Efficacy of Oral Colchicine in Prevention of Proliferative Vitreoretinopathy in Rhegmatogenous Retinal Detachment

Sponsors

Lead Sponsor: Shahid Beheshti University of Medical Sciences

Source Shahid Beheshti University of Medical Sciences
Brief Summary

This clinical trial will test the efficacy and safety of oral colchicine in prevention of proliferative vitreoretinopathy (PVR) in cases of rhegmatogenous retinal detachment

Overall Status Unknown status
Start Date March 2004
Completion Date August 2006
Phase Phase 3
Study Type Interventional
Primary Outcome
Measure Time Frame
proliferative vitreoretinopathy
retinal reattachment rate
Secondary Outcome
Measure Time Frame
visual acuity
reoperation
macular pucker
Condition
Intervention

Intervention Type: Drug

Intervention Name: colchicine

Eligibility

Criteria:

Inclusion Criteria:

- Rhegmatogenous retinal detachment

Exclusion Criteria:

- PVR grade C

- Duration of retinal detachment ≥ one month

- History of cataract surgery

- History of RD surgery

Gender: All

Minimum Age: 18 Years

Maximum Age: 65 Years

Healthy Volunteers: No

Overall Official
Last Name Role Affiliation
Hamid Ahmadieh, MD Principal Investigator Ophthalmic Research Center of Shaheed Beheshti Medical University
Location
Facility: Hamid Ahmadieh,MD
Location Countries

Iran, Islamic Republic of

Verification Date

March 2004

Keywords
Has Expanded Access No
Condition Browse
Study Design Info

Allocation: Randomized

Intervention Model: Parallel Assignment

Primary Purpose: Treatment

Masking: Double

Source: ClinicalTrials.gov