Strength Training for Chronic Stroke Patients

June 22, 2012 updated by: Norwegian University of Science and Technology

Maximal Strength Training for Chronic Phase Stroke Patients

The study aims to investigate the effects of strength training on maximal strength, walking ability and neural function in chronic stroke patients. The strength training intervention in this study is different to all previous interventions for stroke patients.

Maximal Strength Training (MST) involves weights of up to 90% of the participants 1 repetition maximum and has a focus on the explosive development of force. This study will use these principles for unilateral leg press and plantarflexion exercises. Only 2 previous studies have investigated high intensity strength training for stroke patients and they used intensities of 80% 1RM. Previous MST interventions have shown large increases in strength, rate of force development and this has transferred to improved walking economy.

The investigators predict that MST will give large increases in strength, improved rate of force development (RFD) and walking economy. The investigators expect that better neural function will account for the improvements. This study could provide evidence for the adoption of a completely different method of strength rehabilitation for stroke survivors.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Actual)

10

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Norway
      • Trondheim, Norway, 7050
        • Avdeling for ervervede hjerneskader, Klinikk for fysikalsk medisin og rehabilitering, St Olavs Hospital

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years to 67 years (Adult, Older Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Description

Inclusion Criteria:

  • Under 67 years old
  • Suffered from a stroke at least 6 months previously
  • Living in the Trondheim area such that travel costs can be covered by 1500 NOK
  • Must be able to walk, although use of aids is permitted

Exclusion Criteria:

  • Participants must not have cognitive, visuospatial or comprehension deficits to magnitude such that it interferes with the ability to perform testing and training
  • Participants must be medically unstable (e.g. uncontrollably high blood pressure (140/90), arrythmia, other heart instabilities or other known comorbid diseases)
  • Participants must not be known to be pregnant

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: N/A
  • Interventional Model: Single Group Assignment
  • Masking: None (Open Label)

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
Unilateral 1 repetition maximum for leg press and plantarflexion
Time Frame: November 2009-March 2010
November 2009-March 2010

Secondary Outcome Measures

Outcome Measure
Time Frame
Rate of force development in unilateral leg press and plantarflexion
Time Frame: November 2009 - March 2010
November 2009 - March 2010
Maximal oxygen uptake and walking economy
Time Frame: November 2009 - March 2010
November 2009 - March 2010
Timed Up and Go Test
Time Frame: November 2009 - March 2010
November 2009 - March 2010
4 Step Balance Test
Time Frame: November 2009 - March 2010
November 2009 - March 2010
V-Wave (using sEMG equipment) of soleus during static plantarflexion
Time Frame: November 2009 - March 2010
November 2009 - March 2010
Blood lipid profile
Time Frame: November 2009 - March 2010
November 2009 - March 2010
6 Minute Walk Test
Time Frame: November 2009 - March 2010
November 2009 - March 2010
Jump Height of a countermovement jump
Time Frame: November 2009 - March 2010
November 2009 - March 2010
SF-36 Quality of life questionnaire, Norwegian version
Time Frame: November 2009 - March 2010
November 2009 - March 2010

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Norwegian University of Science and Technology

Investigators

  • Principal Investigator: Tom Tørhaug, MD, St.Olav's University hospital
  • Study Chair: Jan Hoff, PhD, National Taiwan Normal University
  • Principal Investigator: Jan Helgerud, National Taiwan Normal University
  • Principal Investigator: Tor Ivar Gjellesvik, National Taiwan Normal University
  • Principal Investigator: Marius Fimland, National Taiwan Normal University
  • Principal Investigator: Per Marius R Moen, National Taiwan Normal University
  • Principal Investigator: Tessa Hill, National Taiwan Normal University

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

November 1, 2009

Primary Completion (Actual)

March 1, 2010

Study Completion (Actual)

March 1, 2010

Study Registration Dates

First Submitted

October 27, 2009

First Submitted That Met QC Criteria

October 27, 2009

First Posted (Estimate)

October 28, 2009

Study Record Updates

Last Update Posted (Estimate)

June 25, 2012

Last Update Submitted That Met QC Criteria

June 22, 2012

Last Verified

June 1, 2012

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 2009/1241

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

Clinical Trials on Stroke

Clinical Trials on Maximal strength training

Search Similar Trials

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Taiwan

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations

Subscribe