Is It Possible to Predict Pre Term Labor by Measuring Cervical Length in the Non-pregnant Uterus?
Working hypothesis and aims:
To investigate the association between cervical length in non-pregnant women, and the risk of premature birth.
The participants will be recruited from the HaEmek Medical Center delivery room registration. Women delivered between 24-37 pregnancy weeks will be allocated to the study group. The investigators will invite them 3 month or more after delivery to ultrasound examination of the cervical length. The participants in the control group will be the women whom term delivery follows by chronological manner to those in study group. Data of the cervucal length will be collected at the time of the examination.
研究概览
地位
条件
详细说明
Women will be invited to undergo an examination in Ultrasound Unit of Department of Obstetrics and Gynecology, HaEmek Medical Center.
Ultrasound examination will be performed using the Voluson E8 device, General Electric.
The cervical length,between the external and internal orifice will be measured using conventional technologies available including: Doppler, three dimensional and two dimensional ultrasound.
研究类型
注册 (实际的)
联系人和位置
学习地点
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Afula、以色列、18101
- Dep. OB/GYN, Emek Medical Center
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参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
取样方法
研究人群
描述
Inclusion Criteria:
- Nonpregnant women aged 18-40 years.
- Singelton last pregnancy.
- Last birth, spontaneous premature (24-37 week)
- Last birth at least 3 months ago.
Exclusion Criteria:
- Presence of uterine malformations.
- Sonographic pathologic findings.
- Technical failure (failed appropiate sonographic visualisation)
- Presence of fetal malformations ( in preterm delivery )
- Presence of comorbidities including diabetes, hypertension, collagen disease, thrombophilia
Presence of risk factors for premature delivery (amniotic fluid infection,
- cervical surgical treatments - conization, polyhydramnios, etc.).
学习计划
研究是如何设计的？
设计细节
- 观测模型：队列
- 时间观点：预期
队列和干预
团体/队列 |
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study group: previous preterm labor
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control group:previous term delivery
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研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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length of the cervix in mm.
大体时间：up to 20 month
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External orifice location is well-defined anatomically and easy for identification .Internal orifice location will be determined by the level of the uterine arteries at both sides of the cervix.
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up to 20 month
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合作者和调查者
调查人员
- 首席研究员：Etty Daniel-Spiegel, MD、HaEmek Medical Center
研究记录日期
研究主要日期
学习开始
初级完成 (实际的)
研究完成 (实际的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (估计)
研究记录更新
最后更新发布 (估计)
上次提交的符合 QC 标准的更新
最后验证
更多信息
此信息直接从 clinicaltrials.gov 网站检索，没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求，请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改，我们的网站上也会自动更新.
早产的临床试验
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University Hospitals Cleveland Medical CenterThe Cleveland Clinic; MetroHealth Medical Center招聘中早产 | 怀孕早产 | 舞会（怀孕） | 怀孕舞会 | PROM，早产（怀孕） | Premat Rupture Membranes Preterm 未指定破裂/分娩之间的时间长度美国