Upper Limit for TSH of First and Second Trimester Pregnancy in Turkey
What is the Rational Upper Limit for TSH and T4 During First and Second Trimester Pregnancy in West Black Sea Region of Turkey
Physiological changes necessitate the use of pregnancy-specific reference ranges for TSH and FT4 to diagnose thyroid dysfunction during pregnancy. Although many centers use fixed upper limits for TSH of 2.5 or 3.0 mU/L, this may lead to overdiagnosis or even overtreatment.
The new guidelines of the American Thyroid Association have considerably changed recommendations regarding thyroid function reference ranges in pregnancy accordingly. Any hospital or physician that is still using the 2.5 or 3.0 mU/l cut-off for TSH during pregnancy should evaluate their own lab-specific cut-offs.
The investigator's objective is to establish a rational reference range of serum TSH for diagnosis of subclinical hypothyroidism in the first and second trimester of pregnant women in west Black Sea region in Turkey.
研究概览
详细说明
研究类型
注册 (预期的)
联系人和位置
学习联系方式
- 姓名:Murat Yassa, MD
- 电话号码:+905335106312
- 邮箱:murat.yassa@gmail.com
学习地点
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Bartin、火鸡
- 招聘中
- Bartin State Hospital
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接触:
- Murat Yassa, MD
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参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
取样方法
研究人群
描述
Inclusion Criteria:
- Singleton pregnancy
- Free of pre-existing thyroid disease
- That do not use thyroid interfering medication
- That did not undergo IVF treatment
- TPOAb negative
Exclusion Criteria:
- Adolescent pregnancy
学习计划
研究是如何设计的?
设计细节
队列和干预
团体/队列 |
干预/治疗 |
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Pregnants
400 pregnant women with a singleton pregnancy, free of pre-existing thyroid disease, that do not use thyroid interfering medication, that did not undergo IVF treatment and are TPOAb negative.
Serum thyroid functions tests will be obtained on the first visit.
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Serum TSH, fT3, fT4 and anti-TPO
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研究衡量的是什么?
主要结果指标
结果测量 |
措施说明 |
大体时间 |
---|---|---|
TSH
大体时间:Day 1
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Serum TSH (mU/I)
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Day 1
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合作者和调查者
出版物和有用的链接
研究记录日期
研究主要日期
学习开始 (实际的)
初级完成 (预期的)
研究完成 (预期的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (实际的)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
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