The Effects of High Intensity Interval Exercise in Obese
2017年12月13日 更新者:Yokiny Silva、Federal University of Paraíba
The Effects of High Intensity Interval Exercise With 1- and 3- Min Recovery Times in Obese
Obesity is a complex and multifactorial disease.
Excess weight is related to endothelial dysfunction, inflammation and oxidative stress which increases the risk for cardiovascular diseases.
High-intensity interval exercise can release vasodilatory substances and promote increased muscle blood flow.
調査の概要
詳細な説明
This study evaluated the effects of the recovery interval duration (1 vs. 3 min) in high intensity interval exercise (HIIE) on the hemodinamics responses in obese individuals.
Twelve obese subjects (27 ± 3.8 yrs) were evaluated, who underwent three experimental sessions with a randomized crossover design: one control session (no exercise) and two HIIE sessions with the same workload (10 x 1min @92%VO2max / 1[HIIE 1] or 3[HIIE 3] min @0%).
Forearm blood flow (FBF) and blood pressure (BP) were measured before and after the experimental sessions.
Heart rate and relative perceived exertion were assessed during HIIE.
研究の種類
介入
入学 (実際)
12
段階
- 適用できない
参加基準
研究者は、適格基準と呼ばれる特定の説明に適合する人を探します。これらの基準のいくつかの例は、人の一般的な健康状態または以前の治療です。
適格基準
就学可能な年齢
18年~40年 (大人)
健康ボランティアの受け入れ
いいえ
受講資格のある性別
全て
説明
Inclusion criteria for the study were obesity and the conditions of being insufficiently active, non-smokers and without previous history of: heart disease, obstructive or restrictive pulmonary diseases, and orthopedic morbidities.
Fifty-one (51) subjects were evaluated for eligibility, and 39 subjects were excluded after an initial interview since they did not meet the aforementioned inclusion criteria.
研究計画
このセクションでは、研究がどのように設計され、研究が何を測定しているかなど、研究計画の詳細を提供します。
研究はどのように設計されていますか?
デザインの詳細
- 主な目的:処理
- 割り当て:なし
- 介入モデル:単一グループの割り当て
- マスキング:なし(オープンラベル)
武器と介入
参加者グループ / アーム |
介入・治療 |
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実験的:Obese Subjetcs
The subjects were welcomed for a visit to the Laboratory of Studies of Physical Training Applied to Health, where they performed an evaluation of body composition, maximal ergospirometric exercise test, and three experimental sessions (HIIE 1, HIIE 3 and Control) in a random order, which were performed with a 96 h interval between them.
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In the HIIE 1 session, all the subjects performed 10 stimuli of 1 min at high intensity (92% of VO2Max) with passive recovery (without exercise) of 1 min.
In the HIIE 3 session, the subjects performed the same stimulus of the HIIE1, but with passive recovery of 3 min.
Both protocols started with a warm-up of 5 min at 50% of the VO2Peak performed on a T2-100 GE Healthcare® treadmill (Lynn Medical, Wixon, Michigan, USA).
In the control session, participants remained seated for 30 min.
During HIIE 1 and 2, HR and RPE were assessed immediately after stimulus intervals (ten measurements at each HIIE).
In all sessions, the subjects remained in supine position to obtain hemodynamic measurements which were obtained before and at 10 min, 30 min and 60 min after the HIIE and control sessions.
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この研究は何を測定していますか?
主要な結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
---|---|---|
Forearm Blood Flow and Vascular Conductance
時間枠:Up to 2 years
|
Forearm muscular blood flow was obtained through the venous occlusion plethysmography technique (19).
For this, a silicon tube filled with mercury and connected to a low-pressure transducer was placed around the forearm, 5 cm away from the humeral-radial joint, connected to a plethysmograph (Hokanson® / EC6 plethysmograph, Bellevue, Washington, USA).
A cuff was placed around the wrist and another at the upper arm, and the wrist cuff was inflated to a supra-systolic level every 1 min before measurements start.
The arm cuff was inflated above the venous pressure at 10 s intervals for a period of 7 to 8 s.
The increase in tension in the silastic tube reflects the increase in the volume of the forearm, which indicates vasodilation.
The muscle flow wave signal was collected and stored on the WINDAQ DI 200 DATAQ program.
Vascular conductance in the forearm was calculated by the blood flow ratio in the forearm (mL.min-1.100mL-1)
and mean arterial pressure (mmHg) multiplied by 100.
|
Up to 2 years
|
二次結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
---|---|---|
Blood pressure
時間枠:Up to 2 years
|
Blood pressure values were obtained in a non-invasive manner, using an oscillometric method (Dixtal®, DX 2020; Manaus, Amazonas, Brazil).
The occlusive cuff was positioned on the left ankle of the subject and was inflated minute by minute, providing systolic (SBP), diastolic (DBP) and mean (MBP) blood pressure values.
For electrocardiogram (ECG) acquisition, three electrodes were placed on the thorax of the subjects in the bipolar position and DII derivation.
After pre-amplification of the ECG signal, a conversion from analog to digital was performed, and later stored in a computer and processed by the WINDAQ DI-200 program (WinDaq DI-200, Akron, Ohio).
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Up to 2 years
|
Heart rate
時間枠:Up to 2 years
|
Heart rate was monitored throughout the exercise session using a Polar RS800CX monitor (Polar®, Kempele, Finland).
|
Up to 2 years
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協力者と研究者
ここでは、この調査に関係する人々や組織を見つけることができます。
捜査官
- スタディディレクター:Maria do Socorro B Santos, Ph.D.、Federal University of Paraiba
研究記録日
これらの日付は、ClinicalTrials.gov への研究記録と要約結果の提出の進捗状況を追跡します。研究記録と報告された結果は、国立医学図書館 (NLM) によって審査され、公開 Web サイトに掲載される前に、特定の品質管理基準を満たしていることが確認されます。
主要日程の研究
研究開始 (実際)
2016年6月5日
一次修了 (実際)
2016年12月20日
研究の完了 (実際)
2017年1月30日
試験登録日
最初に提出
2017年2月20日
QC基準を満たした最初の提出物
2017年12月13日
最初の投稿 (実際)
2017年12月19日
学習記録の更新
投稿された最後の更新 (実際)
2017年12月19日
QC基準を満たした最後の更新が送信されました
2017年12月13日
最終確認日
2017年12月1日
詳しくは
この情報は、Web サイト clinicaltrials.gov から変更なしで直接取得したものです。研究の詳細を変更、削除、または更新するリクエストがある場合は、register@clinicaltrials.gov。 までご連絡ください。 clinicaltrials.gov に変更が加えられるとすぐに、ウェブサイトでも自動的に更新されます。
HIIE 1の臨床試験
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University Hospital, Clermont-FerrandLaboratory of metabolic adaptation to exercise under Physiological and Physiopathological...わからない
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Shu-Cheng Lin募集
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Janssen Research & Development, LLC完了