A Follow-up Colonoscopy Examination in Patients Who Had Previously Undergone Screening Colonoscopy

May 9, 2008 updated by: Chinese University of Hong Kong
  • To determine the prevalence of colonic neoplasm in patients who had previously undergone screening colonoscopy
  • To determine the optimal time interval for re-screening in average risk individuals
  • To determine potential baseline characteristics that predicts adenoma recurrence

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

Colorectal cancer (CRC) is the second commonest cancer in Hong Kong, and tends to be increasing. Screening for colorectal cancer can reduce the cancer incidence and mortality by detecting early lesions. However, the best interval for a follow up colonoscopy, particularly for those with normal baseline colonoscopy, remains largely unknown.

This study aim to determine the prevalence of colonic neoplasm in average-risk patients who had previously undergone screening colonoscopy and the optimal time interval for re-screening.

Study Type

Observational

Enrollment (Actual)

560

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • China
      • Hong Kong (SAR), China
        • Endoscopy Center, Prince of Wales Hospital

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

50 years to 75 years (Adult, Older Adult)

Accepts Healthy Volunteers

Yes

Genders Eligible for Study

All

Sampling Method

Non-Probability Sample

Study Population

Subjects who are previously participated in one of our two screening colonoscopy studies [Sung, Gastroenterol 2003; Leung, AJG 2004]

Description

Inclusion Criteria:

  • Subjects who are previously participated in one of our two screening colonoscopy studies [Sung, Gastroenterol 2003; Leung, AJG 2004]
  • Asymptomatic on first screening colonoscopy
  • Age>50and <75
  • No family history of CRC
  • No other colonoscopy except the baseline screening colonoscopy

Exclusion Criteria:

  • Subjects who refused consent
  • Subjects who are not warrant follow up colonoscopy

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
A
colonic adenoma
Procedure: colonoscopy
proform a follow up colonoscopy in the 5 year period from index colonoscopy
Other Names:
  • follow up colonoscopy
B
colonic without adenoma
Procedure: colonoscopy
proform a follow up colonoscopy in the 5 year period from index colonoscopy
Other Names:
  • follow up colonoscopy

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
The prevalence of advanced colonic adenoma in the re-screening population
Time Frame: 5 year from index colonoscopy
5 year from index colonoscopy

Secondary Outcome Measures

Outcome Measure
Time Frame
The time to adenoma adenoma development according to different baseline characteristics of patients and colonoscopy findings
Time Frame: 5 years from index colonoscopy
5 years from index colonoscopy

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Chinese University of Hong Kong

Investigators

  • Principal Investigator: Wai K Leung, MD, CUHK

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

March 1, 2006

Primary Completion (Actual)

November 1, 2007

Study Completion (Actual)

November 1, 2007

Study Registration Dates

First Submitted

January 20, 2006

First Submitted That Met QC Criteria

January 20, 2006

First Posted (Estimate)

January 23, 2006

Study Record Updates

Last Update Posted (Estimate)

May 12, 2008

Last Update Submitted That Met QC Criteria

May 9, 2008

Last Verified

May 1, 2008

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • FUC

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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