Impact of Socioeconomic Inequalities in Transition Between Health, Multimorbidity and Death Amongst Older People
What is the Impact of Socioeconomic Inequalities in the Rates of Transition Between Health, Multimorbidity and Death Amongst Older People in England?
研究概览
详细说明
The association between social inequality and cause-specific mortality and single disease morbidity has been studied extensively. However, it remains unclear whether having two or more chronic diseases concurrently (or 'multimorbidity') plays a role in contributing to the inequalities gap in survival. This is particularly relevant given an ageing population and the trend of a widening in the life expectancy gap across several European countries.
Multimorbidity incidence increases rapidly with age. Estimates of the prevalence of multimorbidity in older people range from 55% to 98%, mainly due to the selection of diseases included, population coverage (hospital, community) and data source (self-reported surveys or clinical records). However, across all studies there is a clear and consistent pattern of higher prevalence rates at older ages, with multimorbidity.
Many aspects of the patient health trajectory remain under-explored. Patient case-mixes are likely to vary across socioeconomic groups, alongside a host of prognostic factors, including the clustering of multiple risk factors, age of onset, and disease presentation, progression and management in the presence of multiple health conditions.
研究类型
注册 (预期的)
联系人和位置
学习地点
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London、英国、WC1 E7H
- University College London
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参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
取样方法
研究人群
描述
Inclusion Criteria:
- Registered with a participating practice that has agreed to data linkage
- Registered with an 'up to standard' participating general practice for at least 1 year
- Aged 45 and over on Jan 1st 2001 or who turn 45 between 1st Jan 2001 and 25th March 2010, irrespective of initial health status.
Exclusion Criteria:
- Patients with a record unlinked to deprivation due to missing or incomplete postcode of residence.
学习计划
研究是如何设计的?
设计细节
队列和干预
团体/队列 |
干预/治疗 |
---|---|
Healthy
Patients without any of the pre-specified chronic diseases
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This study is based on the retrospective analysis of linked electronic health records.
|
Multimorbid
Patients having any two or more of the pre-specified chronic diseases
|
This study is based on the retrospective analysis of linked electronic health records.
|
研究衡量的是什么?
主要结果指标
结果测量 |
措施说明 |
大体时间 |
---|---|---|
Yearly multimorbidity incidence rate
大体时间:10 years
|
Numerator: Of patients with either 0 or 1 chronic diseases as on 1st Jan of the year, all those who become multimorbid by 31st Dec of the year. Denominator: patient years at risk of patients with either 0 or 1 chronic diseases as on 1st Jan of the year |
10 years
|
Yearly multimorbidity prevalence
大体时间:10 years
|
Numerator: all those with 2 or more listed diseases on 1st July of the year.
Denominator: All eligible patients on 1st July of the year, irrespective of disease status on that date.
|
10 years
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Yearly all-cause mortality rates
大体时间:10 years
|
Numerator: number of deaths until 31st Dec of the year amongst the patients included in the denominator. Denominator: Person years at risk of patients with 0,1,2 or more diseases on 1st Jan of the year. |
10 years
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Overall life expectancy
大体时间:10 years
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Incident rates of transitions between no disease, 1 disease, 2+ diseases, and death.
|
10 years
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Health state-specific life expectancies
大体时间:10 years
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Incident rates of transitions between four health states - no disease, 1 disease, 2+ diseases, and death.
|
10 years
|
次要结果测量
结果测量 |
措施说明 |
大体时间 |
---|---|---|
Yearly non-accidental mortality rates
大体时间:10 years
|
As outcome 3 but excluding accidental deaths from the numerator
|
10 years
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合作者和调查者
调查人员
- 研究主任:Madhavi Bajekal, PhD、University College, London
研究记录日期
研究主要日期
学习开始
初级完成 (实际的)
研究完成 (预期的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (估计)
研究记录更新
最后更新发布 (估计)
上次提交的符合 QC 标准的更新
最后验证
更多信息
与本研究相关的术语
关键字
其他研究编号
- 14_179
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