Comparison of Bupivacaine and Exparel for Carpal Tunnel Release
Does Long-Acting Liposomal Bupivacaine Provide Improved Pain Relief Over Bupivicaine Alone in Carpal Tunnel Release?
Carpal tunnel syndrome is one of the most common surgeries performed per year in the United States, accounting for over 600,000 surgeries. The procedure is commonly performed under light sedation and local anesthesia. Bupivicaine, a long acting local anesthetic, has been used to allow extended pain relief for 8-10 hours after carpal tunnel release. Exparel, a liposomal bupivicaine formulation, has been documented to provide pain relief for up to 72 hours post-operatively. By decreasing post-operative pain through the use of a long-acting local anesthetic, the use of narcotic pain medications may be decreased and patient satisfaction scores may increase.
The purpose of this study is to prospectively compare bupivicaine and liposomal bupivicaine with respect to post-operative pain control, narcotic usage, and patient satisfaction after carpal tunnel release.
研究概览
研究类型
阶段
- 不适用
联系人和位置
学习地点
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Pennsylvania
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Pittsburgh、Pennsylvania、美国、15213
- University of Pittsburgh Medical Center
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参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
描述
Inclusion Criteria:
- Patients with carpal tunnel syndrome undergoing surgery
Exclusion Criteria:
- Non english speaking
- Allergy to bupivacaine or exparel
学习计划
研究是如何设计的?
设计细节
- 主要用途:治疗
武器和干预
参与者组/臂 |
干预/治疗 |
---|---|
有源比较器:Bupivacaine
Patients will received 0.5% Bupivacaine subcutaneously for local anesthesia during surgery
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实验性的:Exparel
Patients will received Exparel subcutaneously for local anesthesia during surgery
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研究衡量的是什么?
主要结果指标
结果测量 |
措施说明 |
大体时间 |
---|---|---|
Pain
大体时间:Starting immediately after surgery and then every 8 hours for 10 days
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Pain will be evaluated using an 11-point ordinal scale (0-10)
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Starting immediately after surgery and then every 8 hours for 10 days
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合作者和调查者
研究记录日期
研究主要日期
学习开始
初级完成 (实际的)
研究完成 (实际的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (估计)
研究记录更新
最后更新发布 (估计)
上次提交的符合 QC 标准的更新
最后验证
更多信息
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