Dairy Proteins and Postprandial Appetite Regulation and Energy Expenditure (MAES)
研究概览
详细说明
Several studies have shown that a high protein intake is associated with a increased loss of body weight and body fat as compared to a diet with a normal or low protein content. The effect seems to be due to a higher diet induced thermogenesis and increase satiety.
Milk has a high content of proteins. It contains two very different types of protein: whey and casein. Whey is a soluble protein whereas casein clots into the stomach, which delays its gastric emptying and thus probably results in a slower release of amino acids. It is therefore very likely that the two types of protein affect the thermogenesis and appetite regulation differently.
The aim of the present study is to examine the effect of dairy proteins (whey and casein) on postprandial energy expenditure, substrate oxidation and appetite regulation.
The study will have a cross-over design including four meals each including a test drink (milk, casein drink, whey drink or water).
研究类型
注册 (实际的)
阶段
- 不适用
联系人和位置
学习地点
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Copenhagen、丹麦、1958
- Department og Human Nutrition, Life, University of Copenhagen
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参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
描述
Inclusion Criteria:
- healthy males
- body mass index (BMI) 25-30 kg/m2
- 18-50 years
- weight stable
Exclusion Criteria:
- smoker
- regular use of medicine
- elitist athletes
- participation in other intervention studies
学习计划
研究是如何设计的?
设计细节
- 主要用途:预防
- 分配:随机化
- 介入模型:交叉作业
- 屏蔽:单身的
武器和干预
参与者组/臂 |
干预/治疗 |
---|---|
实验性的:milk
skim milk
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Protein drinks with 3.5% protein.
The protein source will be whey, casein or whey and casein (20:80; normal content in the milk).
In the arm with water no protein will be added.
|
实验性的:casein drink
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Protein drinks with 3.5% protein.
The protein source will be whey, casein or whey and casein (20:80; normal content in the milk).
In the arm with water no protein will be added.
|
实验性的:whey drink
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Protein drinks with 3.5% protein.
The protein source will be whey, casein or whey and casein (20:80; normal content in the milk).
In the arm with water no protein will be added.
|
假比较器:water
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Protein drinks with 3.5% protein.
The protein source will be whey, casein or whey and casein (20:80; normal content in the milk).
In the arm with water no protein will be added.
|
研究衡量的是什么?
主要结果指标
结果测量 |
大体时间 |
---|---|
Subjective appetite sensation
大体时间:5 hours
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5 hours
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Energy expenditure
大体时间:5 hours
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5 hours
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Substrate oxidation
大体时间:5 hours
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5 hours
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合作者和调查者
合作者
调查人员
- 首席研究员:Arne Astrup, Dr.、Department of Human Nutrition, Life, University of Copenhagen
研究记录日期
研究主要日期
学习开始
初级完成 (实际的)
研究完成 (实际的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (估计)
研究记录更新
最后更新发布 (估计)
上次提交的符合 QC 标准的更新
最后验证
更多信息
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