Gray Matters Alzheimer's Disease Prevention Intervention

无干预：控制

无干预

实验性的：Treatment

Health education program; informational website, experiential classes in various help domains, custom smart phone application, and wearable technology

行为的：Health education program

The intervention is a health education program including: informational website, experiential classes, custom smart phone or smart table application, wearable activity monitor, and informal coaching by student researchers to provide moral support for lifestyle behavioral change goals. Participants are not placed on any specific behavioral regimen but instead are encouraged to adopt healthier lifestyle behaviors per the evidence-based health education program, and to attend the experiential classes "cafeteria style" (i.e. based on their individual preferences).

Picture Vocabulary

Picture Vocabulary cognitive test score

Flanker Inhibitory Control and Attention Test

Flanker Inhibitory Control and Attention Test cognitive test score

List Sorting Working Memory Test

List Sorting Working Memory Test cognitive test score

Oral Symbol Digit Test

Oral Symbol Digit Test cognitive test score

Montreal Cognitive Assessment

Montreal Cognitive Assessment test score

Rey Auditory Verbal Learning Test

Rey Auditory Verbal Learning Test score

Controlled Oral Word Association Test

Controlled Oral Word Association Test score

Blood pressure

Systolic and diastolic blood pressure

Body mass index

Height and weight measurement for computing body mass index

Insulin

insulin from venipuncture blood sample

Systemic inflammation

C-reactive protein from venipuncture blood sample

Skin carotenoid status

Biophotonic device that shines a light-emitting diode (LED) light at a site on the palm, to measure the skin carotenoid level in units of Raman counts

Triglycerides

triglycerides from venipuncture blood sample

HDL Cholesterol

High-density lipoprotein from venipuncture blood sample

LDL Cholesterol

Low-density lipoprotein from venipuncture blood sample

Total cholesterol

Total cholesterol from venipuncture blood sample

Depression

Center for Epidemiologic Studies - Depression scale score

Motivation

Situational Motivation Scale score

Sleep Quality

Pittsburgh Sleep Quality Index scale score

Stress

Perceived Stress Scale score

Emotional Support

Emotional Support subscale from the NIH Toolbox measures for social engagement

Friendship

Friendship subscale from the NIH Toolbox measures for social engagement

Hostility

Hostility subscale from the NIH Toolbox measures for social engagement

Loneliness

Loneliness subscale from the NIH Toolbox measures for social engagement

Physical Activity - Moderate

self-report question concerning # minutes per day doing moderate intensity physical activity (per Center for Disease Control definition)

Physical Activity - Vigorous

self-report question concerning # minutes per day doing vigorous intensity physical activity (per Center for Disease Control definition)

Nutrition

Diet History Questionnaire

Readiness for Change

Revised University of Rhode Island Change Assessment (R-URICA) readiness for change scale

Metacognition

Total score from a set of seven items (1=much worse to 5=much better), comparing current memory to how it was three years ago, adapted from a questionnaire of functional ability