Dispensing Clinical Trial of Comfilcon A Extended Range Multifocal Lenses
Una sperimentazione clinica di erogazione di lenti multifocali a gamma estesa Comfilcon A
The aim of this study is to validate the clinical of comfilcon A extended range high add center near (CN) multifocal lenses in existing contact lens wearers against the current comfilcon A high add multifocal lenses.
Panoramica dello studio
Stato
Condizioni
Intervento / Trattamento
Descrizione dettagliata
This study is a 13-subject, randomized, prospective, single site, daily wear, single-masked (to the subject), bilateral, 4-day cross-over, dispensing study comparing the comfilcon A extended range multifocal test lens against the comfilcon A multifocal control lens.
Tipo di studio
Iscrizione (Effettivo)
Fase
- Non applicabile
Contatti e Sedi
Luoghi di studio
-
-
Indiana
-
Bloomington, Indiana, Stati Uniti, 47405
- CORL, Indiana University
-
-
Criteri di partecipazione
Criteri di ammissibilità
Età idonea allo studio
Accetta volontari sani
Sessi ammissibili allo studio
Descrizione
Inclusion Criteria:
A person is eligible for inclusion in the study if he/she:
- Has had a self-reported oculo-visual examination in the last two years
- Is 50 years of age or greater and has full legal capacity to volunteer
- Is able to read and understand the informed consent
- Is willing and able to follow instructions and maintain the appointment schedule
- Has a spherical distance contact lens prescription between -1.00 and -5.00D (Diopters) (inclusive)
- Near Add Power requirement of +2.25D or greater
- Has spectacle cylinder 0.75 D in both eyes
- Has normal binocularity (no amblyopia, no strabismus, no habitually uncorrected anisometropia ≥ 2.00D)
- Has monocular best-corrected distance visual acuity of 20/30 or better in each eye
- Has clear corneas and no active ocular disease
- Has not worn gas permeable contact lenses for 1 month prior to the study
Exclusion Criteria:
A person will be excluded from the study if he/she:
- Has never worn contact lenses before
- Has any systemic disease affecting ocular health
- Is using any systemic or topical medications that will affect ocular health
- Has any ocular pathology or abnormality that would affect the wearing of contact lenses
- Is aphakic (i.e. missing their natural lens inside their eye)
- Has uncorrected anisometropia (i.e. difference in the prescription between the eyes) of ≥2.00 D
- Has undergone corneal refractive surgery
- Is participating in any other type of eye related clinical or research study.
Piano di studio
Come è strutturato lo studio?
Dettagli di progettazione
- Scopo principale: Trattamento
- Assegnazione: Randomizzato
- Modello interventistico: Assegnazione incrociata
- Mascheramento: Separare
Armi e interventi
Gruppo di partecipanti / Arm |
Intervento / Trattamento |
|---|---|
|
Sperimentale: comfilcon A Extended Range test lens
Subjects will be randomized to wear either the test or control pair of lens, then cross over to the alternate pair. |
contact lens contact lens |
|
Comparatore attivo: comfilcon A control lens
Subjects will be randomized to wear either the test or control pair of lens, then cross over to the alternate pair. |
contact lens contact lens |
Cosa sta misurando lo studio?
Misure di risultato primarie
Misura del risultato |
Misura Descrizione |
Lasso di tempo |
|---|---|---|
|
Visual Acuity
Lasso di tempo: 4 days
|
Visual acuity was measured at distance, intermediate and near conditions for test and control lens was assessed by LogMAR. |
4 days
|
|
Visual Performance
Lasso di tempo: 4 days
|
Subjective assessment of visual performance for test and control lens is assessed on a scale 0-100, 0=extremely poor vision all of the time and cannot function, 100= excellent vision all of the time). |
4 days
|
Misure di risultato secondarie
Misura del risultato |
Misura Descrizione |
Lasso di tempo |
|---|---|---|
|
Subjective Ratings for Comfort
Lasso di tempo: Baseline
|
Subjective ratings for comfort was assessed for test and control lens on a Scale 0-100, 0=cannot be worn, causes pain, 100=cannot be felt ever). |
Baseline
|
|
Subjective Ratings for Comfort
Lasso di tempo: 4 days
|
Subjective ratings for comfort was assessed for test and control lens on a Scale 0-100, 0=cannot be worn, causes pain, 100=cannot be felt ever). |
4 days
|
|
Subjective Ratings for Dryness
Lasso di tempo: Baseline
|
Subjective ratings for dryness was assessed for test and control lens on a scale 0-100, 0=cannot be worn, extremely dry, 100=no dryness experienced at any time). |
Baseline
|
|
Subjective Ratings for Dryness
Lasso di tempo: 4 days
|
Subjective ratings for dryness was assessed for test and control lens on a scale 0-100, 0=cannot be worn, extremely dry, 100=no dryness experienced at any time). |
4 days
|
|
Lens Handling
Lasso di tempo: 4 Days
|
Subjective ratings for handling (ease of insertion and removal) was assessed for test and control lens on a scale 0-100, 0=very difficult to handle, 100=easy to handle). |
4 Days
|
|
Average Daily Wearing Time
Lasso di tempo: 4 days
|
Average daily wearing time for test and control lens is assessed in hours. |
4 days
|
|
Lens Fit
Lasso di tempo: 4 days
|
Lens fit acceptance (general fit characteristics) is assessed for test and control lens on a 0-4 grading system in 0.25 steps where 0 represented very poor fit. |
4 days
|
|
Bulbar Hyperemia
Lasso di tempo: 4 days
|
Bulbar hyperemia was assessed on a scale of 0-4 and was used in 0.50 steps, with 0 indicating no hyperemia and 4 indicating severe hyperemia. |
4 days
|
|
Limbal Hyperemia
Lasso di tempo: 4 days
|
Limbal hyperemia was assessed on a scale of 0-4 and was used in 0.50 steps, with 0 indicating no hyperemia and 4 indicating severe hyperemia. |
4 days
|
|
Subjective Satisfaction
Lasso di tempo: 4 days
|
Subjective satisfaction for test and control lens was assessed on a scale 0-100, 0=extremely dissatisfied, 100=very satisfied) |
4 days
|
|
Subjective Preference for Near Vision
Lasso di tempo: 4 days
|
Subjective preference for near vision for test and control contact lenses. comfort, vision, handling, satisfaction. |
4 days
|
|
Subjective Preference for Distance Vision
Lasso di tempo: 4 days
|
Subjective preference for distance vision for test and control contact lenses. |
4 days
|
|
Subjective Preference for Intermediate Vision
Lasso di tempo: 4 days
|
Subjective preference for intermediate vision for test and control contact lenses. |
4 days
|
|
Subjective Preference for Overall Vision
Lasso di tempo: 4 days
|
Subjective preference for overall vision for test and control contact lenses. |
4 days
|
|
Subjective Preference for Comfort
Lasso di tempo: 4 days
|
Subjective preference for comfort for test and control contact lenses. |
4 days
|
|
Subjective Overall Lens Preference
Lasso di tempo: 4 days
|
Subjective overall lens preference for test and control contact lenses. |
4 days
|
Collaboratori e investigatori
Sponsor
Investigatori
- Investigatore principale: Pete S Kollbaum, O.D., Indiana University
Studiare le date dei record
Studia le date principali
Inizio studio
Completamento primario (Effettivo)
Completamento dello studio (Effettivo)
Date di iscrizione allo studio
Primo inviato
Primo inviato che soddisfa i criteri di controllo qualità
Primo Inserito (Stimato)
Aggiornamenti dei record di studio
Ultimo aggiornamento pubblicato (Effettivo)
Ultimo aggiornamento inviato che soddisfa i criteri QC
Ultimo verificato
Maggiori informazioni
Termini relativi a questo studio
Termini MeSH pertinenti aggiuntivi
Altri numeri di identificazione dello studio
- CV-16-02
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