- ICH GCP
- 미국 임상 시험 레지스트리
- 임상시험 NCT00046657
Longitudinal Study of Neighborhood Predictors of CVD
연구 개요
상세 설명
BACKGROUND:
There are few comprehensive databases that allow for a longitudinal examination of how neighborhood-level factors may interact with individual characteristics to predict incident cases of cardiovascular disease (CVD) and all-cause mortality. This cross-institutional project joins investigators from Karolinska Institutet in Sweden and Stanford University, known for their expertise in immigrant health and social inequalities in CVD.
DESIGN NARRATIVE:
The study examines how neighborhood social characteristics (e.g., neighborhood socioeconomic status (SES), social disintegration, socioeconomic and ethnic segregation, social capital), physical environments (e.g., geocoded assets including goods and services contributing to health such as educational and recreational resources; barriers to health including pollution, industries, waste dumps, criminal activity, alcohol and fast food outlets) and individual factors (e.g., SES, cardiovascular disease {CVD} risk factors, country of birth and social networks) may interrelate to predict CVD [morbidity and mortality] and all-cause mortality. Data will be used from a newly created, comprehensive set of Swedish databases, MigMed and MigSALLS. MigMed (1990-2002) includes data for the entire Swedish population of 6 million women and men aged 25 and older, of whom 600,000 are first generation immigrants. Their addresses have been geocoded, yielding 9,677 neighborhoods, which will be reduced to a smaller number of defined units by cluster analyses. MigMed includes an annual assessment of individual-level sociodemographic and health indicators. Data will also be analyzed from MigSALLS (1988-2002), which includes more in-depth data from face-to-face interviews with a representative sample of approximately 18,000 women and men aged 25-74, of whom 2,000 are first generation immigrants. MigSALLS contains similar individual- and neighborhood-level factors as MigMed, as well as extensive information on factors that may mediate relationships between neighborhoods and CVD outcomes (e.g., CVD risk factors such as smoking, weight, physical activity, and blood pressure). Information from these two datasets will be matched to hospital and death records (300,000 deaths and 140,000 incidence cases of CVD expected between 1988-2002), thus creating one of the largest databases in the world involving men and women from diverse SES levels and countries of origin.
연구 유형
참여기준
자격 기준
공부할 수 있는 나이
건강한 자원 봉사자를 받아들입니다
연구 대상 성별
설명
공부 계획
연구는 어떻게 설계됩니까?
공동 작업자 및 조사자
수사관
- Jan Sundquist, Karolinska Institutet
연구 기록 날짜
연구 주요 날짜
연구 시작
기본 완료 (실제)
연구 완료 (실제)
연구 등록 날짜
최초 제출
QC 기준을 충족하는 최초 제출
처음 게시됨 (추정)
연구 기록 업데이트
마지막 업데이트 게시됨 (추정)
QC 기준을 충족하는 마지막 업데이트 제출
마지막으로 확인됨
추가 정보
이 정보는 변경 없이 clinicaltrials.gov 웹사이트에서 직접 가져온 것입니다. 귀하의 연구 세부 정보를 변경, 제거 또는 업데이트하도록 요청하는 경우 register@clinicaltrials.gov. 문의하십시오. 변경 사항이 clinicaltrials.gov에 구현되는 즉시 저희 웹사이트에도 자동으로 업데이트됩니다. .
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