New Ultrasound Parameters for Predicting Birthweight (NUPS)
Babies that are either very small or very big have increased perinatal morbidity and mortality. Predicting which babies will fall into these groups is traditionally done with risk assessment and third trimester manual palpation, however neither of these techniques are sensitive and a considerable number of affected pregnancies are missed. This results in stillbirth for small babies or birth trauma for larger ones. Serial scanning in the third trimester can improve detection rates but this is expensive and cannot currently be provided to all NHS patients.
A more sensitive test that can be performed earlier in pregnancy would allow identification of at risk pregnancies allowing for increased monitoring. New three dimensional ultrasound techniques that measure volume and volumetric flow have become available that may allow this to happen. This study proposes to trial newer ultrasound techniques on a cohort of pregnant women. The findings from these scans will then be correlated with actual birth weights at the end of pregnancy to determine the ability of these parameters to act as screening tools for babies at the extremes of size.
研究概览
地位
条件
研究类型
注册 (实际的)
联系人和位置
学习地点
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Manchester、英国、M13 9WL
- Central Manchester University Hospitals NHS Foundation Trust
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参与标准
资格标准
适合学习的年龄
- 孩子
- 成人
- 年长者
接受健康志愿者
有资格学习的性别
取样方法
研究人群
描述
Inclusion Criteria:
- Pregnant women the beginning of pregnancy to term
Exclusion Criteria:
- Pregnancies in women previously affected by unclassfied fetal abnormality
- Multiple pregnancy
学习计划
研究是如何设计的?
设计细节
- 观测模型:队列
- 时间观点:预期
队列和干预
团体/队列 |
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Pregnant mothers
No intervention
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研究衡量的是什么?
主要结果指标
结果测量 |
大体时间 |
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Kidney volume, thigh volume, placental volume, brain volume, final birthweight
大体时间:up to 34-36 weeks pregnancy gestation
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up to 34-36 weeks pregnancy gestation
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合作者和调查者
调查人员
- 首席研究员:Ed Johnstone, MBChB PhD MRCOG、CMFT
研究记录日期
研究主要日期
学习开始
初级完成 (实际的)
研究完成 (实际的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (估计)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
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