Validation of the French Translation of the Scale HSCL25 in the Diagnosis of Depression in Primary Care (HSCL25)

Depression has emotional consequences, social and important business. Reaching at least 7.5% of French aged 15 to 85 years. General Practitioners are the first professional consulted in terms of frequency of consultations. Indeed, in primary care, 10 to 25% of patients with depression that General Practitioners are often alone to support and follow. But General Practitioners are faced with diagnostic difficulties facing the diagnosis of depression, because if the patient does not engage itself, no tool is validated in France to help them in their diagnosis. However, standardized questionary exist that allow to overcome this difficulty. Questionary used in other european countries. Among them, the HSCL25 scale was selected by a systematic review of literature and a RAND UCLA type of consensus procedure. This HSCL25 scale is the most efficient for the diagnosis of depression in terms of efficiency tool, reproducibility and ergonomics. However, it remains necessary to confirm its validity in terms of the French translation and in terms of efficiency.

Study Overview

• Status: Completed
• Conditions: Depression
• Intervention / Treatment: Other: HSCL25 scale; Other: PSE9 questionary

• Study Type: Interventional
• Enrollment (Actual): 1128
• Phase: Not Applicable

Contacts and Locations

Study Locations

• France
  • France
    • Brest, France, France, 29200
      • Cabinet médical en zone urbaine
    • Lanmeur, France, France, 29620
      • Cabinet médical en zone rurale - Pôle Santé Universitaire
    • Plounéour-Trez, France, France, 29890
      • Cabinet médical en zone semi-rurale

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: No

Description

Inclusion Criteria:

• Adult (18 and over) consultant in primary care

Exclusion Criteria:

• Child or young person under 18
• Women with a declared pregnancy to prevent puerperal depression whose support is different.
• Adult consultant to obtain a medical certificate
• Psychotic patients and\or requiring immediate care

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Other
• Allocation: Randomized
• Interventional Model: Single Group Assignment
• Masking: None (Open Label)

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Other: No depressed; If the result of the HSCL25 scale is inferior than 1.75, then the patient is considered as no depressed. 50 of these patients have to have a psychological interview with the PSE9 questionary to validate the result of the HSCL25 scale.	Other: HSCL25 scale; The patient must answer to 25 questions of the HSCL25 scale. In function of the results, the patients was diagnosed depressed (≥1.75) or not depressed (<1.75); Other: PSE9 questionary; On the 900 patients recruited, 50 patients who was diagnosed depressed or no depressed have to have a psychological interview with the PSE9 questionary to validate the first diagnosis done by the HSCL25 scale
Other: Depressed; If the result of the HSCL25 scale is superior or equal to 1.75, then the patient is considered as depressed. 50 of these patients have to have a psychological interview with the PSE9 questionary to validate the result of the HSCL25 scale.	Other: HSCL25 scale; The patient must answer to 25 questions of the HSCL25 scale. In function of the results, the patients was diagnosed depressed (≥1.75) or not depressed (<1.75); Other: PSE9 questionary; On the 900 patients recruited, 50 patients who was diagnosed depressed or no depressed have to have a psychological interview with the PSE9 questionary to validate the first diagnosis done by the HSCL25 scale

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
To validate the French translation of the HSCL25 scale	The score between HSCL25 scale and PSE9 questionary will be compared	1 month
To assess the HSCL25 scale diagnosis efficacy of depression in primary care ambulatory practice	The score between HSCL25 scale and PSE9 questionary will be compared	1 month

Collaborators and Investigators

• Sponsor: University Hospital, Brest
• Investigators: Principal Investigator: Patrice NABBE, GP, GP department

Publications and helpful links

General Publications

• Nabbe P, Le Reste JY, Guillou-Landreat M, Gatineau F, Le Floch B, Montier T, Van Marwijk H, Van Royen P. The French version of the HSCL-25 has now been validated for use in primary care. PLoS One. 2019 Apr 4;14(4):e0214804. doi: 10.1371/journal.pone.0214804. eCollection 2019.

Study record dates

Study Major Dates

• Study Start: June 1, 2015
• Primary Completion (Actual): February 1, 2016
• Study Completion (Actual): October 1, 2016

Study Registration Dates

• First Submitted: March 19, 2015
• First Submitted That Met QC Criteria: April 8, 2015
• First Posted (Estimated): April 13, 2015

Study Record Updates

• Last Update Posted (Estimated): December 3, 2025
• Last Update Submitted That Met QC Criteria: November 26, 2025
• Last Verified: January 1, 2017

More Information

Terms related to this study

• Keywords: Depression; Primary care; General Practitioners
• Additional Relevant MeSH Terms: Behavioral Symptoms; Behavior; Depression
• Other Study ID Numbers: HSCL25 Validation