- ICH GCP
- Registro de ensayos clínicos de EE. UU.
- Ensayo clínico NCT00104585
Consortium On Risk for Early-onset Parkinson's Disease (CORE PD)
Genetic Epidemiology of Parkinson's Disease
Descripción general del estudio
Estado
Condiciones
Descripción detallada
Parkinson's disease (PD) is a common, neurodegenerative condition. Although mostly a late-onset disorder, 10 percent of people with PD are reported to develop symptoms before the age of 50. To date, six genes have been found to be associated with PD, however the majority have been found in rare PD 'families'. Some studies have also identified a number of environmental risk factors, such as pesticide use, that appear to increase the risk of PD.
In a previous study, Dr. Karen Marder and her research team found that close family members of people with both early- and late-onset PD have a three-fold increased risk of PD compared to close family members of people without PD.
The purpose of the Consortium On Risk for Early-onset Parkinson's Disease (CORE PD) study is to identify the genetic factors that contribute to the development of early-onset Parkinson's disease, and to understand how these genetic factors interact with other genes and the environment to cause PD.
Participation in the study involves a blood draw (to look for genetic factors associated with PD), questionnaires collecting information on family and medical history, and a neurological examination. In addition participants may be contacted in the future and asked to participate in a more detailed interview. At that time, study investigators will also ask participants for permission to contact family members to invite them to participate in the study.
This research study requires participants to sign a consent form, which states that the research is voluntary and confidential. In addition, since this is a research study, genetic results are not released to participants or their family members now or in the future.
Scientists hope this multi-center study will increase the current knowledge of PD and that the identification of factors that cause PD will lead to better diagnosis and treatment.
Tipo de estudio
Inscripción (Anticipado)
Contactos y Ubicaciones
Estudio Contacto
- Nombre: Helen Mejia-Santana, M.A.
- Número de teléfono: 877-305-2438
- Correo electrónico: research@corepdstudy.org
Ubicaciones de estudio
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California
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Sunnyvale, California, Estados Unidos, 94089
- Activo, no reclutando
- The Parkinson's Institute
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Connecticut
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New Haven, Connecticut, Estados Unidos, 06510
- Activo, no reclutando
- The Institute for Neurodegenerative Disorders
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Illinois
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Chicago, Illinois, Estados Unidos, 60612
- Reclutamiento
- Rush University Medical Center
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Contacto:
- Lucia M. Blasucci
- Número de teléfono: 312-563-2900
- Correo electrónico: Lucia_M_Blasucci@rush.edu
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Glenview, Illinois, Estados Unidos, 60026
- Activo, no reclutando
- Glenbrook Hospital, Evanston
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Maryland
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Baltimore, Maryland, Estados Unidos, 21287
- Activo, no reclutando
- Johns Hopkins Hospital
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Minnesota
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Golden Valley, Minnesota, Estados Unidos, 55427
- Activo, no reclutando
- Struthers Parkinson's Center
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New York
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New York, New York, Estados Unidos, 10032
- Reclutamiento
- Columbia University
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Contacto:
- Helen Mejia-Santana
- Número de teléfono: 877-305-2438
- Correo electrónico: research@corepdstudy.org
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New York, New York, Estados Unidos, 10003
- Activo, no reclutando
- Beth Israel Medical Center
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Pennsylvania
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Philadelphia, Pennsylvania, Estados Unidos, 19104
- Activo, no reclutando
- University of Pennsylvania
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Rhode Island
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Warwick, Rhode Island, Estados Unidos, 02886
- Activo, no reclutando
- Neuro Health
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Tennessee
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Memphis, Tennessee, Estados Unidos, 38136
- Activo, no reclutando
- University of Tennessee Health Science Center
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Wisconsin
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Marshfield, Wisconsin, Estados Unidos, 54449
- Activo, no reclutando
- Marshfield Clinic
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Criterios de participación
Criterio de elegibilidad
Edades elegibles para estudiar
Acepta Voluntarios Saludables
Géneros elegibles para el estudio
Método de muestreo
Población de estudio
Descripción
Inclusion Criteria:
- Any person with Parkinson's disease in the United States whose symptoms began at age 50 or younger and was diagnosed by a neurologist.
Plan de estudios
¿Cómo está diseñado el estudio?
Detalles de diseño
Cohortes e Intervenciones
Grupo / Cohorte |
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1
People with young onset Parkinson's disease and their family members
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Colaboradores e Investigadores
Patrocinador
Investigadores
- Investigador principal: Karen Marder, M.D., M.PH., Columbia University
Fechas de registro del estudio
Fechas importantes del estudio
Inicio del estudio
Finalización primaria (Anticipado)
Fechas de registro del estudio
Enviado por primera vez
Primero enviado que cumplió con los criterios de control de calidad
Publicado por primera vez (Estimar)
Actualizaciones de registros de estudio
Última actualización publicada (Estimar)
Última actualización enviada que cumplió con los criterios de control de calidad
Última verificación
Más información
Términos relacionados con este estudio
Palabras clave
Términos MeSH relevantes adicionales
Otros números de identificación del estudio
- AAAA5609
- R01NS036630 (Subvención/contrato del NIH de EE. UU.)
Esta información se obtuvo directamente del sitio web clinicaltrials.gov sin cambios. Si tiene alguna solicitud para cambiar, eliminar o actualizar los detalles de su estudio, comuníquese con register@clinicaltrials.gov. Tan pronto como se implemente un cambio en clinicaltrials.gov, también se actualizará automáticamente en nuestro sitio web. .