Postoperative Analgesic Effects of Using Dexmedetomidine for Ultrasound Guided Thoracic Paravertebral Block

August 2, 2016 updated by: Esra Nur Ünalan, TC Erciyes University

Postoperative Analgesic Effects of Using Bupivacaine Alone or Added Dexmedetomidine for Ultrasound Guided Thoracic Paravertebral Block in Thoracotomy

we aimed postoperative analgesic effects of using bupivacaine alone or added dexmedetomidine for ultrasound guided thoracic paravertebral block in thoracotomy

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

paravertebral block is commonly used in the treatment for acute and chronic pain.The duration of paravertebral block could theoretically be prolonged with neurolytic agents. Dexmedetomidine ,an alfa-2 adrenoreceptor agonist, is being used and adjuvant capable of prolonging duration of sensory and motor block on nerve blocks.

Study Type

Interventional

Enrollment (Actual)

93

Phase

  • Phase 4

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Turkey
      • Kayseri, Turkey, 38080
        • Erciyes university medicine faculty

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years to 65 years (Adult, Older Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Description

Inclusion Criteria:

  • ASA 1-2
  • 18-65 aged
  • patient undergoing thoracotomy

Exclusion Criteria:

  • chronic opioid consumption
  • bupivacaine and dexmedetomidine allergies
  • coagulopathy
  • infection at the needle insertion side
  • chronic liver and kidney disease

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Crossover Assignment
  • Masking: Quadruple

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Active Comparator: bupivacaine
0,5% 20 ml bupivacaine added 0.9% 1 ml serum physiologic on paravertebral block
Drug: bupivacaine
21 ml 0.5 %bupivacaine is applied paravertebral space
Other Names:
  • marcaine
Active Comparator: dexmedetomidine
100 mcg dexmedetomidine added to 0,5% 20 ml bupivacaine on paravertebral block
Drug: dexmedetomidin
1 ml dexmedetomidin + 20 ml 0.5 % bupivacaine are applied paravertebral space
Other Names:
  • precedex
Active Comparator: serum phsyologic
0,9% 21 ml serum physiologic
Drug: serum physiologic
21 ml serum physiologic is applied paravertebral space

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
opioid consumption
Time Frame: postoperative 24 hours
patient controlled analgesia
postoperative 24 hours

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
visual analog scale
Time Frame: postoperative 1 day
visual analog scale
postoperative 1 day

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

TC Erciyes University

Investigators

  • Principal Investigator: esra n ünalan, resident, TC Erciyes University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

September 1, 2015

Primary Completion (Actual)

March 1, 2016

Study Completion (Actual)

March 1, 2016

Study Registration Dates

First Submitted

September 7, 2015

First Submitted That Met QC Criteria

September 7, 2015

First Posted (Estimate)

September 9, 2015

Study Record Updates

Last Update Posted (Estimate)

August 3, 2016

Last Update Submitted That Met QC Criteria

August 2, 2016

Last Verified

August 1, 2016

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 2014/649

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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