Search clinical trials for: sedatives

Total 4242 results

Icahn School of Medicine at Mount Sinai

Not yet recruiting

Intrathecal Dexmedetomidine vs Epinephrine

Cesarean Section | Anesthesia, Spinal

United States
Institute of Liver and Biliary Sciences, India
Institute of Liver and Biliary Sciences

Recruiting

Effect of TCI Propofol on Liver Transplant (TCI) Propofol on Intra-operative Usage of Vasopressors in Liver Transplant Recipients.

Liver Transplant Recipients

India
Anqing Municipal Hospital

Recruiting

The Effect of Dexmedetomidine and Esketamine Combined Infusion Quality of Sleep Undergoing Modified Radical Mastectomy

Dexmedetomidine Plus Esketamine Affect Postoperative Sleep Quality

China
Universidad del Desarrollo
Technical University of Munich

Recruiting

Re-evaluation of the Effect Site Model of the PKPD Propofol Eleveld Model (Eleved PD)

Healthy | Surgery

Chile
Theodor Bilharz Research Institute

Recruiting

The Effects of Different Loading Doses of Dexmedetomidine on The Bispectral Index-Guided Propofol Sedation in Patients Undergoing Advanced Upper Gastrointestinal Endoscopic Procedures: A Randomized Control Study

Procedural Sedation | GIT Endoscopy

Egypt
Fujian Provincial Hospital
Fujian Maternity and Child Health Hospital; Fujian Children's Hospital

Not yet recruiting

Intranasal Dexmedetomidine Versus Oral Midazolam Premedication for Postoperative Negative Behavior Changes in Children

Behavior Problem
Baoding First Central Hospital

Not yet recruiting

Ciprofol Versus Propofol in Patients Undergoing Painless Hysteroscopy

Painless Hysteroscopy
Muhammad Ilyas

Not yet recruiting

Impact of Intrathecal vs Intravenous Dexmedetomidine

Nausea and Vomiting, Postoperative
Assiut University

Not yet recruiting

Dexmeditomedine as an Adjuvant to Levobupivacaine in Transversus Thoracis Plane Block on the Management of Post-sternotomy Pain in Open-heart Surgeries

Pain, Postoperative
Sixth Affiliated Hospital, Sun Yat-sen University

Not yet recruiting

Preoperative Oral Midazolam to Postoperative Pain Relief in Sleep Disturbance or Anxiety Patients With Colorectal Cancer (POMPPR)

Pain, Postoperative | Anxiety | Sleep Disturbance | Preoperative | Midazolam

China
Beijing Tiantan Hospital

Not yet recruiting

Perioperative Multimodal Analgesia Protocol for Supratentorial Craniotomy

Postoperative Pain | Analgesia | Supratentorial Brain Tumor
University of Michigan
National Institute of General Medical Sciences (NIGMS)

Recruiting

Investigating Near-Threshold Perception During Anesthetic Sedation

Anesthesia | Propofol | fMRI

United States
University of Ioannina

Recruiting

Opioid-free Anaesthesia in Breast Cancer Surgery

Pain, Postoperative | Breast Cancer | Anesthesia | Pain, Chronic | Cancer Recurrence | Opioid Free Anaesthesia

Greece
Peking University First Hospital
Peking University Shenzhen Hospital

Not yet recruiting

Effect of Dexmedetomidine and Esketamine on Catheter-related Bladder Discomfort

Dexmedetomidine | Esketamine | Urinary Catheter | Catheter-related Bladder Discomfort

China
Benha University

Recruiting

Sevoflurane and Intravenous Anesthesia in Hypospadias Repair

Emergence Delirium | Sevoflurane | Intravenous Anesthesia

Egypt
Haisco Pharmaceutical Group Co., Ltd.

Recruiting

A Multicenter, Open, Controlled, Phase III Clinical Study to Evaluate the Efficacy and Safety of Cipepofol Injection for General Anesthesia in Pediatric Patients Undergoing Elective Surgery

Anesthesia

China
Vertex Pharmaceuticals Incorporated

Not yet recruiting

A Phase 1, Open-label Study Evaluating the Pharmacokinetics and Drug-drug Interaction of VX-993 in Healthy Adults

Pain
Tongji Hospital

Not yet recruiting

Effect of Amobarbital Sodium Combined With Low-dose Propofol on Hemodynamics During Induction and Perioperative Adverse Reactions

Hemodynamics Instability | Amobarbital Sodium
Aswan University

Recruiting

Systemic Versus Local Dexmedetomidine as An Adjuvant to Bupivacaine in Ultrasound Guided Erector Spinae Block

Dexmedetomidine | Erector Spinae Block

Egypt
Aswan University

Recruiting

Fentanyl Versus Dexmedetomidine as an Adjuvant to Bupivacaine in Spinal Anesthesia ; Peritoneal Symptomatic Effects

Dexmedetomidine | Fentanyl

Egypt
Indonesia University

Not yet recruiting

Opioid Free Versus Opioid Balanced Anesthesia in Ophthalmic Surgery

Anesthesia and Analgesia | Anesthesia, Endotracheal
Chung-Ang University Gwangmyeong Hospital

Not yet recruiting

Comparison of Remimazolam and Propofol Combination vs. Propofol in IOM

Neurologic Disorder
Al-Balqa Applied University
Luzmila Hospital

Not yet recruiting

Intermittent Boluses Versus Infusion of Propofol During Gastroscopy

Anesthesia
University of Novi Sad

Recruiting

Intraoperative Dexmedetomidine and Coronary Artery Bypass Graft Surgery

Acute Kidney Injury

Serbia
Etienne Xavier Keller

Recruiting

Effect of Propofol vs. Sevoflurane on Erections During Narcosis In Transurethral Surgery (PENIS)

Erection; Incomplete

Switzerland
Amany Ahmed Eissa

Recruiting

The Efficacy of Thoracic Erector Spinae Plane Block For Perioperative Analgesia in Laparoscopic Bariatric Surgery for Super Obese Patients: Randomized Controlled Trial.

Erector Spinae Plane Block | Bariatric Surgery | Super Obese Patients

Egypt
State University of New York - Upstate Medical...

Not yet recruiting

Intranasal Dexmedetomidine vs. Standard of Care for Emergency Department (ED) Procedural Sedation in the Older Adult

Altered Mental Status
Dr Abdurrahman Yurtaslan Ankara Oncology Training...

Not yet recruiting

The Effectiveness of Bupivacaine and Bupivacaine+Dexmedetomidine Combination in Transversus Abdominis Plane* Block (TAP)

Colorectal Neoplasms | Colorectal Cancer

Turkey
Boehringer Ingelheim

Recruiting

A Study in Healthy Men and Women to Test Whether BI 1569912 Influences the Amount of Repaglinide, Midazolam and Bupropion in the Blood

Healthy

Belgium
Tribhuvan University Teaching Hospital, Institute...

Not yet recruiting

Comparison Between Hyperbaric Bupivacaine With Fentanyl vs. Hyperbaric Bupivacaine With Dexmedetomidine in Reducing Visceral Pain During Cesarean Delivery Under Spinal Anaesthesia

Visceral Pain
Alexandria University

Not yet recruiting

Propofol or Benzodiazepine Combined With Ketamine for Procedural Sedation in Emergency Setting

Procedural Sedation
Beni-Suef University

Recruiting

The Sedative Effects of Dexmedetomidine VS Propofol During Peribulbar Anesthesia in Patients Undergoing Vitrectomy Surgery

Satisfaction | Patient

Egypt
Minia University Hospital

Recruiting

Dexmedetomidine on Postoperative Cognitive Dysfunction and Serum Tau-217 Protein.

Cognitive Impairment

Egypt
Tanta University

Not yet recruiting

Different Doses of Dexmedetomidine in External Oblique Intercostal Plane Block in Splenectomy

Dexmedetomidine | Splenectomy | External Oblique Intercostal Plane Block

Egypt
Yonsei University

Recruiting

Comparison of Remimazolam and Propofol Effect on Oxygen Reserve During Endoscopic Retrograde Cholangiopancreatography

Hepatobiiliary Diseases Requiring Endoscopic Retrograde Cholangiopancreatography

Korea, Republic of
Bayer

Recruiting

A Study to Learn About How BAY2927088 Affects the Level of Midazolam in the Blood When Both Drugs Are Taken Together in Healthy Participants

Healthy Volunteers | Advanced Non-small Cell Lung Cancer | EGFR Mutation | HER2 Mutation

United States
Cairo University

Not yet recruiting

Effect of Dexmedetomidine on Oxygenation and Lung Mechanics

Dexmedetomidine | Drug Use

Egypt
Sanofi

Not yet recruiting

A Study to Investigate Subcutaneous Isatuximab in Combination With Weekly Carfilzomib and Dexamethasone in Adult Participants With Relapsed and/or Refractory Multiple Myeloma (SubQSA)

Plasma Cell Myeloma Refractory
Suez Canal University

Not yet recruiting

Infraclavicular Brachial Plexus Block With Bupivacaine Alone or With Both Dexmedetomidine and Dexamethasone

Upper Extremity Injury
Chung-Ang University Gwangmyeong Hospital
National Research Foundation of Korea

Recruiting

The Effect of Intravenous Versus Volatile Anesthesia on Postoperative Cognitive Dysfunction in Elderly Patients

Postoperative Cognitive Dysfunction

Korea, Republic of
Tanta University

Recruiting

Intraoperative Dexmedetomidine Infusion in Endovascular Intervention for Aneurysmal Subarachnoid Hemorrhage

Dexmedetomidine | Aneurysmal Subarachnoid Hemorrhage | Infusion | Endovascular

Egypt
Martha Sajatovic

Recruiting

Seizure Rescue Medication (RM) as Part of a Comprehensive Epilepsy Self-management Package of Care

Epilepsy

United States
Sohag University

Recruiting

The Efficacy of Dexmedetomidine Versus Labetalol In Providing Controlled Hypotension In Dacryocystorhinostomy SurgeryA Comparative Randomized Prospective Study

Nasolacrimal Duct Obstruction

Egypt
Jemincare

Not yet recruiting

Study to Evaluate the Drug-drug Interaction of JMKX001899 in Healthy Subjects

Solid Tumor, Adult
Ain Shams University

Not yet recruiting

Quality of Recovery After Laparoscopic Cholecystectomy Comparing Opioid Free Analgesia Versus Opioid Free Anesthesia

Pain, Postoperative | Quality of Recovery | Elective Laparoscopic Cholecystectomy

Egypt
Shanghai Zhongshan Hospital

Not yet recruiting

Ciprofol Versus Propofol for Tracheal Intubation in ICU

Emergency Tracheal Intubation in Critically Ill Patients
Tongji Hospital

Not yet recruiting

ED90 of Fospropofol Disodium in Induction and Maintenance of Anesthesia

Elective Surgery

China
Vertex Pharmaceuticals Incorporated

Recruiting

A Phase 1 Study to Evaluate Safety, Tolerability, and Pharmacokinetics (PK) of VX-407 in Healthy Participants

Autosomal Dominant Polycystic Kidney Disease (ADPKD)

United States
Sisli Hamidiye Etfal Training and Research Hospital

Not yet recruiting

The Effects of General Versus Spinal Anesthesia on Postoperative Myocardial Injury

Anesthesia, General | Anesthesia, Spinal | Hypotension During Surgery | Myocardial Injury After Non-cardiac Surgery

Turkey
Al-Azhar University

Not yet recruiting

Comparison Between Ultrasound-Guided Erector Spinae Plane Block Versus Ultrasound-Guided Caudal Injection

Postoperative Pain

Egypt

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