Vasospasm in Pediatric Traumatic Brain Injury (PTBI)

Inclusion Criteria:

1. admission to Duke University Children's Hospital;
2. age 5 days to 15 years;
3. a diagnosis of a TBI with a GCS 3-15;
4. capable of adequate TCD ultrasound examination;
5. and presence of intravenous or arterial access (blood) and/or an EVD for cerebrospinal fluid (CSF) and/or Foley catheter/ability to void unassisted (urine) biomarker collection unless they are excluded based on the exclusion criteria.

Exclusion Criteria:

• the presence of previously diagnosed significant neurodevelopmental delay,
• a diagnosis of non-traumatic intracranial hemorrhage and
• parents/legal guardians who do not speak or understand English.