Patient Outcomes After Hospitalization in Acute Geriatric Unit (DAMAGE)
Risks of Death, Hospital Readmission, and Institutionalization After Hospitalization in Acute Geriatric Unit
Three events can be considered of major importance for patients after a hospitalization in an AGU: death, hospital readmission, and institutionalization. Current published data do not allow the clinician to simultaneously estimate the risk of hospital readmission, institutionalization and death of an older patient according to his/her characteristics and various complications that occurred during the hospitalization. However, clinicians often need to estimate these risks at hospital discharge to adapt their therapeutic choices, their proposals post-hospital care, and provide reliable and fair information to the patient and his relatives.
Estimating simultaneously the hazard for each of these three events can be complex. Indeed, a death event hinder the observation of re-hospitalization or institutionalization if death occurs before these events. The death should be considered a competing risk in these analyzes. Hospital readmission may modify the risk of death or institutionalization and should be considered as an intermediate factor for these event. This complexity cannot be accounted with classical statistical models, like logistic regression models.
The purpose of this study is to use more appropriate statistical models (multi-state models) to better estimate simultaneously the risks of hospital readmission, institutionalization, and death of a patient given after hospitalization in AGU, and to show that accuracy of these estimations can be improved by taking into account complications that occurred during the stay in AGU.
研究概览
地位
条件
研究类型
注册 (实际的)
联系人和位置
学习地点
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-
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Amiens、法国
- CHU d'Amiens
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Beauvais、法国
- CH Beauvais
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Caen、法国
- CHU Caen
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Lille、法国
- Hôpital Cardiologique, CHRU
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Lomme、法国
- GHICL, Saint Philibert
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Saint quentin、法国
- CH Saint Quentin
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参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
取样方法
研究人群
描述
Inclusion Criteria:
- Age 75 years and over
- Hospitalized in Acute Geriatric Unit
- Covered by a health insurance
Exclusion Criteria:
- Refusal to participate to the study, as expressed by the patient or his/her next of kin
学习计划
研究是如何设计的?
设计细节
研究衡量的是什么?
主要结果指标
结果测量 |
大体时间 |
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Number of death after discharge
大体时间:3 months
|
3 months
|
次要结果测量
结果测量 |
措施说明 |
大体时间 |
---|---|---|
Number of death after discharge
大体时间:12 months
|
12 months
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Number of rehospitalization after discharge
大体时间:at 3 and 12 months
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at 3 and 12 months
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Number of institutionalization (NH admissions)
大体时间:at 12 months
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at 12 months
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Number of nosocomial infectious diseases during the index hospitalization
大体时间:60 days
|
60 days
|
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Duration of clostridium difficile infection
大体时间:60 days
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60 days
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Length of stay of the index hospitalization
大体时间:60 days
|
The exact duration for this outcome will correspond to the duration of the index hospitalization
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60 days
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合作者和调查者
调查人员
- 首席研究员:Jean-Baptiste Beuscart, MD, PhD、University Hospital, Lille
出版物和有用的链接
一般刊物
- Deschasse G, Charpentier A, Prod'homme C, Genin M, Delecluse C, Gaxatte C, Gerard C, Bukor Z, Devulder P, Couvreur LA, Bloch F, Puisieux F, Visade F, Beuscart JB. Transition to Comfort Care Only and End-of-Life Trajectories in an Acute Geriatric Unit: A Secondary Analysis of the DAMAGE Cohort. J Am Med Dir Assoc. 2022 Sep;23(9):1492-1498. doi: 10.1016/j.jamda.2022.04.016. Epub 2022 May 21.
- Deschasse G, Bloch F, Drumez E, Charpentier A, Visade F, Delecluse C, Loggia G, Lescure P, Attier-Zmudka J, Bloch J, Gaxatte C, Van Den Berghe W, Puisieux F, Beuscart JB. Development of a Predictive Score for Mortality at 3 and 12 Months After Discharge From an Acute Geriatric Unit as a Trigger for Advanced Care Planning. J Gerontol A Biol Sci Med Sci. 2022 Aug 12;77(8):1665-1672. doi: 10.1093/gerona/glab217.
研究记录日期
研究主要日期
学习开始 (实际的)
初级完成 (实际的)
研究完成 (实际的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (估计)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
此信息直接从 clinicaltrials.gov 网站检索,没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求,请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改,我们的网站上也会自动更新.
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