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Second Young Adult Naturalistic Alcohol Study (YANAS-2)

2020年3月4日 更新者:Yale University

Second Young Adult Naturalistic Alcohol Study (YANAS-2)

This study involves completion of questionnaires, computer-based cognitive tasks and an alcohol drinking session. Participation in this study consists of an initial, in-person screening appointment, 4 brief daily appointments at the research office, an alcohol drinking session at a local bar and a follow-up appointment 1-3 days after the alcohol drinking session.

Participants who are found to be eligible in the screening phase will then complete a daily appointment for 4 days out of a 5-day period (i.e., there will be 1 day out of the 5 on which they will not attend an appointment). Each appointment will last 20 minutes, on average and consist of a questionnaire and computer-based cognitive task. On the day of the fourth appointment, participants will complete an alcohol drinking session. The alcohol drinking session begins at 4pm and lasts until at least midnight.

Participants in this study will be young adults between the ages of 21-25, who regularly drink alcohol and are not currently seeking treatment for alcohol use. Seventy-two participants will complete this study.

研究概览

地位

完全的

研究类型

观察性的

注册 (实际的)

69

联系人和位置

本节提供了进行研究的人员的详细联系信息,以及有关进行该研究的地点的信息。

学习地点

    • Connecticut
      • New Haven、Connecticut、美国、06519
        • Yale University School of Medicine

参与标准

研究人员寻找符合特定描述的人,称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。

资格标准

适合学习的年龄

21年 至 25年 (成人)

接受健康志愿者

有资格学习的性别

全部

取样方法

非概率样本

研究人群

Healthy young adults between the ages of 21-25 years of ago who regularly drink alcohol and are not currently seeking treatment for alcohol.

描述

Inclusion Criteria:

  • Be between the ages of 21-25.
  • Be able to read English and complete study evaluations.
  • Drink alcohol on a regular basis

Exclusion Criteria:

No participant may:

  • Be seeking treatment for alcohol or other addictive behaviors or have been in inpatient or intensive outpatient treatment within the past 12 months.
  • Provide two positive breath alcohol concentration (BAC) readings (i.e., > 0.00%) at any of the following times: in-person screening, a pre-session screening, or at the outset of an alcohol self-administration session. After participants blow their first positive BAC, they will be allowed to reschedule and participate at another time, however if they blow a second positive BAC, they will be excluded from this study and offered referrals for alcohol treatment.
  • Have positive urine screen results at the in-person screening or pre-session screening on the day of an alcohol self-administration session for opiates, cocaine, phencyclidine, amphetamines, methamphetamine, barbiturates, methadone or benzodiazepines.
  • A woman who is pregnant, nursing, or refuses to use a reliable method of birth control.
  • Fail to perform at a normative level at screening on any of the four cognitive and psychomotor tasks administered in this study. Participants must perform within two standard deviations of the mean from the samples in relevant prior studies
  • Perform computer tasks initially administered at baseline in either a random or inordinately slow fashion
  • A body mass index lower than 18.5 or greater than 35.

学习计划

本节提供研究计划的详细信息,包括研究的设计方式和研究的衡量标准。

研究是如何设计的?

设计细节

  • 观测模型:队列
  • 时间观点:预期

队列和干预

团体/队列
Young adult alcohol drinkers
Young adults between the ages of 21-25 who regularly drink alcohol

研究衡量的是什么?

主要结果指标

结果测量
大体时间
Peak estimated blood alcohol concentration
大体时间:During a 3-hour alcohol drinking period
During a 3-hour alcohol drinking period

次要结果测量

结果测量
大体时间
Number of alcoholic drinks consumed
大体时间:During a 3-hour alcohol drinking period
During a 3-hour alcohol drinking period

其他结果措施

结果测量
大体时间
Self-reported drinks per drinking day
大体时间:6- and 12-month follow-ups after alcohol drinking session
6- and 12-month follow-ups after alcohol drinking session
Self-reported frequency of heavy drinking days
大体时间:6- and 12-month follow-up after alcohol drinking session
6- and 12-month follow-up after alcohol drinking session

合作者和调查者

在这里您可以找到参与这项研究的人员和组织。

调查人员

  • 首席研究员:Robert F Leeman, Ph.D.、Yale University

研究记录日期

这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查,以确保它们在发布到公共网站之前符合特定的质量控制标准。

研究主要日期

学习开始

2013年1月1日

初级完成 (实际的)

2015年11月1日

研究完成 (实际的)

2016年10月1日

研究注册日期

首次提交

2013年1月24日

首先提交符合 QC 标准的

2013年1月28日

首次发布 (估计)

2013年1月31日

研究记录更新

最后更新发布 (实际的)

2020年3月6日

上次提交的符合 QC 标准的更新

2020年3月4日

最后验证

2020年3月1日

更多信息

与本研究相关的术语

其他相关的 MeSH 术语

其他研究编号

  • 1209010754
  • R03AA022232 (美国 NIH 拨款/合同)

此信息直接从 clinicaltrials.gov 网站检索,没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求,请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改,我们的网站上也会自动更新.

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