The Effects of Cinnamon on Postprandial Blood Glucose, and Insulin in Subjects With Impaired Glucose Tolerance

Effects of Cinnamon on Postprandial Blood Glucose, and Insulin in Subjects With Type 2 Diabetes or Impaired Glucose Tolerance

To study the effect of cinnamon on postprandial blood glucose, and plasma concentrations of insulin in subjects with impaired glucose tolerance.

Study Overview

• Status: Completed
• Conditions: Diabetes

Detailed Description

Ten subjects with impaired glucose tolerance were assessed in a crossover trial. A standard 75 g oral glucose tolerance test (OGTT) was served with placebo or cinnamon capsules. Finger-prick capillary and venous blood samples were taken before and 15, 30, 45, 60, 90, 120, 150, and 180 min after the start of the OGTT to measure glucose, and insulin.

• Study Type: Observational
• Enrollment (Actual): 10

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 80 years (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Probability Sample

Study Population

All subjects were recruited from the population in southern Sweden.

Description

Inclusion Criteria:

• Patients were selected for the study on the basis of the following inclusion criteria: diagnosis of impaired glucose tolerance for < 12 months before enrollment. Glucose tolerance status and fasting blood glucose levels were evaluated using the criteria established by the American Diabetes Association.

Exclusion Criteria:

• Subjects who had thyroid disorders, or used insulin, oral hypoglycemics, and insulin-sensitizing drugs within 60 days before enrollment were excluded.

Study Plan

How is the study designed?

Collaborators and Investigators

• Sponsor: Skane University Hospital
• Collaborators: Lund University
• Investigators: Principal Investigator: Joanna Hlebowicz, MD, PhD, Skane University Hospital

Study record dates

Study Major Dates

• Study Start: May 1, 2009
• Study Completion (Actual): September 1, 2009

Study Registration Dates

• First Submitted: December 7, 2009
• First Submitted That Met QC Criteria: December 7, 2009
• First Posted (Estimate): December 8, 2009

Study Record Updates

• Last Update Posted (Estimate): December 8, 2009
• Last Update Submitted That Met QC Criteria: December 7, 2009
• Last Verified: May 1, 2009

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Glucose Metabolism Disorders; Metabolic Diseases; Hyperglycemia; Glucose Intolerance
• Other Study ID Numbers: 353/2008a