Implants
Sound Pharmaceuticals, Incorporated
Med-El Corporation

Not yet recruiting

SPI-1005 in Adults Receiving Cochlear Implant

Hearing Loss | Cochlear Trauma
Cochlear
Avania

Not yet recruiting

Clinical Performance of the Osia 3 Sound Processor Compared With the Osia 2 Sound Processor in Adult Osia Implant Users (RECONNECT)

Hearing Loss, Conductive | Hearing Loss, Mixed Conductive-Sensorineural

Australia
IRCCS Burlo Garofolo

Recruiting

Hearing Impairment in Children: Pupillometry and Hearing Thresholds Assessment

Hearing Impaired Children

Italy
Advanced Bionics AG

Recruiting

Retrospective Analysis of Long-term Speech Performance in Cochlear Implant Recipients Using Electro-acoustic Stimulation

Cochlear Hearing Loss

Germany
Advanced Bionics AG

Recruiting

Retrospective Analysis of Speech Performance Using the HiRes Ultra and HiRes Ultra 3D Cochlear Implant

Cochlear Hearing Loss

Germany
Cochlear
Avania

Not yet recruiting

Investigating Stimulation Parameter and Electrode Mode Changes on Speech Perception in Experienced Adult Cochlear Implant Recipients (DUAL)

Hearing Loss, Sensorineural

Australia
Cochlear
NAMSA; LWB Consulting

Not yet recruiting

Safety and Effectiveness of Cochlear Implantation in an Expanded Adult Population (ACE)

Hearing Loss, Sensorineural | Hearing Loss, Bilateral

United States
Advanced Bionics AG

Not yet recruiting

Hearing and Structure Preservation Via ECochG (PRESERVE)

Hearing Loss, Sensorineural | Severe-to-profound Hearing Loss

Belgium, United Kingdom, France, Germany, Italy, Poland
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Impact of Robotic Cochlear Implantation on Hearing Performance in Noise (ROBOT-IC-BRUIT)

Severe to Profound Hearing Loss

France
Eye & ENT Hospital of Fudan University
Shanghai Rehabilitation Institute for the Exceptional Children

Recruiting

A Comparative Analysis of Speech Perception Between Cochlear Implant Patients and DFNB9 Patients Receiving Gene Therapy

Hearing Loss | Genetic Disease | Speech Perception

China
Insel Gruppe AG, University Hospital Bern

Recruiting

Status Telemetry for Cochlear Implantations (PATHOS)

Sensorineural Hearing Loss

Switzerland
Sunnybrook Health Sciences Centre

Not yet recruiting

Usability of the Intracochlear Catheter INCAT - a Feasibility Study (INCAT)

Hearing Loss, Sensorineural | Hearing Loss, Cochlear

Canada
Cochlear

Recruiting

Multi-center Study to Examine Changes to the Environment Surrounding the Electrodes in the Cochlea and to Capture the Most Challenging Listening Environments Experienced by Persons With a Cochlear Implant (DICE)

Hearing Loss

Belgium, Australia, Sweden
MED-EL Elektromedizinische Geräte GesmbH

Not yet recruiting

Dexamethasone Eluting Cochlear Implant: a Pivotal Study (CDEX2)

Cochlear Implant

Germany
Cochlear

Recruiting

New Algorithms to Signal Processing for Speech Enhancement in Adult Cochlear Implant Recipients. (PRESENCE-MU)

Hearing Loss

Australia
Cochlear

Recruiting

An Investigation to Validate Speech Perception Assessment for Adult Cochlear Recipients Using a Mobile Research App (VALDE-MU)

Hearing Loss

Australia, United States, Belgium
University Hospital, Grenoble

Recruiting

Predictive Study on Hearing Rehabilitation After Cochlear Implant

Magnetic Resonance Imaging | Hearing Impairment | Cochlear Implant | Tractography | Hearing Rehabilitation

France
Assistance Publique - Hôpitaux de Paris

Recruiting

The Value Electrical Stapedial Reflex Thresholds (eSRTs) Cochlear Implant Mapping (eSRT)

Cochlear Implants | Profound Hearing Loss

France
Hospices Civils de Lyon

Recruiting

Spatial Hearing Rehabilitation in Noise for Bilateral Cochlear Implant Children (KidTrain)

Cochlear Implantation

France
Aalborg University Hospital

Recruiting

Characterisation of Low Frequency Hearing and Vestibular Function in Patients Undergoing Cochlear Implantation

Hearing Loss, Sensorineural | Hearing Loss, Bilateral

Denmark
Regeneron Pharmaceuticals

Recruiting

A Natural History Study in Pediatric Participants With Hearing Loss Due to OTOF, GJB2, or GJB2/GJB6 Mutations (ENSEMBLE)

Congenital Hearing Loss Secondary to Biallelic Mutations in the Otoferlin Gene (OTOF) | Biallelic Mutations in the Gap Junction Beta 2 (GJB2) Gene | Digenic Mutations in GJB2/Gap Junction Beta 6 (GJB6) Genes

United States
University Hospital, Tours

Not yet recruiting

Electrical Impulse Parameters and Neuronal Population in the Cochlear Implanted Patient-PULSE (PULSE)

Sensorineural Hearing Loss
Hospices Civils de Lyon

Recruiting

Cochlear Implantation in the Elderly (RCIVELDO)

Implant | Cochlear

France
MED-EL Elektromedizinische Geräte GesmbH

Recruiting

Comparison in New Cochlear Implanted Subjects of a Tonotopy-based Bimodal Fitting and a Conventional Fitting

Sensorineural Hearing Loss, Bilateral | Bilateral Hearing Loss

France
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

Paraverbal Components of Language and Cochlear Implant

Hearing Loss, Sensorineural

Italy
Tobias Moser

Recruiting

Otoferlin Patient Registry and Natural History Study

Hearing Impairment | Otoferlin-related Auditory Synaptopathy

Germany
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

Rehabilitation Methods of Children With Cochlear Implant (MRSI)

Deafness Neurosensory

Italy
Vanderbilt University Medical Center
National Institute on Deafness and Other Communication Disorders (NIDCD)

Recruiting

Combined Electric and Acoustic Hearing (EAS) in Children and Adults

Hearing Loss | Cochlear Implant

United States
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Analysis of Parental Support in Families Using the LENA After Early Cochlear Implantation (ACLEIC)

Cochlear Implantation | Profound Congenital Deafness

France
MED-EL Elektromedizinische Geräte GesmbH

Recruiting

Comparison in New Cochlear Implanted Subjects of a Tonotopy-based Bimodal Fitting With or Without Synchronization

Sensorineural Hearing Loss, Bilateral

France
Massachusetts Eye and Ear Infirmary
Boston Children's Hospital; University of Washington

Recruiting

Perceptual Consequences of Cochlear Implant Electrode-neuron Interfaces

Deafness

United States
Cochlear
Avania

Recruiting

A Study Evaluating the Application of Hearing Aid Technologies to Signal Processing for Adult Cochlear Implant Recipients (HATSI-MB)

Hearing Loss

Australia
NYU Langone Health
Cochlear Americas

Recruiting

Investigating Auditory Processing in the Users of Auditory Brainstem and Cochlear Implants

Deafness

United States
Guy's and St Thomas' NHS Foundation Trust
University of Nottingham; Imperial College London; University College, London; Cambridge... and other collaborators

Not yet recruiting

BEARS Training Package to Maximise Hearing Abilities in Older Children and Teenagers With Bilateral Cochlear Implants (BEARS)

Hearing Loss | Deafness | Hearing Loss, Sensorineural | Hearing Impaired Children and Adolescents
NYU Langone Health
National Institute on Deafness and Other Communication Disorders (NIDCD)

Recruiting

Evaluating a Noise Reduction Algorithm With Cochlear Implant Users

Hearing Impairment

United States
Regeneron Pharmaceuticals

Recruiting

A Study of DB-OTO, an Adeno-associated Virus (AAV) Based Gene Therapy, in Children/Infants With Hearing Loss Due to Otoferlin Mutations (CHORD)

Congenital Hearing Loss Secondary to Biallelic Mutations of the Otoferlin Gene (OTOF)

Spain, United Kingdom, United States
Neuromed IRCCS
I.R.C.C.S. Fondazione Santa Lucia

Recruiting

Targeting the Gut Dysbiosis to Treat Inflammation-driven Synaptopathy in MS (Pre-Pro-MS)

Patient Participation

Italy
University of North Carolina, Chapel Hill
Med-El Corporation

Recruiting

Cochlear Implants in Young Children With SSD

Hearing Loss | Congenital Hearing Loss | Hearing Loss, Unilateral | Single Sided Deafness | Unilateral Deafness | Deafness One Ear

United States
Cochlear

Recruiting

A Study of Objective Fitting for Focused Multipolar Stimulation (OFIT)

Hearing Loss, Bilateral

Spain
MED-EL Elektromedizinische Geräte GesmbH

Recruiting

Comparison in New Cochlear Implanted Subjects of a Tonotopy-based Fitting With or Without Fine Structure Coding

Sensorineural Hearing Loss, Bilateral

France
Cochlear
Avania; QbD Clinical

Recruiting

Comparing the Performance of a Categorical Loudness Scaling Based Fitting With a Behavioural Fitting in Adults With a Nucleus Cochlear Implant 3 Months Post-activation (CALOS4)

Hearing Loss

Germany, Australia, United States

Search clinical trials for: cochlear synaptopathy

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