Can Blood Glucose Levels During the Perioperative Period Identify a Population at Risk for Hyperglycemia?

Can Blood Glucose Levels During the Perioperative Period Identify a Population at Risk for Hyperglycemia

Surgery performed during general anesthesia induces a stress effect on the body. Our plan is to identify population at risk of hyperglycemia during perioperative period.

Study Overview

• Status: Completed
• Conditions: Hyperglycemia; General Anesthesia

Detailed Description

This is a prospective study to define the relationship between time profile of glucose control before, during and after surgery with patient variables, surgical variables and anesthetic variables. Serum glucose levels will be measured preoperatively and then at 30 minute intervals during surgery. Pain score, pain medication and glucose levels will be measured in the post anesthesia recovery room. Subjects will be contacted 2 weeks following the date of surgery to determine the incidence of postoperative complications.

• Study Type: Observational
• Enrollment (Actual): 308

Contacts and Locations

Study Locations

• United States
  • New Jersey
    • Newark, New Jersey, United States, 07101
      • University of Medicine & Dentistry of New Jersey

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 80 years (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

non-diabetic adults undergoing surgery

Description

Inclusion Criteria:

• Elective surgery
• 18-80 years of age

Exclusion Criteria:

• Known diabetics
• Pregnant patients
• Cardiac surgery patients
• Liver transplant patients

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Time Frame
glucose level at specific points	Intraoperatively and in the PACU

Secondary Outcome Measures

Outcome Measure	Time Frame
pt telephoned to assess for complications	within 2 weeks of surgery

Collaborators and Investigators

• Sponsor: University of Medicine and Dentistry of New Jersey
• Investigators: Principal Investigator: Vasanti Tilak, MD, University of Medicine & Dentistry of New Jersey-NJMS

Study record dates

Study Major Dates

• Study Start: September 1, 2006
• Primary Completion (Actual): June 1, 2010
• Study Completion (Actual): June 1, 2010

Study Registration Dates

• First Submitted: April 30, 2007
• First Submitted That Met QC Criteria: May 1, 2007
• First Posted (Estimate): May 2, 2007

Study Record Updates

• Last Update Posted (Estimate): January 25, 2013
• Last Update Submitted That Met QC Criteria: January 24, 2013
• Last Verified: January 1, 2013

More Information

Terms related to this study

• Keywords: non diabetic; catabolic energy state
• Additional Relevant MeSH Terms: Glucose Metabolism Disorders; Metabolic Diseases; Hyperglycemia
• Other Study ID Numbers: 0120060208