- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT01069250
Dynamic and Static Autoregulation After Brain Injury
August 21, 2013 updated by: Patrick Schramm, Johannes Gutenberg University Mainz
Serial Measurement of Static and Dynamic Cerebrovascular Autoregulation After Brain Injury
The aim of the study assesses static and dynamic cerebrovascular autoregulation daily over one week in patients with traumatic brain injury or intracranial hemorrhage to quantify the temporal profile of the autoregulatory status.
Study Overview
Status
Completed
Intervention / Treatment
Study Type
Observational
Enrollment (Actual)
16
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
-
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Mainz, Germany, 55131
- University Medical Center of the Johannes Gutenberg-University Mainz
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Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
18 years and older (Adult, Older Adult)
Accepts Healthy Volunteers
No
Genders Eligible for Study
All
Sampling Method
Non-Probability Sample
Study Population
Patients after traumatic brain injury or intracranial bleeding wich had a Glasgow-Coma-Scale (GCS) of less than 8 and were initially sedated, intubated and mechanically ventilated.
Description
Inclusion Criteria:
- Traumatic brain injury
- Intracranial hemorrhage
Exclusion Criteria:
- Measurement of TCD were impossible
- Injury of the legs (if the both tigh cuffs for dynamic autoregulation could not be fixed)
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
Cohorts and Interventions
Group / Cohort |
Intervention / Treatment |
---|---|
Brain injury
Patients after traumatic brain injury or spontaneous intracranial bleeding
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What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
Disturbed cerebrovascular autoregulation after brain injury
Time Frame: 7 days
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7 days
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Publications and helpful links
The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start
August 1, 2001
Primary Completion (Actual)
December 1, 2009
Study Completion (Actual)
February 1, 2010
Study Registration Dates
First Submitted
February 16, 2010
First Submitted That Met QC Criteria
February 16, 2010
First Posted (Estimate)
February 17, 2010
Study Record Updates
Last Update Posted (Estimate)
August 22, 2013
Last Update Submitted That Met QC Criteria
August 21, 2013
Last Verified
August 1, 2013
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
- Pathologic Processes
- Cardiovascular Diseases
- Vascular Diseases
- Cerebrovascular Disorders
- Brain Diseases
- Central Nervous System Diseases
- Nervous System Diseases
- Craniocerebral Trauma
- Trauma, Nervous System
- Brain Injuries
- Wounds and Injuries
- Hemorrhage
- Brain Injuries, Traumatic
- Intracranial Hemorrhages
Other Study ID Numbers
- 2001 448/01
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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