- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT01490463
Brain Lesions Following Endovascular and Surgical Treatment of Unruptured Intracranial Aneurysms (LESUIA)
January 28, 2013 updated by: Erdem Güresir, Johann Wolfgang Goethe University Hospital
Brain Lesions Following Endovascular and Surgical Treatment of Unruptured Intracranial Aneurysms: Incidence and Influence on Clinical Outcome in a Prospective Study.
The purpose of this study is to determine the incidence and impact of brain lesions in MRI after coiling and clipping of unruptured intracranial aneurysms on clinical and neurological outcome of patients.
Study Overview
Status
Completed
Conditions
Detailed Description
Silent ischemic lesions after treatment of unruptured intracranial aneurysm (UIA) might alter patients' clinical and neurological outcome.
Furthermore silent brain lesions are not well documented after endovascular and surgical treatment of unruptured intracranial aneurysms.
Therefore, the investigators investigate the incidence and influence of treatment-related ischemic lesions in magnetic resonance / diffusion-weighted-imaging after endovascular and surgical treatment of UIA.
Study Type
Observational
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
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Hessen
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Frankfurt am Main, Hessen, Germany
- Department of Neurosurgery, Goethe-University
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Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
18 years to 80 years (Adult, Older Adult)
Accepts Healthy Volunteers
No
Genders Eligible for Study
All
Sampling Method
Non-Probability Sample
Study Population
Patients with unruptured intracranial aneurysm undergoing endovascular or surgical treatment
Description
Inclusion Criteria:
- diagnosis and treatment of unruptured intracranial aneurysm
- age ≥ 18 yrs
- written informed consent by patients prior to study participation
- willingness to participate in follow-up
Exclusion Criteria:
- ruptured intracranial aneurysm
- contraindication for MRI
- Participation in an intervention-/AMG-study
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Observational Models: Cohort
- Time Perspectives: Prospective
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Publications and helpful links
The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start
August 1, 2011
Primary Completion (Actual)
January 1, 2013
Study Completion (Actual)
January 1, 2013
Study Registration Dates
First Submitted
December 12, 2011
First Submitted That Met QC Criteria
December 12, 2011
First Posted (Estimate)
December 13, 2011
Study Record Updates
Last Update Posted (Estimate)
January 30, 2013
Last Update Submitted That Met QC Criteria
January 28, 2013
Last Verified
January 1, 2013
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
Other Study ID Numbers
- JohannWGUH_LESUIA
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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