Excimer Lamp Versus Excimer Laser in Vitiligo Treatment
June 15, 2026 updated by: Centre Hospitalier Universitaire de Nice
Comparative Study of 308nm Excimer Lamp and 308nm Excimer Laser in the Treatment of Vitiligo
308 nm excimer lamp and 308 nm excimer laser have both provide interesting results in treating vitiligo. They have the same wavelength but the type of emission of the photons is different. To date there is no direct comparative data concerning these two devices in this indication.
The aim of the study is to make an intra-individual prospective comparison between these two phototherapies.
Study Overview
Status
Completed
Conditions
Intervention / Treatment
Study Type
Interventional
Phase
- Phase 3
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
-
-
Nice, France
- Department of Dermatology, University Hospital of Nice
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-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
18 years and older (Adult, Older Adult)
Accepts Healthy Volunteers
No
Description
Inclusion Criteria:
- patient above 18
- vitiligo for more than 3 months
- at least 2 vitiligo symmetric patches more than 10cm²
- to read and understand the inform consent
- to have a social security number
- non pregnant for women
Exclusion Criteria:
- pregnant women
- keloids
- history of radiotherapy or skin cancer in the treated areas
- treatment for vitiligo in the past 4 weeks
- phototherapy in the past 12 weeks; history of photodermatosis
- treatment inducing photosensibilization
- immunosuppression
- patient who participated in a study in the past 3 months
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
|---|---|
|
Active Comparator: A
308 nm excimer lamp
|
50 mJ/cm² below the MED (minimal erythemal dose) and progressive increase Twice a week for 12 weeks
|
|
Active Comparator: B
308 nm excimer laser
|
50 mJ/cm² below the MED (minimal erythemal dose) and progressive increase Twice a week for 12 weeks (same doses will be used between the 2 arms)
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Time Frame |
|---|---|
|
Repigmentation rate in the treated areas
Time Frame: 12 weeks
|
12 weeks
|
Secondary Outcome Measures
Outcome Measure |
Time Frame |
|---|---|
|
Tolerance and safety of the treatments
Time Frame: 12 weeks
|
12 weeks
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Actual)
March 17, 2009
Primary Completion (Actual)
November 25, 2009
Study Completion (Actual)
June 15, 2010
Study Registration Dates
First Submitted
June 10, 2008
First Submitted That Met QC Criteria
June 11, 2008
First Posted (Estimated)
June 12, 2008
Study Record Updates
Last Update Posted (Actual)
June 16, 2026
Last Update Submitted That Met QC Criteria
June 15, 2026
Last Verified
June 1, 2026
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
Other Study ID Numbers
- NICE-VIT1
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.