Screening for Memory Studies
Study Overview
Status
Status
Conditions
Conditions
Intervention / Treatment
Intervention / Treatment
Detailed Description
Study Type
Study Type
Enrollment (Actual)
Enrollment
Contacts and Locations
Study Locations
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California
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Palo Alto, California, United States, 94304
- VA Palo Alto Health Care System
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-
Participation Criteria
Eligibility Criteria
Eligibility Criteria
Ages Eligible for Study
Accepts Healthy Volunteers
Sampling Method
Study Population
Description
Inclusion Criteria:
- Age 21 or over.
Exclusion Criteria:
- Major psychiatric problems.
- Major medical problems.
- Aversion to test-taking.
Study Plan
How is the study designed?
Design Details
Number of groups / cohorts
Cohorts and Interventions
Group / CohortGroup / Cohort |
Intervention / TreatmentIntervention / Treatment |
|---|---|
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Older Adults
Persons over age 60 Participants will complete the Memtrax memory screening test
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Memory Screening test
Other Names:
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What is the study measuring?
Primary Outcome Measures
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Memory Impairment
Time Frame: 90 seconds to 150 seconds (normal less than 100 seconds)
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The primary outcome measure on a 50 item Continuous Recognition Task with 25 repeated items, first display of an item is 3 seconds, new image immediately after a response (MemTrax, see: reference), is number of HITs (a memory measure).
Less than 20 suggests memory impairment and will trigger referral to a memory study.
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90 seconds to 150 seconds (normal less than 100 seconds)
|
Secondary Outcome Measures
Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Processing speed measurement with MemTrax
Time Frame: 90 - 150 seconds (normal - 95 seconds)
|
Secondary outcome measure is response time to HITs (a measure of memory processing speed), usually 0.550 to 1.5 seconds.
Slower than 1.2 seconds suggests a memory, attention, or processing speed problem, will also trigger a referral to the memory study.
Note, a third measure, number of Correct Rejections (a measure of executive function), is used to validate the first and second outcome measures.
Values below 20 suggest that the other measures might not be valid.
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90 - 150 seconds (normal - 95 seconds)
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Collaborators and Investigators
Sponsor
Sponsor
Collaborators
Collaborators
Investigators
Investigators
- Principal Investigator: J. Wesson Ashford Jr., MD, PhD, Stanford University
Publications and helpful links
General Publications
- Ashford JW, Borson S. Primary care screening for dementia and mild cognitive impairment. JAMA. 2008 Mar 12;299(10):1132-3; author reply 1133-4. doi: 10.1001/jama.299.10.1132-b. No abstract available.
- Clifford JO Jr, Anand S, Tarpin-Bernard F, Bergeron MF, Ashford CB, Bayley PJ, Ashford JW. Episodic memory assessment: effects of sex and age on performance and response time during a continuous recognition task. Front Hum Neurosci. 2024 Apr 4;18:1304221. doi: 10.3389/fnhum.2024.1304221. eCollection 2024.
Study record dates
Study Major Dates
Study Start
Study Start
Primary Completion (Actual)
Primary Completion
Study Completion (Actual)
Study Completion
Study Registration Dates
First Submitted
First Submitted
First Submitted That Met QC Criteria
First Submitted That Met QC Criteria
First Posted (Estimated)
First Posted
Study Record Updates
Last Update Posted (Actual)
Last Update Posted
Last Update Submitted That Met QC Criteria
Last Update Submitted That Met QC Criteria
Last Verified
Last Verified
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
- Neurologic Manifestations
- Brain Diseases
- Central Nervous System Diseases
- Nervous System Diseases
- Mental Disorders
- Neurobehavioral Manifestations
- Neurocognitive Disorders
- Tauopathies
- Neurodegenerative Diseases
- Pathological Conditions, Signs and Symptoms
- Signs and Symptoms
- Alzheimer Disease
- Dementia
- Memory Disorders
Other Study ID Numbers
Other Study ID Numbers
- SU-06302009-2900
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
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