Proprioceptive Postural Control and Chronic Obstructive Pulmonary Disease (COPD)
Proprioceptive weighting changes may explain differences in postural control performance. In addition, the respiratory movement has a disturbing effect on postural balance. Postural balance seems to be impaired in individuals with respiratory disorders. Increased risk of falling is reported in individuals with chronic obstructive pulmonary disease. Besides the essential role of respiration, the diaphragm may also play an important role in the control of the trunk and postural balance.
The aim of the study is to clarify whether proprioceptive postural control is impaired in individuals with chronic obstructive pulmonary disease.
研究概览
研究类型
注册 (预期的)
联系人和位置
学习地点
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Vlaams-Brabant
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Leuven、Vlaams-Brabant、比利时、3000
- Katholieke Universiteit Leuven
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参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
取样方法
研究人群
描述
Inclusion Criteria individuals with chronic obstructive pulmonary disease:
- Age: 40-80 years old
- Spirometry (post-bronchodilator) based diagnosis of COPD (GOLD criteria)
- Willingness to sign the informed consent
Inclusion Criteria healthy controls:
- Age: 40-80 years old
- No COPD (spirometry based: FEV1/FVC ≥ 0.7 and FEV1 > 80%)
- Willingness to sign the informed consent
Exclusion Criteria:
- History of major trauma and/or major orthopedic surgery of the spine, the pelvis or the lower quadrant
- One of the following conditions: Parkinson, multiple sclerosis, stroke, history of vestibular disorder
- Respiratory disorder other than COPD
- α1-antitrypsin deficiency
- Known history of significant inflammatory disease other than COPD
- COPD exacerbation within 4 weeks prior to study
- Lung surgery
- Recent diagnosis of cancer
- Therapy with oral corticosteroids in the last 6 weeks
- Significant cardiovascular comorbidity
学习计划
研究是如何设计的？
设计细节
队列和干预
团体/队列 |
|---|
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chronic obstructive pulmonary disease
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healthy matched controls
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研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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Proprioceptive postural control
大体时间：6 months
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Center of pressure displacement (force plate) in standing in response to local muscle vibration on ankle and back muscles to specifically detect the role of proprioception in postural control.
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6 months
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合作者和调查者
赞助
调查人员
- 首席研究员：Simon Brumagne, PhD、KU Leuven
- 首席研究员：Wim Janssens, MD, PhD、KU Leuven
- 首席研究员：Marc Decramer, MD, PhD、KU Leuven
出版物和有用的链接
研究记录日期
研究主要日期
学习开始
初级完成 (实际的)
研究完成 (实际的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (估计)
研究记录更新
最后更新发布 (估计)
上次提交的符合 QC 标准的更新
最后验证
更多信息
与本研究相关的术语
其他相关的 MeSH 术语
其他研究编号
- 2012_SBrumagne_COPD
- 1.5.104.03, G.0674.09 (其他赠款/资助编号：Research Foundation Flanders (FWO))
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