Search clinical trials for: primary or secondary prevention of cardiovascular events

Total 455708 results

Rennes University Hospital

Recruiting

Mechanisms fo Clopidogrel Resistance in Older Adults (CEPAGE) (CEPAGE)

Drug Resistance

France
University Hospital of Ferrara

Recruiting

ConTempoRary Cardiac Stimulation in Clinical practicE: lEft, BivEntriculAr, Right, and conDuction System Pacing (TREEBEARD)

Atrial Fibrillation | Arrhythmias, Cardiac | Left Bundle-Branch Block | Bundle-Branch Block | Ventricular Fibrillation | Ventricular Tachycardia | Ventricular Dysfunction | Atrioventricular Block | Heart Failure, Systolic | Ventricular Arrythmia | Heart Failure，Congestive | Bradyarrhythmia | Heart Arrhythmia | Reduced... and other conditions

Italy
Eli Lilly and Company

Recruiting

A Study to Investigate the Effect of Lepodisiran on the Reduction of Major Adverse Cardiovascular Events in Adults With Elevated Lipoprotein(a) - ACCLAIM-Lp(a)

Elevated Lp(a) | Atherosclerotic Cardiovascular Disease (ASCVD)

Taiwan, United States, Spain, Argentina, China, Italy, Australia, France, Canada, Japan, Belgium, Denmark, Germany, Hungary, Israel, Austria, Korea, Republic of, Brazil, Mexico, Netherlands, Romania, United Kingdom, Greece, Czechia, India, Slovak... and more
Novartis Pharmaceuticals

Not yet recruiting

VictORION-INCLUSION is a Multicenter, Randomized, Open Label, Study of Inclisiran + Usual Care vs Usual Care Alone in an Inclusive and Underrepresented Population at High Risk for or Diagnosed With ASCVD Within a Pragmatic EHR Framework. (V-INCLUSION)

Atherosclerotic Cardiovascular Disease
Novartis Pharmaceuticals

Recruiting

A Study of Inclisiran to Prevent Cardiovascular Events in High-risk Primary Prevention Patients.

Primary Prevention of Atherosclerotic Cardiovascular Disease

United States, China, Italy, Spain, Canada, France, Netherlands, Switzerland, Taiwan, Greece, Thailand, Brazil, India, Hungary, Latvia, Mexico, Israel, Turkey, Argentina, Singapore, Australia, Belgium, Bulgaria, Denmark, Croatia, South Africa and more
Grigore T. Popa University of Medicine and Pharmacy

Not yet recruiting

The Usefulness of Assessing Heart Rate Variability in Patients With Acute Myocardial Infarction (HeaRt-V-AMI)

Myocardial Infarction | Autonomic Dysfunction

Romania
Intermountain Health Care, Inc.

Recruiting

Effectiveness of a Proactive Cardiovascular Primary Prevention Strategy, With or Without the Use of Coronary Calcium Screening, in Preventing Future Major Adverse Cardiac Events (CorCal)

Cardiovascular Primary Prevention Strategy

United States
Hospital Israelita Albert Einstein
Novartis; epHealth

Completed

Real World Evidence Study of Statin Use in Brazil (RWE-Statins)

Myocardial Infarction | Cardiovascular Diseases | Stroke | Hypertension | Diabetes Mellitus | Dyslipidemias

Brazil
Boston Scientific Corporation

Completed

S-ICD® System Post Approval Study

Primary Prevention of Sudden Cardiac Arrest | Secondary Prevention of Sudden Cardiac Arrest

United States
University of Oxford
Bayer; Medical Research Council; Abbott; British Heart Foundation; Solvay Pharmaceuticals and other collaborators

Active, not recruiting

ASCEND: A Study of Cardiovascular Events iN Diabetes

Diabetes Mellitus

United Kingdom
China Academy of Chinese Medical Sciences

Completed

Risk Assessment Model for Ischemic Stroke Endpoint Events

Ischemic Stroke

China
Research and Practical Clinical Center for Diagnostics...

Completed

Possibilities of Perceiving Information on the Primary Prevention of Cardiovascular Diseases in Persons Suffering From Essential Hypertension Through a Social Network (SocialCor)

Prevention, Arterial Hypertension

Russian Federation
Hospital Universitario Reina Sofia de Cordoba

Completed

CORonary Diet Intervention With Olive Oil and Cardiovascular PREVention (CORDIOPREV)

Myocardial Infarction | Diabetes Mellitus | Metabolic Syndrome | Cognitive Decline | Unstable Angina | Malignancy

Spain
Boston Scientific Corporation

Completed

Longitudinal Surveillance Study of the 4-SITE Lead/Header System (LSS of 4-SITE)

Primary Prevention of Sudden Cardiac Arrest | Secondary Prevention of Sudden Cardiac Arrest

United States, Canada, Australia
Medtronic Cardiac Rhythm and Heart Failure

Completed

Improve Sudden Cardiac Arrest Study

Ventricular Arrythmia | Sudden Cardiac Arrest

China, Korea, Republic of, Taiwan, Argentina, Colombia, Singapore, Russian Federation, India, South Africa, Malaysia, United Arab Emirates, Belarus, Brazil, Egypt, Mexico, Tunisia
Duke Kunshan University
Beijing Tiantan Hospital; Duke University; Medical Research Council; Wellcome Trust and other collaborators

Completed

SINEMA Model of Care to Improve the Health of Stroke Patients in Rural China (SINEMA)

Stroke

China
Hadassah Medical Organization

Completed

Community-Based Lifestyle Intervention for Primary and Secondary Prevention of Diabetes in Arab Women in East-Jerusalem

Cardiovascular Diseases | Diabetes | Health Behavior
Pfizer

Terminated

The Evaluation of Bococizumab (PF-04950615; RN316) in Reducing the Occurrence of Major Cardiovascular Events in High Risk Subjects (SPIRE-2)

Cardiovascular Disease

United States, Finland, Netherlands, Spain, Belgium, Germany, Czechia, Switzerland, Denmark, Australia, United Kingdom, Korea, Republic of, Hungary, Israel, Poland, Taiwan, Mexico, Turkey, Ireland, Canada, New Zealand, South Africa, Brazi... and more
MicroPort CRM

Completed

Inappropriate Shock Reduction wIth PARAD+ Rhythm DiScrimination (ISIS-ICD)

Tachycardia

Spain, United States, United Kingdom, France, Japan, Germany, Italy
Bayer

Completed

Epidemiological Study on the Safety of Aspirin in The Health Improvement Network (THIN) (EPISAT)

Stroke | Coronary Heart Disease | Ischemic Heart Disease | Secondary Prevention

United Kingdom
Pfizer

Completed

Randomized Clinical Trial of Bococizumab (PF-04950615; RN316) in Subjects With Hyperlipidemia or Mixed Dyslipidemia at Risk of Cardiovascular Events (SPIRE-LDL)

Hyperlipidemia

United States, Spain, Taiwan, United Kingdom, Canada, Mexico, France, Hungary, Lithuania, Colombia, Romania, Russian Federation
Pfizer

Terminated

The Evaluation of Bococizumab (PF-04950615;RN316) in Reducing the Occurrence of Major Cardiovascular Events in High Risk Subjects (SPIRE-1)

Cardiovascular Disease

Finland, United States, Netherlands, Spain, Korea, Republic of, China, Israel, Belgium, Germany, Australia, Czechia, Taiwan, Denmark, United Kingdom, Hungary, Poland, France, Mexico, Turkey, Canada, New Zealand, Colombia, Switzerland, Irelan... and more
Marilyn MacKay-Lyons
Canadian Institutes of Health Research (CIHR); Heart and Stroke Foundation... and other collaborators

Completed

Program of Rehabilitative Exercise and Education to Avert Vascular Events After Non-disabling Stroke or Transient Ischemic Attack: A Multi-site RCT (PREVENT)

Transient Ischemic Attack | Non-disabling Stroke

Canada
POZEN

Completed

A Study to Evaluate the Incidence of Gastric Ulcers Following Administration of Either PA32540 or Enteric Coated Aspirin 325 mg in Subjects Who Are at Risk for Developing Aspirin-Associated Ulcers

Gastric Ulcer

United States
POZEN

Completed

Study to Evaluate the Incidence of Gastric Ulcers Following Administration of Either PA32540 or Enteric Coated Aspirin 325 mg in Subjects Who Are at Risk for Developing Aspirin-Associated Ulcers

Gastric Ulcer

United States
Creighton University

Completed

Role of Vitamin D in Secondary Prevention of Cardiovascular Events

Cardiovascular Disease

United States
Fundación Centro Nacional de Investigaciones Cardiovasculares...
Ferrer Internacional S.A.; Fundacion Clinic per a la Recerca Biomédica; World... and other collaborators

Completed

Fixed Dose Combination Drug (Polypill)for Secondary Cardiovascular Prevention. (FOCUS)

Myocardial Infarction

Spain, Italy, Argentina, Brazil, Paraguay
AstraZeneca

Terminated

JUPITER - Crestor 20mg Versus Placebo in Prevention of Cardiovascular (CV) Events

Elevated High-sensitivity C-Reactive Protein (hsCRP)

United States, Brazil, Bulgaria, Poland, Russian Federation, South Africa, United Kingdom, Germany, Estonia, Romania, Denmark, Netherlands, Norway, Canada, Mexico, Belgium, Israel, Puerto Rico, Colombia, Argentina, Venezuela, Panama, Urugu... and more
Biotronik France
Biotronik SE & Co. KG

Completed

Observational Study of Patient Comprehension, Perception, Fears and Appreciation Following Home-Monitoring Implementation (Educ@t)

Tachycardia | Defibrillators

France
Guangzhou University of Traditional Chinese Medicine

Unknown

A Nested Case-control Study on the Secondary Prevention of Ischemic Stroke and TIA by Hypertension Health Education Protocol (HHEP): The Post-Stroke Preventive Trial

To Investigate the Relationship Between the Adherence of HHEP After ISTIA and Stroke Recurrence or Cardiovascular Events.

China
Fundación de Ayuda a la Investigación sobre la...

Unknown

Primary Cardiovascular Risk Prevention With Aspirin in Chronic Kidney Disease Patients

Chronic Kidney Disease Stage 3 | Chronic Kidney Disease Stage 4

Spain
Roswell Park Cancer Institute

Withdrawn

Mechanical Stimulation in Preventing Bone Density Loss in Patients Undergoing Donor Stem Cell Transplant

Primary Myelofibrosis | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma and other conditions
Medical University of Vienna
Roche Pharma AG

Completed

Nt-proBNP Guided Primary Prevention of CV Events in Diabetic Patients (PONTIAC)

Coronary Artery Disease | Heart Failure | Diabetes Mellitus

Austria
National Institutes of Health Clinical Center (CC)
National Cancer Institute (NCI)

Completed

T-Cell-Depleted Allogeneic Stem Cell Transplantation After Immunoablative Induction Chemotherapy and Reduced-Intensity Transplantation Conditioning in Treating Patients With Hematologic Malignancies

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Neoplasms

United States
Ramathibodi Hospital
National Health Security Office, Thailand; Ubon Ratchathani Public Health Office... and other collaborators

Unknown

Primary Prevention of Cardiovascular Disease (CVD) in Pre-diabetic & Pre-hypertensive Subjects (PPCVD)

Pre-diabetes | Pre-hypertension

Thailand
Positive Trial Group

Terminated

Primary Prevention of Major Adverse Cardiac Events (MACE) With Standard and Intensive Statin Treatment in Patients With Diabetes: Survival and Cardiovascular Event Assessments (POSITIVE)

Hypertension | Type 2 Diabetes | Hypercholesterolemia

Japan
Johnson & Johnson Pharmaceutical Research & Development...
Ortho-McNeil Neurologics, Inc.

Completed

A Study of the Effectiveness and Safety of Topiramate for the Prevention of Migraine

Migraine | Vascular Headaches
Group Health Centre
Pfizer; McMaster University; Ontario Ministry of Health and Long Term Care; Coalition... and other collaborators

Completed

A Randomized Controlled Trial of a Novel Community-based Primary and Secondary Cardiovascular Prevention Program

Hypertension | Obesity | Diabetes | Hyperlipidemia | Vascular Disease

Canada
AstraZeneca

Completed

Assessment of the Efficacy of Rosuvastatin in Patient Groups With a Dissimilar Risk Profile in an Observational Study (HEROS) (HEROS)

Diabetes | Hypercholesterolemia | Coronary Heart Disease | Peripheral Vascular Disease | Cerebrovascular Accident
University of Nevada, Las Vegas
University of Nevada, Reno

Not yet recruiting

Primary and Secondary Prevention of Type 2 Diabetes Mellitus in Clark County

Pre Diabetes | At Risk for Type 2 Diabetes Mellitus

United States
University of Virginia
American Heart Association

Recruiting

Implementation of Onsite Rapid CYP2C19 Assay for Genotype Guided Dual Antiplatelet Therapy After Acute Ischemic Stroke (ORCA-AIS)

Ischemic Stroke | CYP2C19 Polymorphism

United States
First Affiliated Hospital of Chengdu Medical College

Recruiting

Comparison of Catecholamine Concentrations in Venous Blood During Selective Adrenal Artery Embolization

Primary Aldosteronism | Resistant Hypertension | Secondary Hypertension | Secondary Hypertension to Endocrine Disorders

China
Stichting Hemato-Oncologie voor Volwassenen Nederland
UMC Utrecht; Amsterdam University Medical Centers; The Dutch Network for Cardiovascular...

Not yet recruiting

Prevention of Anthracycline-Induced Cardiac Dysfunction With Dexrazoxane in Patients With Diffuse Large-B Cell Lymphoma (HO170DLBCL)

DLBCL - Diffuse Large B Cell Lymphoma

Netherlands
Cleerly, Inc.
CPC Clinical Research

Recruiting

A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events (TRANSFORM)

Diabetes Mellitus, Type 2 | Metabolic Syndrome | PreDiabetes

United States
Changi General Hospital
Khoo Teck Puat Hospital; Singapore General Hospital; Tan Tock Seng Hospital; Sengkang... and other collaborators

Recruiting

11C-Metomidate PET/CT for Endocrine Hypertension and Characterisation of Adrenal Tumours

Primary Aldosteronism | Primary Aldosteronism Due to Aldosterone Producing Adenoma | Adrenal Tumors

Singapore
Currax Pharmaceuticals

Recruiting

Effect of Naltrexone Hydrochloride ER and Bupropion Hydrochloride ER Combination (Contrave®/Mysimba®) on Major Adverse Cardiovascular Events (MACE) (INFORMUS)

Obesity

United States
UK Kidney Association

Recruiting

National Registry of Rare Kidney Diseases (RaDaR)

Vasculitis | AL Amyloidosis | Tuberous Sclerosis | Fabry Disease | Cystinuria | Focal Segmental Glomerulosclerosis | IgA Nephropathy | Bartter Syndrome | Pure Red Cell Aplasia | Membranous Nephropathy | Atypical Hemolytic Uremic Syndrome | Autosomal Dominant Polycystic Kidney Disease | Cystinosis | Nephronophthisis | BK Nephropathy and other conditions

United Kingdom
Tulane University
National Institutes of Health (NIH)

Recruiting

Church-based Health Intervention to Eliminate Racial Inequalities in Cardiovascular Health (CHERISH)

Cardiovascular Diseases | Hypertension | Diabetes | Hypercholesterolemia

United States
Technical University of Munich

Not yet recruiting

Smartwatches for Detection of Atrial Fibrillation (AFib) in Secondary Prevention of Cryptogenic Stroke (WATCH AFib)

Atrial Fibrillation | Transient Ischemic Attack | Ischemic Stroke, Cryptogenic

Germany
Merck Sharp & Dohme LLC

Recruiting

A Study of MK-0616 (Oral PCSK9 Inhibitor) in Adults With Hypercholesterolemia (MK-0616-013) CORALreef Lipids

Hypercholesterolemia | Familial Hypercholesterolemia

United States, Taiwan, Israel, Argentina, Japan, Korea, Republic of, Turkey, Colombia, China, Mexico, Germany, Italy, South Africa, Spain

Search clinical trials for: primary or secondary prevention of cardiovascular events

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