Supragingival Plaque Removal With and Without Dentifrice

Supragingival Plaque Removal With and Without Dentifrice: A Randomized Controlled Trial

Purpose: The aim of this study was to compare the efficacy of dental biofilm removal by brushing with and without conventional toothpaste. Settings and Design: Twenty-four students aged 17 to 28 years old participated in this randomized clinical trial.

Materials and Methods: Quadrants 1-3 or 2-4 were randomly allocated to the test group (brushing without dentifrice) or control group (brushing with dentifrice). After 72 hours of cessation of oral hygiene, Quigley & Hein (Turesky) plaque index was assessed before and after brushing by a calibrated and blind examiner. Overtime and intergroup comparisons were performed by paired sample t test.

Study Overview

• Status: Completed
• Conditions: Dental Plaque
• Intervention / Treatment: Other: Toothbrushing With Dentifrice; Other: Toothbrushing Without Dentifrice

• Study Type: Interventional
• Enrollment (Actual): 24
• Phase: Phase 2

Contacts and Locations

Study Locations

• Brazil
  • Rio Grande do Sul
    • Santa Maria, Rio Grande do Sul, Brazil, 97010-491
      • School of Dentistry, Franciscan University Center

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 17 years to 28 years (Child, Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

Description

Inclusion Criteria:

• students of both genders systemically healthy.

Exclusion Criteria:

• individuals who exhibited gingivitis (presence of gingival bleeding at any site);
• probing depth > 3mm and/or attachment loss >3mm at any site;
• using orthodontic appliance devices, dental prostheses, dental implants;
• presence of abrasions, restorations and/or carious lesions at cervical region;
• individuals who had less than 20 natural teeth.

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Prevention
• Allocation: Randomized
• Interventional Model: Crossover Assignment
• Masking: Quadruple

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Active Comparator: Toothbrushing With Dentifrice; After 72 hours of absence oral hygiene, patients performed toothbrushing with common dentifrice.	Other: Toothbrushing With Dentifrice; The participants were instructed to interrupt any chemical and/or mechanical oral hygiene procedure for 72 hours. Dental plaque was stained by a 2% erithrosin solution, followed by a mouth rinsing with water for 1 minute. Next, the set of dental quadrants (1-3 and 2-4) were randomly allocated to experimental groups by the flip of a coin. One of the sets was brushed with multi bristle brush without the use of dentifrice and the second set was brushed with multi bristle brush using dentifrice. Toothbrushing was performed by the individual's regular technique timed. Two minutes was used for each set. After toothbrushing, the dental biofilm was again stained and evaluated by the same examiner, who was blind to the quadrants brushed with or without dentifrice.; Other Names: Brushed with multi bristle brush; Dentifrice closeUp
Experimental: Toothbrushing Without Dentifrice; After 72 hours of absence oral hygiene, patients performed toothbrushing without dentifrice.	Other: Toothbrushing Without Dentifrice; The participants were instructed to interrupt any chemical and/or mechanical oral hygiene procedure for 72 hours. Then, dental plaque was stained by a 2% erithrosin solution, followed by a mouth rinsing with water for 1 minute. Next, the set of dental quadrants (1-3 and 2-4) were randomly allocated to experimental groups by the flip of a coin. One of the sets was brushed with multi bristle brush without the use of dentifrice and the second set was brushed with multi bristle brush using dentifrice. Toothbrushing was performed by the individual's regular technique timed. Two minutes was used for each set. After toothbrushing, the dental biofilm was again stained and evaluated by the same examiner, who was blind to the quadrants brushed with or without dentifrice.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Dental plaque	The presence of plaque was determined by Quigley and Hein (QH) (19) modified by Turesky index.	Three days

Collaborators and Investigators

• Sponsor: Franciscan University Center

Study record dates

Study Major Dates

• Study Start: July 1, 2009
• Primary Completion (Actual): September 1, 2010
• Study Completion (Actual): November 1, 2010

Study Registration Dates

• First Submitted: March 9, 2013
• First Submitted That Met QC Criteria: November 12, 2013
• First Posted (Estimate): November 19, 2013

Study Record Updates

• Last Update Posted (Estimate): November 19, 2013
• Last Update Submitted That Met QC Criteria: November 12, 2013
• Last Verified: November 1, 2013

More Information

Terms related to this study

• Keywords: Oral hygiene; Dentifrice; Dental plaque; Toothbrushing
• Additional Relevant MeSH Terms: Stomatognathic Diseases; Tooth Diseases; Dental Deposits; Dental Plaque
• Other Study ID Numbers: RAntoniazzi