心不全-USB: 予測と進行 (HF-USB)
This retrospective cohort study is to identify triggers of heart failure (HF) development and drivers of HF progression as well as the underlying cardiac disease (phenotype) to identify patients at risk and predict the clinical course of the disease. Data of patients who were hospitalized during the years 2010-2023 with acute coronary syndrome (ACS) and/ or with acute heart failure (AHF) will be collected and analyzed. In a subgroup cohort efficacy and safety of digoxin in patients with acute heart failure triggered by tachyarrhythmia will be evaluated.
調査の概要
研究の種類
入学 (推定)
連絡先と場所
研究連絡先
- 名前：Christian Müller, Prof. Dr.
- 電話番号：0041 6132 86 549
- メール：Christian.mueller@usb.ch
研究連絡先のバックアップ
- 名前：Fiona Nafaa, MD
- 電話番号：+41 61 32 87747
- メール：fiona.nafaa@usb.ch
研究場所
-
-
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Basel、スイス、4031
- 募集
- Cardiology, University Hospital Basel
-
コンタクト：
- Christian Mueller, Prof. Dr.
- 電話番号：+41 61 32 86 549
- メール：Christian.mueller@usb.ch
-
-
参加基準
適格基準
就学可能な年齢
健康ボランティアの受け入れ
受講資格のある性別
サンプリング方法
調査対象母集団
Patients that were hospitalized at the Universitätsspital Basel/ Switzerland with the diagnosis of ACS or AHF during the years 2010 - 2023
説明
Inclusion Criteria:
- Patients hospitalized with a primary diagnosis of ACS
- Patients hospitalized with a primary or secondary diagnosis of AHF
Exclusion Criteria:
- Existence of a documented statement of the patient against the scientific use of clinical data
研究計画
研究はどのように設計されていますか？
デザインの詳細
- 観測モデル：COHORT
- 時間の展望：RETROSPECTIVE
コホートと介入
グループ/コホート |
介入・治療 |
|---|---|
|
acute coronary syndrome (ACS)
Outcome information (all-cause death, heart failure (HF) hospitalizations) of patients hospitalized with a primary diagnosis of ACS is analyzed. |
data generated by medical review include Medical history, Medications at presentation, during hospitalization and at discharge, New York Heart Association (NYHA) class, Killip class, Electrocardiographic (ECG) data, echocardiographic data, Interventions (Percutaneous Coronary Intervention (PCI), Coronary Artery Bypass Graft (CABG), Implantable Cardioverter Defibrillator (ICD) implantation, Cardiac Resynchronization Therapy (CRT) Implantation), Outcome Information: all-cause death, HF hospitalizations data generated by direct IT export include Anthropometric data (age, sex, height, weight), Vital signs, Laboratory data |
|
acute heart failure (AHF)
Outcome information (all-cause death, heart failure (HF) hospitalizations) of patients hospitalized with a primary or secondary diagnosis of AHF is analyzed. |
data generated by medical review include Medical history, Medications at presentation, during hospitalization and at discharge, New York Heart Association (NYHA) class, Killip class, Electrocardiographic (ECG) data, echocardiographic data, Interventions (Percutaneous Coronary Intervention (PCI), Coronary Artery Bypass Graft (CABG), Implantable Cardioverter Defibrillator (ICD) implantation, Cardiac Resynchronization Therapy (CRT) Implantation), Outcome Information: all-cause death, HF hospitalizations data generated by direct IT export include Anthropometric data (age, sex, height, weight), Vital signs, Laboratory data |
この研究は何を測定していますか？
主要な結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
|---|---|---|
|
number of all-cause death
時間枠：1 to 8 years after hospitalization
|
number of all-cause death in patients hospitalized with ACS and AHF during the years 2010-2023. |
1 to 8 years after hospitalization
|
|
number of HF hospitalizations
時間枠：1 to 8 years after hospitalization
|
number of new HF hospitalizations in patients hospitalized with ACS and AHF during the years 2010-2023 |
1 to 8 years after hospitalization
|
|
number of cardiovascular death
時間枠：1 to 8 years after hospitalization
|
number of cardiovascular death in patients hospitalized with ACS and AHF |
1 to 8 years after hospitalization
|
|
number of cardiovascular hospitalizations
時間枠：1 to 8 years after hospitalization
|
number of cardiovascular hospitalizations |
1 to 8 years after hospitalization
|
協力者と研究者
捜査官
- 主任研究者：Christian Müller, Prof. Dr.、Cardiology University Hospital Basel
研究記録日
主要日程の研究
研究開始 (実際)
一次修了 (推定)
研究の完了 (推定)
試験登録日
最初に提出
QC基準を満たした最初の提出物
最初の投稿 (実際)
学習記録の更新
投稿された最後の更新 (実際)
QC基準を満たした最後の更新が送信されました
最終確認日
詳しくは
この情報は、Web サイト clinicaltrials.gov から変更なしで直接取得したものです。研究の詳細を変更、削除、または更新するリクエストがある場合は、register@clinicaltrials.gov。 までご連絡ください。 clinicaltrials.gov に変更が加えられるとすぐに、ウェブサイトでも自動的に更新されます。