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The Effect of Isometric Exercise and Dry Heat Application on PIVC

14. juli 2026 opdateret af: Hakime Aslan, Inonu University

The Effect of Isometric Exercise and Dry Heat Application on Venous Fullness and Vein Visibility in Cancer Patients: A Randomized Controlled Trial

Purpose: This study was conducted to evaluate the effect of isometric exercise and dry heat application technique on venous fullness and vein visibility in cancer patients.

Design: This study is a randomized controlled trial model. Methods: This study was conducted in the outpatient chemotherapy unit of Malatya Turgut Ozal Medical Center Oncology Hospital, Türkiye. A total of 180 patients were enrolled and randomly allocated using block randomization to an isometric exercise group (n = 60), a dry heat application group (n = 60), or a control group (n = 60). Sample size was determined through power analysis. Data were collected using the "Descriptive Information Form", "Vein Rating Scale" and "Vein Assessment Tool".

Studieoversigt

Detaljeret beskrivelse

Patients admitted to the chemotherapy unit were approached before treatment and informed about the purpose and procedures of the study. Eligibility was assessed according to the inclusion criteria, and written informed consent was obtained from all patients who met the eligibility criteria and voluntarily agreed to participate.

The data collection procedure consisted of the following steps:

Baseline assessment: Participants first completed the socio-demographic section of the Patient Information Form, and the responses were recorded by the researcher.

Pre-intervention vein assessment: A tourniquet was applied to the patient's upper extremity, and vein characteristics were assessed by the nurse using the Vein Rating Scale (VRS) and the Vein Assessment Tool (VAT). During this assessment, no manoeuvres intended to enhance vein visibility (e.g., repeated hand opening and closing, tapping, or slapping the vein) were permitted after tourniquet application. The tourniquet was then removed, and the patient rested for 10 minutes before baseline (pre-test) measurements were recorded.

Intervention: Participants received one of the study interventions according to their assigned group.

Isometric exercise group: Participants were provided with silicone hand exercise balls and instructed to squeeze and release the ball 15-20 times.

Dry heat application group: A chemical gel compress heated to 40 ± 2°C was applied to the selected extremity. Based on previous evidence, maintaining local heat at 40 ± 2°C for at least 5 minutes is sufficient to induce vasodilation.

Control group: Participants received routine peripheral intravenous catheterisation care without any additional intervention.

Post-intervention vein assessment: Immediately after completion of the intervention, a tourniquet was reapplied, and vein characteristics were reassessed by the nurse using the VRS and VAT. These measurements constituted the post-test assessment.

Peripheral intravenous catheterisation: Following the post-test assessment, peripheral intravenous catheterisation was performed by the chemotherapy nurse according to standard clinical practice.

Undersøgelsestype

Interventionel

Tilmelding (Faktiske)

180

Fase

  • Ikke anvendelig

Kontakter og lokationer

Dette afsnit indeholder kontaktoplysninger for dem, der udfører undersøgelsen, og oplysninger om, hvor denne undersøgelse udføres.

Studiesteder

Deltagelseskriterier

Forskere leder efter personer, der passer til en bestemt beskrivelse, kaldet berettigelseskriterier. Nogle eksempler på disse kriterier er en persons generelle helbredstilstand eller tidligere behandlinger.

Berettigelseskriterier

Aldre berettiget til at studere

  • Voksen
  • Ældre voksen

Tager imod sunde frivillige

Ja

Beskrivelse

Inclusion Criteria:

  • Undergoing chemotherapy treatment,
  • Receiving at least 3 cycles of chemotherapy treatment,
  • Not diagnosed with diabetes and/or without peripheral neuropathy,
  • Not receiving antithrombotic therapy,
  • Without bleeding tendency and thrombocytopenia,
  • No deep vein thrombosis,
  • No complications associated with PIVC (such as ecchymosis, hematoma, scarring, edema, infiltration, extravasation and phlebitis),
  • No allergy or sensitivity to heat,
  • No metal prosthesis in the extremity to be heat therapy applied,
  • No limb deformity that would prevent performing isometric exercises,
  • No communication problems,
  • No history of paralysis
  • Patients who volunteered to participate in the study were included.

Exclusion Criteria:

  • Total mastectomy,
  • With peripheral nerve disease,
  • More than 2 peripheral IV catheters applied,
  • Psychiatric illness,
  • People with intellectual disabilities at a level that cannot perceive cognitive functions and
  • Individuals who did not perform or did not want to perform the procedures applied during the research process were not included in the study.

Studieplan

Dette afsnit indeholder detaljer om studieplanen, herunder hvordan undersøgelsen er designet, og hvad undersøgelsen måler.

Hvordan er undersøgelsen tilrettelagt?

Design detaljer

  • Primært formål: Støttende pleje
  • Tildeling: Randomiseret
  • Interventionel model: Crossover opgave
  • Maskning: Enkelt

Våben og indgreb

Deltagergruppe / Arm
Intervention / Behandling
Eksperimentel: Isometric exercise group
Isometric exercise group: Participants were provided with silicone hand exercise balls and instructed to squeeze and release the ball 15-20 times.
articipants were provided with silicone hand exercise balls and instructed to squeeze and release the ball 15-20 times.
Eksperimentel: Dry heat application group
A chemical gel compress heated to 40 ± 2°C was applied to the selected extremity. Based on previous evidence, maintaining local heat at 40 ± 2°C for at least 5 minutes is sufficient to induce vasodilation.
A chemical gel compress heated to 40 ± 2°C was applied to the selected extremity. Based on previous evidence, maintaining local heat at 40 ± 2°C for at least 5 minutes is sufficient to induce vasodilation.

Hvad måler undersøgelsen?

Primære resultatmål

Resultatmål
Foranstaltningsbeskrivelse
Tidsramme
Effects of isometric exercise
Tidsramme: Vein Rating Scale:At baseline (before the intervention) and immediately after the intervention Vein Assessment Tool:At baseline (before the intervention) and immediately after the intervention
Participants were provided with silicone hand exercise balls and instructed to squeeze and release the ball 15-20 times. Vein status is evaluated as the "Vein Rating scale" and the "Vein Assessment Tool". There was a visual analog scale that could be graded from 1 to 10, which evaluated the satisfaction of the nurse with the procedure and the patient's satisfaction with the previous application and the current application. The assessment of satisfaction level was performed after the IV catheter was inserted.
Vein Rating Scale:At baseline (before the intervention) and immediately after the intervention Vein Assessment Tool:At baseline (before the intervention) and immediately after the intervention

Sekundære resultatmål

Resultatmål
Foranstaltningsbeskrivelse
Tidsramme
Effects of dry heat application
Tidsramme: Vein Rating Scale:At baseline (before the intervention) and immediately after the intervention Vein Assessment Tool:At baseline (before the intervention) and immediately after the intervention
Description: A chemical gel compress heated to 40 ± 2°C was applied to the selected extremity. Based on previous evidence, maintaining local heat at 40 ± 2°C for at least 5 minutes is sufficient to induce vasodilation. Vein status is evaluated as the "Vein Rating scale" and the "Vein Assessment Tool". There was a visual analog scale that could be graded from 1 to 10, which evaluated the satisfaction of the nurse with the procedure and the patient's satisfaction with the previous application and the current application. The assessment of satisfaction level was performed after the IV catheter was inserted.
Vein Rating Scale:At baseline (before the intervention) and immediately after the intervention Vein Assessment Tool:At baseline (before the intervention) and immediately after the intervention

Samarbejdspartnere og efterforskere

Det er her, du vil finde personer og organisationer, der er involveret i denne undersøgelse.

Efterforskere

  • Ledende efterforsker: Hakime Aslan, Faculty of Nursing

Publikationer og nyttige links

Den person, der er ansvarlig for at indtaste oplysninger om undersøgelsen, leverer frivilligt disse publikationer. Disse kan handle om alt relateret til undersøgelsen.

Datoer for undersøgelser

Disse datoer sporer fremskridtene for indsendelser af undersøgelsesrekord og resumeresultater til ClinicalTrials.gov. Studieregistreringer og rapporterede resultater gennemgås af National Library of Medicine (NLM) for at sikre, at de opfylder specifikke kvalitetskontrolstandarder, før de offentliggøres på den offentlige hjemmeside.

Studer store datoer

Studiestart (Faktiske)

21. august 2021

Primær færdiggørelse (Faktiske)

15. juli 2023

Studieafslutning (Faktiske)

30. juli 2023

Datoer for studieregistrering

Først indsendt

8. juli 2026

Først indsendt, der opfyldte QC-kriterier

14. juli 2026

Først opslået (Faktiske)

15. juli 2026

Opdateringer af undersøgelsesjournaler

Sidste opdatering sendt (Faktiske)

15. juli 2026

Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier

14. juli 2026

Sidst verificeret

1. juli 2026

Mere information

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