Expanding Antimicrobial Stewardship

Gold standard diagnostic criteria for diagnosing acute infection in older adult patients in the Emergency Department do not currently exist. These patients often have atypical presentations which can complicate diagnosis and treatment. The development of an antimicrobial stewardship program for Emergency Department older adult patients can ultimately improve the accuracy of diagnosis and correct antimicrobial prescribing. This research study involves data collection from enrolled subjects and treating physicians. The data will be collected using a patient interview which will be answered directly by the patient or caregiver. Additional surveys will be administered to the Emergency Department treating physician and subsequent physician. Additional data will be abstracted from the Emergency Department chart and from additional charts that often accompanies the patient to the Emergency Department. A physician adjudication process will occur if there is disagreement in diagnosis between the treating Emergency Department physician and succeeding physician.

Study Overview

• Status: Completed
• Conditions: Infection

• Study Type: Observational
• Enrollment (Actual): 437

Contacts and Locations

Study Locations

• United States
  • Ohio
    • Columbus, Ohio, United States, 43210
      • Wexner Medical Center at the Ohio State University

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 65 years and older (Older Adult)
• Accepts Healthy Volunteers: Yes
• Genders Eligible for Study: All

• Sampling Method: Probability Sample

Study Population

Adults 65 years of age and older who present to the Emergency Department.

Description

Inclusion Criteria:

• 65 years of age

Exclusion Criteria:

• Patient incarcerated
• Chief complaint of suicidal or homicidal ideation
• Patient primarily evaluated by the trauma team

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort
Older Adults; Adults 65 years and older who present to the Emergency Department.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Time Frame
Presence of infection while in the Emergency Department	participants will be followed for the duration of hospital stay, an expected average of 4 days.

Collaborators and Investigators

• Sponsor: Jeffrey Caterino
• Investigators: Principal Investigator: Jeffrey M Caterino, MD, MPH, Ohio State University

Study record dates

Study Major Dates

• Study Start: August 1, 2011
• Primary Completion (Actual): August 1, 2013
• Study Completion (Actual): August 1, 2013

Study Registration Dates

• First Submitted: October 23, 2012
• First Submitted That Met QC Criteria: December 7, 2012
• First Posted (Estimate): December 11, 2012

Study Record Updates

• Last Update Posted (Estimate): November 8, 2013
• Last Update Submitted That Met QC Criteria: November 6, 2013
• Last Verified: November 1, 2013

More Information

Terms related to this study

• Other Study ID Numbers: 2011H0165