Correlation Between Glycated Hemoglobin and Mean Plasma Glucose in Hemodialysis Patients

Correlation Between Glycated Hemoglobin and Mean Plasma Glucose in Hemodialysis Patients.

The investigators are studying the correlation between Hba1c and the mean plasma glucose in diabetic hemodialysis patients.We are reviewing if HbA1c is a good clinical tool to assess glycemic control over a 3 months duration in hemodialysis patients

Study Overview

• Status: Completed
• Conditions: ESRD

Detailed Description

The Hb turnover in hemodialysis population is higher than the general population leading to a general believe that HbA1c tend to underestimate mean plasma glucose.

The investigators are trying to define the correlation between mean plasma glucose and HbA1c in the hemodialysis population and trying to study the factors that could affect this correlation (dose of erythropoetin, ret count..) We are trying to see if HbA1c is a better tool to assess glycemic control over 1 month than glycemic control over 3 month.

This clinicaly will translate in obtaining HbA1c more frequently in hemodialysis patients to assess their glycemic control.

• Study Type: Observational
• Enrollment (Actual): 159

Contacts and Locations

Study Locations

• United States
  • New York
    • Staten Island, New York, United States, 10305
      • Staten Island University Hospital

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

all hemodialysis and diabetic population

Description

Inclusion Criteria:

• Age>18
• Hemodialysis and diabetic
• Lab data are available for more than 6 months

Exclusion Criteria:

• Lab data not available

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort
diabetic hemodialysis; all patient diabetic and on hemodialysis were involved if they are on hemodialysis for more than 3 months

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Time Frame
Measure levels of plasma blood glucose and HbA1c	6 month intervals

Secondary Outcome Measures

Outcome Measure	Time Frame
Measure ferritin, erythropoetin dose, reticulocytes count	6 month intervals

Collaborators and Investigators

• Sponsor: Northwell Health
• Investigators: Principal Investigator: suzanne el-sayegh, md, statenisland university hospital

Study record dates

Study Major Dates

• Study Start: March 1, 2009
• Primary Completion (Actual): May 1, 2009
• Study Completion (Actual): May 1, 2009

Study Registration Dates

• First Submitted: June 3, 2010
• First Submitted That Met QC Criteria: July 2, 2012
• First Posted (Estimate): July 6, 2012

Study Record Updates

• Last Update Posted (Estimate): July 6, 2012
• Last Update Submitted That Met QC Criteria: July 2, 2012
• Last Verified: July 1, 2012

More Information

Terms related to this study

• Keywords: glycated hemoglobin; mean plasma glucose
• Other Study ID Numbers: 09-001 (SIUH IRB)