Further Validation of the Memory Orientation Screening Test (MOST):A 5-minute Screening Test for Dementia in Primary Care Practice

Further Validation of the Memory Orientation Screening Test (MOST): A 5-minute Screening Test for Dementia in Primary Care Practice

The purpose of this study is to apply a recently developed screening test for dementia, the Memory Orientation Screening Test (MOST) to two additional groups. Group one is composed of 150 elders who do not have dementia and are residing in the community so that we can determine what is a "normal" MOST score. These subjects will also be individually administered a one-hour battery composed of other commonly used tests of memory and information processing. Group two is composed of 150 elders who are administered the MOST by a nurse as part of their regular visit to the primary care doctor's office, and their scores will be compared against a rating of their cognitive ability made independently by the doctor or another nurse. Their scores will also be compared with a list of their medical problems and medications. Our hypothesis for the first group is that the MOST scores will be higher in the normal group than in the previous clinical groups and that MOST scores will correlate significantly with other neurocognitive tests. Our hypothesis for the second group is that the MOST can be administered quickly and easily by briefly trained nurses, that it will compare highly with doctor opinions, and that patients with known medical conditions related to dementia, such as hypertension or diabetes, will have lower MOST scores than patients in better health.

Study Overview

• Status: Unknown
• Conditions: Dementia

• Study Type: Observational
• Enrollment (Anticipated): 300

Contacts and Locations

Study Locations

• United States
  • Massachusetts
    • Springfield, Massachusetts, United States, 01105
      • Recruiting
      • Clionsky Neuro Systems, LLC
      • Contact: Mitchell I Clionsky, Ph.D.; Phone Number: 413-734-1799; Email: clionsky@braindoc.com
      • Contact: Emilymarie Clionsky, M.D.; Phone Number: 413-734-1799; Email: emily4cns@comcast.net
      • Principal Investigator: Mitchell I Clionsky, Ph.D.

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 65 years and older (Older Adult)
• Accepts Healthy Volunteers: Yes
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

Community sample and primary care clinic

Description

Inclusion Criteria:

• Age 65 or older

Exclusion Criteria:

• Younger than 65,
• diagnosed with dementia,
• blind,
• non-English speaking

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort
Normal community dwelling elders; Individuals age 65 and older who live in the community

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Time Frame
Memory Orientation Screening Test score	Day 1

Secondary Outcome Measures

Outcome Measure	Time Frame
Other neuropsychological test scores and doctor ratings	Day 1

Collaborators and Investigators

• Sponsor: Clionsky, Mitchell, Ph.D., ABPP(CN)
• Investigators: Principal Investigator: Mitchell I Clionsky, Ph.D., Clionsky Neuro Systems

Study record dates

Study Major Dates

• Study Start: May 1, 2008
• Primary Completion (Anticipated): May 1, 2010
• Study Completion (Anticipated): September 1, 2010

Study Registration Dates

• First Submitted: January 23, 2010
• First Submitted That Met QC Criteria: January 26, 2010
• First Posted (Estimate): January 27, 2010

Study Record Updates

• Last Update Posted (Estimate): February 9, 2010
• Last Update Submitted That Met QC Criteria: February 7, 2010
• Last Verified: January 1, 2010

More Information

Terms related to this study

• Keywords: Dementia; Memory; Cognition; Screening Tests; MOST
• Additional Relevant MeSH Terms: Mental Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Neurocognitive Disorders; Dementia
• Other Study ID Numbers: SP2008-004