Controlling Post-extraction Complications of Impacted Mandibular Third Molar
2021年7月20日 更新者：Alaa Altaweel、Al-Azhar University
Methylprednisolone and Hyaluronic Acid Versus Each Agent Alone to Control Post-extraction Complications of Impacted Mandibular Third Molar
Impacted mandibular 3rd molar will be extracted in all patients, then patients will be divided, according to material placed in extraction socket into 3 groups: control, hyaluronic acid and honey.
Then post extraction complications will be evaluated
研究概览
地位
完全的
详细说明
Impacted Mandibular third molar will be extracted under local anesthesia Through standard surgical flap elevation, after extraction and wound irrigation a material facilitate healing will be placed.
According to material will be placed patients will be divide into 3 group: control ( no material, second group hyaluronic acid, third group ( honey).. then wound will be closed.
Postoperative pain ( through visual analog scale) , edema, total dose of analgesic, mandibular movement (interincisal distance in mm) will be evaluated preoperative, 1,2,3,7, and 10 day after extraction
研究类型
介入性
注册 (实际的)
72
阶段
- 不适用
联系人和位置
本节提供了进行研究的人员的详细联系信息，以及有关进行该研究的地点的信息。
学习地点
-
-
-
Jeddah、沙特阿拉伯
- Vision college
-
-
参与标准
研究人员寻找符合特定描述的人，称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。
资格标准
适合学习的年龄
20年 至 35年 (成人)
接受健康志愿者
是的
有资格学习的性别
全部
描述
Inclusion Criteria:
- healthy patients
- patient has impacted 3rd molar
Exclusion Criteria:
- medically compromised patients Heavy smoking patients
学习计划
本节提供研究计划的详细信息，包括研究的设计方式和研究的衡量标准。
研究是如何设计的？
设计细节
- 主要用途：治疗
- 分配：随机化
- 介入模型：并行分配
- 屏蔽：无（打开标签）
武器和干预
参与者组/臂 |
干预/治疗 |
|---|---|
|
安慰剂比较：Normal saline
Normal saline irrigation after extraction and No drug placed in tooth socket
|
Normal saline irrigation and No other drug placed after extraction
|
|
有源比较器：Gengigel
Gengigel (Hyaluronic acid) placed after extraction
|
Immediately after removal of impacted tooth (hyaluronic acid) placed in extraction socket
其他名称：
|
|
有源比较器：Methylprednisolone
Methylprednisolone will be given intravenous to a patient half an hour before the surgery
|
Methylprednsolone will be injected half an hour preoperatively
|
|
有源比较器：Methylprednisolone and Gengigel
Methylprednisolone will be given intravenous to a patient half an hour before the surgery and Gengigel (Hyaluronic acid) placed after extraction
|
Methylprednisolone will be injected half an hour preoperatively and Immediately after removal of impacted tooth (hyaluronic acid) placed in extraction socket
|
研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
Interincisal distance
大体时间：Baseline (Preoperative)
|
Measuring distance between upper lower anterior teeth in mm
|
Baseline (Preoperative)
|
|
Interincisal distance
大体时间：1 day postoperative
|
Measuring distance between upper lower anterior teeth in mm
|
1 day postoperative
|
|
Interincisal distance
大体时间：2nd day postoperative
|
Measuring distance between upper lower anterior teeth in mm
|
2nd day postoperative
|
|
Interincisal distance
大体时间：3rd day postoperative
|
Measuring distance between upper lower anterior teeth in mm
|
3rd day postoperative
|
|
Interincisal distance
大体时间：7th day postoperative
|
Measuring distance between upper lower anterior teeth in mm
|
7th day postoperative
|
|
Assessment of pain using Visual analog scale
大体时间：Baseline (Preoperative)
|
Patient asked to describe pain intensity subjectively on visual analog scale where 0 mean no pain while 10 mean sever pain
|
Baseline (Preoperative)
|
|
Assessment of pain using Visual analog scale
大体时间：1st day
|
Patient asked to describe pain intensity subjectively on visual analog scale where 0 mean no pain while 10 mean sever pain
|
1st day
|
|
Assessment of pain using Visual analog scale
大体时间：2nd day
|
Patient asked to describe pain intensity subjectively on visual analog scale where 0 mean no pain while 10 mean sever pain
|
2nd day
|
|
Assessment of pain using Visual analog scale
大体时间：3rd day
|
Patient asked to describe pain intensity subjectively on visual analog scale where 0 mean no pain while 10 mean sever pain
|
3rd day
|
|
Assessment of pain using Visual analog scale
大体时间：7th day
|
Patient asked to describe pain intensity subjectively on visual analog scale where 0 mean no pain while 10 mean sever pain
|
7th day
|
|
Total amount of analgesic
大体时间：1st day postoperative
|
Total amount of analgesic Will be calculated
|
1st day postoperative
|
|
Total amount of analgesic
大体时间：2nd day postoperative
|
Total amount of analgesic Will be calculated
|
2nd day postoperative
|
|
Total amount of analgesic
大体时间：3rd day postoperative
|
Total amount of analgesic Will be calculated
|
3rd day postoperative
|
|
Total amount of analgesic
大体时间：7th day postoperative
|
Total amount of analgesic Will be calculated
|
7th day postoperative
|
|
Size of edema will be assessed from finial angle and Travis of ear to mental ala of Nes and mouth angle
大体时间：Baseline
|
Edema measured from gonial angle and Tragus to mental, angle of mouth, ala of nose, and lateral canthus of eye respectively
|
Baseline
|
|
Size of edema will be assessed from finial angle and Travis of ear to mental ala of Nes and mouth angle
大体时间：1st day postoperative
|
Edema measured from gonial angle and Tragus to mental, angle of mouth, ala of nose, and lateral canthus of eye respectively
|
1st day postoperative
|
|
Size of edema will be assessed from finial angle and Travis of ear to mental ala of Nes and mouth angle
大体时间：2nd day postoperative
|
Edema measured from gonial angle and Tragus to mental, angle of mouth, ala of nose, and lateral canthus of eye respectively
|
2nd day postoperative
|
|
Size of edema will be assessed from finial angle and Travis of ear to mental ala of Nes and mouth angle
大体时间：3rd day postoperative
|
Edema measured from gonial angle and Tragus to mental, angle of mouth, ala of nose, and lateral canthus of eye respectively
|
3rd day postoperative
|
|
Size of edema will be assessed from finial angle and Travis of ear to mental ala of Nes and mouth angle
大体时间：7th day postoperative
|
Edema measured from gonial angle and Tragus to mental, angle of mouth, ala of nose, and lateral canthus of eye respectively
|
7th day postoperative
|
合作者和调查者
在这里您可以找到参与这项研究的人员和组织。
研究记录日期
这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查，以确保它们在发布到公共网站之前符合特定的质量控制标准。
研究主要日期
学习开始 (实际的)
2021年2月10日
初级完成 (实际的)
2021年6月20日
研究完成 (实际的)
2021年6月20日
研究注册日期
首次提交
2021年3月23日
首先提交符合 QC 标准的
2021年3月24日
首次发布 (实际的)
2021年3月25日
研究记录更新
最后更新发布 (实际的)
2021年7月22日
上次提交的符合 QC 标准的更新
2021年7月20日
最后验证
2021年7月1日
更多信息
此信息直接从 clinicaltrials.gov 网站检索，没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求，请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改，我们的网站上也会自动更新.