Evaluation of Biological Markers of Mesenteric Ischemia During an Ultra-trail (ISKETRAIL)
研究概览
详细说明
During physical exercise, increased sympathetic nervous system activity redistributes blood flow from splanchnic organs to working muscles. With prolonged duration and / or intensity, the splanchnic blood flow can be reduced by 80% or more. A severely reduced of splanchnic blood flow can frequently cause gastrointestinal ischemia. This ischemia associated with reduced vagal activity probably results in changes in motility and absorption.
High symptoms are reported in 40% of runners with reflux and heartburn in 15-20% of runners. The low symptoms have an incidence of about 70% in the long runs type ultra-trail.
Biological markers such as I-FABP have been shown to be useful in the diagnosis of mesenteric ischemia.
研究类型
注册 (实际的)
联系人和位置
学习地点
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Auvergne
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Clermont-Ferrand、Auvergne、法国、63003
- CHU de Clermont-Ferrand
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参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
取样方法
研究人群
描述
Inclusion Criteria:
- Healthy Voluntary Subject
- Age > 18 years
- Written consent
- Subject affiliated to Social Security
- Medical certificate (mandatory to take part in the ultra-trail)
Exclusion Criteria:
- Refusal to participate
- Subject with legal protection (guardianship, trusteeship)
学习计划
研究是如何设计的？
设计细节
队列和干预
团体/队列 |
干预/治疗 |
|---|---|
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Runners
To assess the evolution of biological markers of mesenteric ischemia during ultratrail.
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Blood test of biological markers of mesenteric ischemia
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研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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Assess biological markers of mesenteric ischemia (IFABP)
大体时间：at day 1
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during ultratrail.
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at day 1
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次要结果测量
结果测量 |
大体时间 |
|---|---|
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Relationship between digestive symptoms and biological markers (IFABP).
大体时间：at day 1
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at day 1
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合作者和调查者
调查人员
- 首席研究员：Sébastien PERBET、CHU de Clermont-Ferrand
研究记录日期
研究主要日期
学习开始 (实际的)
初级完成 (实际的)
研究完成 (实际的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (实际的)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
此信息直接从 clinicaltrials.gov 网站检索，没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求，请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改，我们的网站上也会自动更新.
Ultra-trail Participation的临床试验
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Esraa Mostafa Ahmed Abdel Aal尚未招聘局部相关（局灶性）（部分）特发性癫痫和伴有局部发作的癫痫综合征 | TRAIL：肿瘤坏死因子相关细胞凋亡诱导配体 MCP-2 | MCP-2：单核细胞趋化蛋白 2
Blood analysis的临床试验
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Hvidovre University HospitalElsassFonden终止