Search clinical trials for: open lung strategy

Total 73566 results

University Hospital, Montpellier

Recruiting

Comparison of Two Strategies of One-lung Ventilation in Patients Undergoing Carcinological Lung Resection Surgery. (I-PEEP-THO)

Lung Diseases

France
University Hospital, Clermont-Ferrand

Recruiting

Effects of End-expiratory Positive Pressure Optimization in Intubated Patients With Healthy Lung or Acute Respiratory Distress Syndrome (PEEP-Réa)

ICU Patients | ARDS | Healthy Lung | Positive End-Expiratory Pressure | Alveolar Recruitment Maneuver

France
Massachusetts General Hospital

Recruiting

Open Lung Strategy, Gas Distribution and Right Heart Function in ARDS Patients

Respiratory Distress Syndrome | Mechanical Ventilation Complication | Right Ventricular Dysfunction | ARDS, Human | Right Heart Failure | Lung Injury, Acute | Alveolar Edema

United States
Dokuz Eylul University
Etlik Zubeyde Hanım Women's Health Care, Training and Research Hospital

Completed

Open Lung Strategy During Non-Invasive Respiratory Support of Very Preterm Infants in the Delivery Room (OpenCPAP-DR)

Lung Injury | Respiratory Distress Syndrome in Premature Infant | Non-invasive Ventilation

Turkey
Assistance Publique Hopitaux De Marseille

Completed

Open Lung Protective Ventilation in Cardiac Surgery (PROVECS)

Hypoxemia

France
Centre hospitalier de l'Université de Montréal...

Completed

Impact of an Open Lung Extubation Strategy on Postoperative Pulmonary Complications

Pulmonary Atelectasis | Anesthesia | Complication of Anesthesia

Canada
Centre Hospitalier de Lens

Terminated

The Strategy of "Pulmonary Opening by Titration of Positive End-expiratory Pressure" Means of a Pulmonary Recruitment Maneuver in Patients With Acute Respiratory Distress Syndrome: for Which Patients? (OPPRED)

Respiratory Distress Syndrome, Adult

France
Massachusetts General Hospital

Unknown

Open Lung Strategy in Critically Ill Morbid Obese Patients

Obesity | Pulmonary Atelectasis | Respiratory Insufficiency | Right-Sided Heart Failure | Respiratory Mechanics

United States
Kocaeli University

Completed

Lung Protection Strategy in Open Heart Surgery: Which Tidal Volume is Better 8ml/kg or 6ml/kg

Ventilator-Induced Lung Injury | Ventilator Adverse Event | Lung Injury, Acute

Turkey
Beth Israel Deaconess Medical Center
National Heart, Lung, and Blood Institute (NHLBI)

Completed

EPVent 2- A Phase II Study of Mechanical Ventilation Directed by Transpulmonary Pressures (EPVent2)

Acute Respiratory Distress Syndrome

United States, Canada
Sixth Affiliated Hospital, Sun Yat-sen University

Completed

The PROtective Ventilation Using Open Lung Approach Or Not Trial (PROVOLON)

Respiratory Insufficiency | Postoperative Pulmonary Complications

China
Australian and New Zealand Intensive Care Research...

Terminated

A Multi-centre Trial of an Open Lung Strategy Including Permissive Hypercapnia, Alveolar Recruitment and Low Airway Pressure in Patients With Acute Respiratory Distress Syndrome (PHARLAP)

Acute Respiratory Distress Syndrome

Australia, Ireland, United Kingdom, New Zealand, Saudi Arabia
Fundación para la Investigación del Hospital Clínico...

Unknown

Individualized Perioperative Open-Lung Ventilatory Strategy During One-Lung Ventilation (iPROVE-OLV)

Thoraric Surgery | Surgery Time Expected More Than Two Hours

Spain
Fundación para la Investigación del Hospital Clínico...
Hospital Clinic of Barcelona; Hospital de Manises; Hospital General de Ciudad... and other collaborators

Unknown

Individualized Perioperative Open-lung Ventilatory Strategy With High Versus Conventional Inspiratory Oxygen Fraction (iPROVE-O2). (iPROVE-O2)

Surgical Site Infection | Hyperoxia | Postoperative Complication

Spain
Fundación para la Investigación del Hospital Clínico...
Hospital General Universitario Gregorio Marañon; Germans Trias i Pujol Hospital and other collaborators

Completed

Individualized Perioperative Open Lung Ventilatory Strategy (iPROVE)

Moderated-high Risk of Postoperative Pulmonary Complication | Abdominal Surgery Expected More Than Two Hours

Spain, United States, Argentina, Sweden
Academisch Medisch Centrum - Universiteit van Amsterdam...
European Society of Anaesthesiology

Completed

PROVHILO:Protective Ventilation During General Anesthesia for Open Abdominal Surgery (PROVHILO)

Postoperative Respiratory Complications

United States, Netherlands, Germany, Austria, Belgium, Chile, Croatia, Italy, Spain, United Kingdom
Azienda Ospedaliero, Universitaria Pisana

Unknown

Inflammatory Effects of a Lung Recruitment Manoeuvre

Respiratory Insufficiency | Respiratory Distress Syndrome, Adult

Italy
Hamilton Health Sciences Corporation
Canadian Institutes of Health Research (CIHR)

Completed

Lung Open Ventilation to Decrease Mortality in the Acute Respiratory Distress Syndrome (LOVS)

Acute Respiratory Distress Syndrome

Canada
Basque Health Service
Health Department of the Basque Government

Recruiting

Asthma Crisis in Paediatrics: Impact of a Care Pathway in Primary and Hospital Care

Asthma in Children | Implementation Science | Inappropriate Prescribing

Spain
Beijing Geekgene Technology Co., LTD

Recruiting

a Single-arm, Single-center, Open Clinical Study (GK-01)

Cervical Cancer | Gastric Cancer | Esophageal Cancer | Non-Small Cell Lung Cancer NSCLC | Triple Negative Breast Cancer TNBC

China
Assiut University

Recruiting

Pediatric Video Assisted Thoracoscopic Surgery (VATS) in Management of Empyema (VATS)

Thoracic Empyema

Egypt
Wave Life Sciences Ltd.

Not yet recruiting

A Phase 1b/2a, Open-label Single Ascending Doses and Multiple Ascending Doses Study in Participants With Pi*ZZ AATD (RestorAATion-2)

Alpha-1 Antitrypsin Deficiency
Southeast University, China

Not yet recruiting

Epidemiology and Treatment Strategy of Open Respiratory Phenotype in Critically Ill Patients

Critical Illness | Mechanical Ventilation Pressure High

China
Peking University People's Hospital

Not yet recruiting

Respiratory Function Monitoring of Mechanical Ventilation in Patients With Chest Blunt Injury

Lung Contusion
Rocky Vista University, LLC

Recruiting

Ultrasound Investigation Into Swimming Induced Pulmonary Edema in Open Water Swimming Athletes (SIPE)

Swimming Induced Pulmonary Edema

United States
GlaxoSmithKline

Recruiting

Pragmatic Open - Label Randomized Clinical Trial of FF/UMEC/VI vs Non-ellipta Usual Care ICS-LABA for Adult Participants With Uncontrolled Asthma

Asthma

United States, Canada, Argentina, Australia, Japan, Korea, Republic of, Taiwan
Tongji Hospital

Not yet recruiting

Opioid-Free Combined Anesthesia With Spontaneous Breathing for VATS

Video-assisted Thoracoscopic Lung Surgery；Anesthesia
AstraZeneca

Recruiting

Change in Patient-repOrted Outcomes in COPD Patients Newly Initiated on TRIXEO AEROSPHERE in Real worlD (COnCORD)

Chronic Obstructive Pulmonary Disease (COPD)

Romania
Yong Lin, PhD

Recruiting

Driving Pressure-guided Lung Protective Ventilation (DPV)

Hypoxemia | Ventilator Lung

China
Chisquares Incorporated

Not yet recruiting

Collaborative Open Research Initiative Study (CORIS-1) (CORIS-1)

COVID-19 | Burnout, Professional | Patient Engagement | Artificial Intelligence | Substance Use Disorders | Mental Health Issue | Climate Change | Preventable Disease, Vaccine | Emerging Infectious Disease | Online Education
AstraZeneca
Daiichi Sankyo

Recruiting

Phase III, Open-label, Study of First-line Dato-DXd in Combination With Rilvegostomig for Advanced Non-squamous NSCLC With High PD-L1 Expression (TC ≥ 50%) and Without Actionable Genomic Alterations (TROPION-Lung10)

Non-Small Cell Lung Cancer

Spain, Italy, Japan, Brazil, Taiwan, Korea, Republic of, Australia, Austria, Canada, Poland, United States, Belgium, United Kingdom, Turkey, Hungary, Germany, India
NYU Langone Health
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

RESTORE - Phase II

Maternal Health

United States
AstraZeneca
Daiichi Sankyo

Recruiting

Phase III, Open-label Study of First-line Osimertinib With or Without Datopotamab Deruxtecan for EGFRm Locally Advanced or Metastatic Non-small Cell Lung Cancer (TROPION-Lung14)

Non-small Cell Lung Cancer

Australia, China, Korea, Republic of, Taiwan
Guangdong Provincial People's Hospital

Not yet recruiting

Transfusion in Cardiac Valve Surgery (TICVS)

Valve Heart Disease | Cardiac Surgery With Cardiopulmonary Bypass

China
NaviFUS Corporation
NaviFUS US LLC

Not yet recruiting

Safety and Efficacy of Bevacizumab in Combination With NaviFUS System for the Treatment of Recurrent Glioblastoma Multiforme (rGBM)

Glioma | Neoplasms | Glioblastoma | Neoplasms, Nerve Tissue | Brain Tumor | Glioblastoma Multiforme

United States
Novartis Pharmaceuticals

Recruiting

Open-label, Long-term Safety Study of Secukinumab in Polymyalgia Rheumatica (PMR) (REPLENISH-EXT)

Polymyalgia Rheumatica

Australia
Cairo University

Not yet recruiting

Effect of Rotator Cuff Training on Hand Grip in Adults

Hand Grasp
Centre hospitalier de l'Université de Montréal...
University Health Network, Toronto; Canadian Institutes of Health Research... and other collaborators

Not yet recruiting

Open Lung Protective Extubation Following General Anesthesia (OLEXT-3)

Lung Injury | Anesthesia | Ventilator-Induced Lung Injury | Atelectasis | Intra-abdominal Surgery

Canada
Capital Medical University

Recruiting

Diagnosis and Treatment Strategy Optimization of Severe Pneumonia Based on Multi-omics Data Integration

Severe Community-acquired Pneumonia

China
GB002, Inc.

Not yet recruiting

Open-label Extension Study of Seralutinib in Adult Subjects With PAH (PROSERA-EXT)

Pulmonary Arterial Hypertension

United States
Hipra Scientific, S.L.U
Veristat, Inc.; Asphalion; VHIR

Recruiting

Open-label, Multi-centre, Non-Inferiority Study of Safety and Immunogenicity of BIMERVAX for the Prevention of COVID-19 in Adolescents From 12 Years to Less Than 18 Years of Age.

SARS CoV 2 Infection

Spain
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Impact on Mortality of a Strategy Including Continuous Positive Airway Pressure Plus High Flow Nasal Cannula Oxygen Therapy Versus High Flow Nasal Cannula Oxygen Therapy Alone in Patients With de Novo Acute Hypoxemic Respiratory Failure: a Prospective, Randomized Controlled Trial. (HighCPAP)

De Novo Hypoxemic Acute Respiratory Failure (hARF)
Obafemi Awolowo University Teaching Hospital
Open Philanthropy

Recruiting

ATORvastatin in Pulmonary TUBerculosis (ATORTUB)

Tuberculosis | Pulmonary Tuberculosis | Koch's Disease

Nigeria
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Effect of a Global Simplified Strategy on Thromboembolic Events in Emergency Department Patients With Suspected Pulmonary Embolism (MODS STRATEGY)

Pulmonary Embolism
The Second Affiliated Hospital of Chongqing Medical...
Children's Hospital of Chongqing Medical University; Chongqing Medical Center... and other collaborators

Not yet recruiting

Establishment and Evaluation of Prenatal Prevention and Treatment Strategy for NARDS

Acute Respiratory Distress Syndrome | Respiratory Distress Syndrome, Acute
University of Aarhus
Central Denmark Region

Recruiting

Strategy for Prompt and Effective Thoracentesis in the Emergency Department (SPEEDTAP)

Heart Failure | Pleural Diseases | Pleural Effusion

Denmark
Zai Lab (Shanghai) Co., Ltd.
Zai Lab (US) LLC

Recruiting

An Open-label, Multicenter Study of ZL-1310 in Subjects With Small Cell Lung Cancer

SCLC

United States, China
University Hospital, Rouen

Not yet recruiting

Interest of the Chair Lift Test in the Prognostic Evaluation of Pulmonary Embolism: a Single-center Open Prospective Study (SIT-EP)

Non-severe Pulmonary Embolism
Spirair, Inc

Recruiting

Open-Label Study to Evaluate the Safety and Effectiveness of the Spirair Implant

Nasal Airway Obstruction | Nasal Septal Deviation

United States
University of Malaya

Not yet recruiting

Efficacy and Safety of Automated Closed-loop Ventilator vs Conventional Open-loop Ventilator in the Emergency Department (AVAC)

ARDS | Ventilator-Induced Lung Injury | Mechanical Ventilation Complication | Ventilator Lung

Search clinical trials for: open lung strategy

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