Contribution LUS in the Diagnosis of Acute Heart Failure (AHF) in Patients Admitted to the ED

Contribution of Pulmonary Ultrasonography in the Diagnosis of Acute Heart Failure (AHF) in Patients Admitted to Emergency Department (ED) for Dyspnea

This study assesses the potential of lung ultrasonography to diagnose heart failure.

Study Overview

• Status: Completed
• Conditions: Dyspnea; Cardiac
• Intervention / Treatment: Diagnostic test: lung ultrasound

Detailed Description

Dyspnea is one of the most distressing situations for the patient . Emergency cases do not always present in conditions that are ideal for immediate diagnosis, which sometimes compromises outcome. Physical examination, laboratory findings and radiography are imperfect, resulting in a need for sophisticated test results that delay management.

Lung ultrasonography is becoming a standard tool in critical cases in the ED.

the investigators aim to perform ultrasonography on consecutive patients admitted to the ICU with dyspnea, comparing lung ultrasonography results on initial presentation with the final diagnosis by the ICU team.

Three items were assessed: artifacts (horizontal A lines or vertical B lines indicating interstitial syndrome), lung sliding, and alveolar consolidation and/or pleural effusion, these items were grouped to assess ultrasound profiles.

This study assesses the potential of lung ultrasonography to diagnose heart failure.

• Study Type: Observational
• Enrollment (Actual): 600

Contacts and Locations

Study Locations

• Tunisia
  • Monastir, Tunisia, 5000
    • Emergency department of university hospital Fattouma Bourguiba of Monastir

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 90 years (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

all patients admitted to the ED with acute dyspnea, with the final diagnosis of heart failure by the ICU team

Description

Inclusion Criteria:

• non traumatic dyspnea with the final diagnosis of heart failure

Exclusion Criteria:

• coma,
• shock,Mechanical Ventilation,
• vasopressor drugs
• arrhythmia serious and sustained,
• non consent

Study Plan

How is the study designed?

Design Details

• Observational Models: Case-Only
• Time Perspectives: Prospective

Number of groups / cohorts

2

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
HF/HFpEF; patients with heart failure with a preserved ejection fraction(HFpEF) perform LUS	Diagnostic test: lung ultrasound; we perform a lung ultrasound to all the patients admitted for dyspnea independantly from the final diagnosis
HF/HFrEF; patients with heart failure with a reduced ejection fraction(HFrEF) perform LUS	Diagnostic test: lung ultrasound; we perform a lung ultrasound to all the patients admitted for dyspnea independantly from the final diagnosis

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
the accuracy of LUS in the diagnosis of heart failure	the accuracy of LUS in the diagnosis of heart failure measured by sensitivity ,specificity, and area under the roc curve	0 days

Collaborators and Investigators

• Sponsor: University of Monastir
• Investigators: Principal Investigator: Nouira Semir, PHD, university Hospital of Monastir

Publications and helpful links

General Publications

• Msolli MA, Sekma A, Marzouk MB, Chaabane W, Bel Haj Ali K, Boukadida L, Bzeouich N, Gannoun I, Trabelssi I, Laaouiti K, Grissa MH, Beltaief K, Dridi Z, Belguith A, Methamem M, Bouida W, Boukef R, Boubaker H, Nouira S; GREAT Network. Bedside lung ultrasonography by emergency department residents as an aid for identifying heart failure in patients with acute dyspnea after a 2-h training course. Ultrasound J. 2021 Feb 9;13(1):5. doi: 10.1186/s13089-021-00207-9.

Helpful Links

• official department website

Study record dates

Study Major Dates

• Study Start (Actual): January 2, 2016
• Primary Completion (Actual): October 1, 2017
• Study Completion (Actual): October 1, 2017

Study Registration Dates

• First Submitted: July 6, 2018
• First Submitted That Met QC Criteria: October 22, 2018
• First Posted (Actual): October 24, 2018

Study Record Updates

• Last Update Posted (Actual): January 16, 2019
• Last Update Submitted That Met QC Criteria: January 15, 2019
• Last Verified: January 1, 2019

More Information

Terms related to this study

• Keywords: heart failure; diagnosis; accuracy; Lung ultrasound,
• Additional Relevant MeSH Terms: Heart Diseases; Cardiovascular Diseases; Respiratory Tract Diseases; Respiration Disorders; Signs and Symptoms, Respiratory; Heart Failure; Dyspnea
• Other Study ID Numbers: Lung Ultra Sound (LUS)

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: Undecided

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No
• product manufactured in and exported from the U.S.: No