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Blood Flow Restriction During Nordic Hamstring Exercise in Elite Adolescent Athletes

2026년 7월 13일 업데이트: Idil Esin Unlu, Toros University

Comparison of Hamstring Muscle Oxygenation Responses During Nordic Hamstring Exercise and Blood Flow Restriction Nordic Hamstring Exercise in Elite Adolescent Athletes: A Crossover Experimental Study

This crossover experimental study aims to compare acute hamstring muscle oxygenation responses during Nordic Hamstring Exercise (NHE) and Blood Flow Restriction Nordic Hamstring Exercise (BFR-NHE) in elite adolescent athletes. Participants will complete both exercise conditions in a randomized order separated by a 7-day washout period. Muscle oxygen saturation will be assessed using near-infrared spectroscopy (MOXY), together with total hemoglobin responses, blood lactate concentration, perceived exertion, and exercise performance variables. The findings may improve understanding of the physiological effects of blood flow restriction during eccentric hamstring exercise in adolescent athletes.

연구 개요

상태

모병

정황

개입 / 치료

상세 설명

Hamstring muscles play a crucial role in sprinting, jumping, change-of-direction movements, and other high-intensity athletic activities. Nordic Hamstring Exercise (NHE) is one of the most effective eccentric strengthening exercises for improving hamstring function and reducing the risk of hamstring strain injuries. Recently, blood flow restriction (BFR) training has gained increasing attention because it may enhance metabolic stress and alter muscle oxygenation responses during exercise. However, evidence regarding the acute physiological effects of combining BFR with Nordic Hamstring Exercise in elite adolescent athletes remains limited.

This study aims to compare hamstring muscle oxygenation responses during conventional Nordic Hamstring Exercise and Blood Flow Restriction Nordic Hamstring Exercise in elite adolescent athletes. A prospective crossover experimental design will be used, allowing each participant to complete both exercise conditions and serve as his or her own control. The order of the interventions will be randomized, and the two testing sessions will be separated by a 7-day washout period to minimize potential carryover effects.

Elite adolescent athletes aged 14-18 years who have participated in regular training for at least three years will be recruited. During each testing session, hamstring muscle oxygen saturation (SmO₂) and total hemoglobin (tHb) responses will be continuously monitored using wearable near-infrared spectroscopy (MOXY). Measurements will include baseline SmO₂, minimum SmO₂, delta SmO₂, recovery SmO₂, baseline total hemoglobin, peak total hemoglobin, and delta total hemoglobin. Blood lactate concentration, rating of perceived exertion using the Borg Rating of Perceived Exertion Scale, exercise performance variables, and post-exercise symptoms such as muscle soreness and fatigue will also be recorded.

Nordic Hamstring Exercise will be performed according to a standardized protocol under physiotherapist supervision. During the Blood Flow Restriction Nordic Hamstring Exercise condition, the same exercise protocol will be performed while individualized blood flow restriction is applied to the proximal lower extremity using a pneumatic cuff. The cuff pressure will be individualized based on participant tolerance and safety, and the intervention will be discontinued immediately if any adverse symptoms occur.

The primary objective is to determine whether blood flow restriction alters acute hamstring muscle oxygenation responses during Nordic Hamstring Exercise. Secondary objectives include comparing total hemoglobin responses, blood lactate concentration, perceived exertion, exercise performance, and post-exercise recovery between the two exercise conditions. The findings of this study are expected to improve understanding of the physiological mechanisms of blood flow restriction during eccentric hamstring exercise and provide evidence for its safe and effective use in adolescent athletic populations.

연구 유형

중재적

등록 (추정된)

24

단계

  • 해당 없음

연락처 및 위치

이 섹션에서는 연구를 수행하는 사람들의 연락처 정보와 이 연구가 수행되는 장소에 대한 정보를 제공합니다.

연구 연락처

연구 장소

      • Adana, 터키 (Türkiye)
        • 모병
        • Adana Olympic Preparation Center
        • 연락하다:

참여기준

연구원은 적격성 기준이라는 특정 설명에 맞는 사람을 찾습니다. 이러한 기준의 몇 가지 예는 개인의 일반적인 건강 상태 또는 이전 치료입니다.

자격 기준

공부할 수 있는 나이

  • 어린이
  • 성인

건강한 자원 봉사자를 받아들입니다

예

설명

Inclusion Criteria:

  • Elite adolescent athletes aged 14 to 18 years.
  • Licensed athletes with at least 3 years of regular sports participation.
  • Currently participating in a regular weekly training program.
  • Physically able to complete the Nordic Hamstring Exercise and study testing protocol.
  • Willing to participate in the study.
  • Able to provide written informed consent.
  • For participants younger than 18 years, written informed consent provided by a parent or legal guardian and assent provided by the participant.

Exclusion Criteria:

  • Hamstring injury within the previous 6 months.
  • Lower extremity surgery within the previous 6 months.
  • Current lower extremity pain or musculoskeletal injury that may interfere with exercise performance.
  • Cardiovascular, vascular, neurological, or other medical conditions that may contraindicate blood flow restriction exercise.
  • Presence of skin lesions or conditions preventing placement of the blood flow restriction cuff or MOXY sensor.
  • Inability to complete either exercise condition or follow the study protocol.

공부 계획

이 섹션에서는 연구 설계 방법과 연구가 측정하는 내용을 포함하여 연구 계획에 대한 세부 정보를 제공합니다.

연구는 어떻게 설계됩니까?

디자인 세부사항

  • 주 목적: 다른
  • 할당: 무작위
  • 중재 모델: 크로스오버 할당
  • 마스킹: 없음(오픈 라벨)

무기와 개입

참가자 그룹 / 팔
개입 / 치료
실험적: BFR NHE-NHE
Participants randomized to this sequence will perform conventional Nordic Hamstring Exercise during the first testing session. Following a 7-day washout period, they will perform Nordic Hamstring Exercise with blood flow restriction during the second testing session.
Participants will perform a standardized Nordic Hamstring Exercise protocol under physiotherapist supervision. From a kneeling position with the ankles stabilized, participants will lower the trunk forward in a controlled manner while maintaining alignment of the trunk and hips.
Participants will perform the same standardized Nordic Hamstring Exercise protocol while individualized blood flow restriction is applied using a pneumatic cuff positioned on the proximal lower extremity.
실험적: NHE-BFR NHE
Participants randomized to this sequence will perform Nordic Hamstring Exercise with blood flow restriction during the first testing session. Following a 7-day washout period, they will perform conventional Nordic Hamstring Exercise during the second testing session.
Participants will perform a standardized Nordic Hamstring Exercise protocol under physiotherapist supervision. From a kneeling position with the ankles stabilized, participants will lower the trunk forward in a controlled manner while maintaining alignment of the trunk and hips.
Participants will perform the same standardized Nordic Hamstring Exercise protocol while individualized blood flow restriction is applied using a pneumatic cuff positioned on the proximal lower extremity.

연구는 무엇을 측정합니까?

주요 결과 측정

결과 측정
측정값 설명
기간
Difference in Change in Hamstring Muscle Oxygen Saturation (Delta SmO₂) Between NHE and BFR-NHE
기간: During each exercise session, with the two sessions separated by a 7-day washout period
Hamstring muscle oxygen saturation will be continuously measured using a wearable near-infrared spectroscopy device (MOXY) during conventional Nordic Hamstring Exercise and Blood Flow Restriction Nordic Hamstring Exercise. Delta SmO₂ will be calculated as the difference between baseline SmO₂ and the minimum SmO₂ recorded during each exercise condition. Greater negative change indicates greater muscle deoxygenation.
During each exercise session, with the two sessions separated by a 7-day washout period
Difference in Minimum Hamstring Muscle Oxygen Saturation Between NHE and BFR-NHE
기간: During each exercise session, with the two sessions separated by a 7-day washout period
The minimum hamstring muscle oxygen saturation value (SmO₂, %) recorded during each exercise condition will be obtained using the MOXY near-infrared spectroscopy device. Lower values indicate greater muscle deoxygenation.
During each exercise session, with the two sessions separated by a 7-day washout period
Difference in Hamstring Muscle Oxygen Saturation During Recovery Between NHE and BFR-NHE
기간: Immediately after each exercise session during the recovery period, with sessions separated by a 7-day washout period
Hamstring muscle oxygen saturation (SmO₂, %) will be recorded during the post-exercise recovery period following each exercise condition using the MOXY device.
Immediately after each exercise session during the recovery period, with sessions separated by a 7-day washout period
Difference in Peak Hamstring Total Hemoglobin Between NHE and BFR-NHE
기간: During each exercise session, with the two sessions separated by a 7-day washout period.
Peak total hemoglobin concentration in the hamstring muscle will be recorded during each exercise condition using the MOXY near-infrared spectroscopy device.
During each exercise session, with the two sessions separated by a 7-day washout period.
Difference in Change in Hamstring Total Hemoglobin Between NHE and BFR-NHE
기간: During each exercise session, with the two sessions separated by a 7-day washout period.
Change in total hemoglobin will be calculated as the difference between baseline total hemoglobin and peak total hemoglobin recorded during each exercise condition using the MOXY device.
During each exercise session, with the two sessions separated by a 7-day washout period.
Difference in Post-Exercise Blood Lactate Concentration Between NHE and BFR-NHE
기간: Immediately after each exercise session, with the two sessions separated by a 7-day washout period
Blood lactate concentration will be measured using a portable lactate analyzer following each exercise condition and reported in mmol/L. Higher values indicate a greater acute metabolic response.
Immediately after each exercise session, with the two sessions separated by a 7-day washout period

2차 결과 측정

결과 측정
측정값 설명
기간
Difference in Rating of Perceived Exertion Between NHE and BFR-NHE
기간: Immediately after each exercise session, with the two sessions separated by a 7-day washout period
Perceived exertion will be assessed using the Borg Rating of Perceived Exertion Scale following each exercise condition. Higher scores indicate greater perceived exertion.
Immediately after each exercise session, with the two sessions separated by a 7-day washout period
Difference in the Number of Successfully Completed Nordic Hamstring Exercise Repetitions Between Conditions
기간: During each exercise session, with the two sessions separated by a 7-day washout period
The number of Nordic Hamstring Exercise repetitions completed with the required technique will be recorded during each exercise condition. A higher number indicates better acute exercise performance.
During each exercise session, with the two sessions separated by a 7-day washout period
Difference in Post-Exercise Hamstring Muscle Soreness Between NHE and BFR-NHE
기간: 24 hours after each exercise session
Hamstring muscle soreness will be assessed using an 11-point Numerical Rating Scale ranging from 0, indicating no soreness, to 10, indicating the worst imaginable soreness.
24 hours after each exercise session

공동 작업자 및 조사자

여기에서 이 연구와 관련된 사람과 조직을 찾을 수 있습니다.

스폰서

연구 기록 날짜

이 날짜는 ClinicalTrials.gov에 대한 연구 기록 및 요약 결과 제출의 진행 상황을 추적합니다. 연구 기록 및 보고된 결과는 공개 웹사이트에 게시되기 전에 특정 품질 관리 기준을 충족하는지 확인하기 위해 국립 의학 도서관(NLM)에서 검토합니다.

연구 주요 날짜

연구 시작 (실제)

2026년 7월 1일

기본 완료 (추정된)

2027년 7월 1일

연구 완료 (추정된)

2027년 8월 1일

연구 등록 날짜

최초 제출

2026년 7월 13일

QC 기준을 충족하는 최초 제출

2026년 7월 13일

처음 게시됨 (실제)

2026년 7월 20일

연구 기록 업데이트

마지막 업데이트 게시됨 (실제)

2026년 7월 20일

QC 기준을 충족하는 마지막 업데이트 제출

2026년 7월 13일

마지막으로 확인됨

2026년 7월 1일

추가 정보

이 연구와 관련된 용어

기타 연구 ID 번호

  • 06/101-23.06.2026

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