Serum CTRP3 and RBP4 Levels in Obesity and Hypertension
研究概览
详细说明
研究类型
注册 (实际的)
参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
取样方法
研究人群
描述
Inclusion Criteria:
- Hypertension not taking antihypertensive medications
- Obesity not taking anti-obese or lipid-lowering medications
Exclusion Criteria:
- Heart failure;
- pregnant or lactating
- diabetes
- thyroid disease
- fractures
- osteoporosis
- tumors;
学习计划
研究是如何设计的?
设计细节
- 观测模型:案例交叉
- 时间观点:横截面
队列和干预
团体/队列 |
---|
NW-NBP group
normal weight and blood pressure subjects
|
NW-HTN group
Normal weight with hypertension subjects
|
OB-NBP group
obese-normal blood pressure subjects
|
OB-HTN group
Obese-hypertension subjects
|
研究衡量的是什么?
主要结果指标
结果测量 |
措施说明 |
大体时间 |
---|---|---|
CTRP3 and RBP4 levels were measured in obesity and hypertension
大体时间:1 year
|
531 subjects were required to fast overnight before the physical examination.Blood pressure was measured three times, each 2 min apart on the upper arm using a mercury sphygmomanometer in a seated, resting position after 10 minutes of rest; the mean of the three measurements was used for the statistical analysis.Weight, height and hip and waist circumference (WC), were measured. BMI was calculated as body weight in kilograms divided by the square of height (m2). WHR was calculated as the waist to hip circumference. Overnight fasting blood samples were collected in tubes containing liquid EDTA; the samples were centrifuged at -4°C and maintained at -80°C until assayed. FBG was assayed using the glucose oxidase method. UA, TC, TG, LDL-C and HDL-C concentrations were determined enzymatically. |
1 year
|
合作者和调查者
调查人员
- 研究主任:Deng Wuquan, PHD、Southwest Hospital, China
出版物和有用的链接
有用的网址
- Implication of Progranulin and C1q/TNF-Related Protein-3 (CTRP3) on Inflammation and Atherosclerosis in Subjects with or without Metabolic Syndrome
- Role of anti-inflammatory adipokines in obesity-related diseases.
- Identification of Adipokine Clusters Related to Parameters of Fat Mass, Insulin Sensitivity and Inflammation
研究记录日期
研究主要日期
学习开始
初级完成 (实际的)
研究完成 (实际的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (估计)
研究记录更新
最后更新发布 (估计)
上次提交的符合 QC 标准的更新
最后验证
更多信息
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