Effect of One Minute of Resistance Exercise Per Day on Muscular Strength (The ONE Study)

The ONE Study: Effect of One Minute of Resistance Exercise Per Day on Muscular Strength

This study will evaluate the effect of one minute of resistance exercise per day on muscular strength in adults. Half of the participants will undergo a 12-week home-based resistance exercise programme, while the other half will continue their usual lifestyle behaviour.

Study Overview

• Status: Suspended
• Conditions: Exercise
• Intervention / Treatment: Behavioral: 12-week home-based resistance exercise programme

Detailed Description

A resistance training programme can lead to a variety of health benefits including increases in muscle size and strength. Other potential health benefits of resistance training include reduction of body fat, increased metabolic rate, improve insulin sensitivity, blood glucose tolerance and blood lipid profiles. Meta-analyses indicate that while performing resistance exercise two or more times per week of resistance exercise per muscle group appears to be optimal to maximise strength gains, a single set of resistance exercise per muscle group per week, if performed to failure is sufficient to induce substantial strength changes.

The current physical activity guidelines recommend undertaking muscle strengthening activities involving major muscle groups two days a week or more, as well as undertaking at least 150 minutes per week of moderate intensity physical activity (or 75 minutes per week of vigorous intensity physical activity). However, only small portion of the population achieves the muscle strengthening aspect of the guidelines. As lack of time is often cited as a reason not to engage in physical activity, this study is seeking to investigate a low time-commitment approach to resistance exercise which could increase muscular strength. To address this, the present study will to split a typical single session of resistance exercise involving several exercises across different muscle groups into separate 1-minute micro-sessions where a different muscle group is exercised on each day of the week. The aim is to determine the effects of a one-minute-per-day home-based resistance exercise training on muscular strength.

The study is a randomized control trial in which the control group will continue their lifestyle behaviour and will be asked not to increase their physical activity levels and the exercise group will perform a 12-week home-based resistance exercise programme, involving doing one minute of resistance exercise per day on six days of the week, with a different exercise performed on each day. All participants will be measured at baseline, 4 weeks, 8 weeks and 12 weeks.

• Study Type: Interventional
• Enrollment (Anticipated): 56
• Phase: Not Applicable

Contacts and Locations

Study Locations

• United Kingdom
  • Glasgow, United Kingdom, G12 8TA
    • University of Glasgow

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 65 years (ADULT, OLDER_ADULT)
• Accepts Healthy Volunteers: Yes
• Genders Eligible for Study: All

Description

Inclusion Criteria:

• Aged 18-65 years

Exclusion Criteria:

• Diabetes
• Uncontrolled hypertension (blood pressure > 150/90 on medication).
• History of cardiovascular disease
• Undertaking more than 150 minutes of moderate intensity or 75 minutes of vigorous physical activity or undertaking any resistance exercise.
• Other significant illness that would prevent the participant to undertake physical activity.

Study Plan

How is the study designed?

Design Details

• Primary Purpose: PREVENTION
• Allocation: RANDOMIZED
• Interventional Model: PARALLEL
• Masking: NONE

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
NO_INTERVENTION: Control Group; The control group will be asked to keep their lifestyle behaviour and not increase their physical activity levels during the study period.
EXPERIMENTAL: Exercise Group; The exercise group will engage in a home-based resistance exercise intervention for 12 weeks. They will perform 6 exercises, one each day for one minute, for 6 days a week.	Behavioral: 12-week home-based resistance exercise programme; Participants will perform 6 exercises (press-ups, squats, squat jumps, plank, upright row and seated row) for one minute, aiming for the maximum number of repetitions. Participants will perform one exercise per day, for 6 days a week, for 12 weeks.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Muscle strength	Change in 1-RM (one repetition maximum) (kg) for bench press, leg press and lat pull down (kg).	Change between baseline and 4 weeks
Muscle strength	Change in 1-RM (one repetition maximum) (kg) for bench press, leg press and lat pull down (kg).	Change between baseline and 8 weeks
Muscle strength	Change in 1-RM (one repetition maximum) (kg) for bench press, leg press and lat pull down (kg).	Change between baseline and 12 weeks

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Muscle endurance	Change in maximal number of repetitions with a load of 50% of baseline 1-RM for bench press, leg press and lateral pull down.	Change between baseline and 4 weeks
Muscle endurance	Change in maximal number of repetitions with a load of 50% of baseline 1-RM for bench press, leg press and lateral pull down.	Change between baseline and 8 weeks
Muscle endurance	Change in maximal number of repetitions with a load of 50% of baseline 1-RM for bench press, leg press and lateral pull down.	Change between baseline and 12 weeks
Weight	Change in weight (kg).	Change between baseline and 4 weeks
Weight	Change in weight (kg).	Change between baseline and 8 weeks
Weight	Change in weight (kg).	Change between baseline and 12 weeks
Waist	Change in waist circumference (cm).	Change between baseline and 4 weeks
Waist	Change in waist circumference (cm).	Change between baseline and 8 weeks
Waist	Change in waist circumference (cm).	Change between baseline and 12 weeks
Body composition	Change in fat mass and free fat mass measured by Bioelectrical Impedance Analysis (BIA).	Change between baseline and 4 weeks
Body composition	Change in fat mass and free fat mass measured by Bioelectrical Impedance Analysis (BIA).	Change between baseline and 8 weeks
Body composition	Change in fat mass and free fat mass measured by Bioelectrical Impedance Analysis (BIA).	Change between baseline and 12 weeks
Muscle thickness	Change in muscle thickness of vastus lateralis (mm) measured with ultrasound.	Change between baseline and 12 weeks
Grip strength	Change in grip strength (kg) measured using a hand grip dynamometer	Change between baseline and 4 weeks
Grip strength	Change in grip strength (kg) measured using a hand grip dynamometer	Change between baseline and 8 weeks
Grip strength	Change in grip strength (kg) measured using a hand grip dynamometer	Change between baseline and 12 weeks

Collaborators and Investigators

• Sponsor: University of Glasgow

Study record dates

Study Major Dates

• Study Start (ACTUAL): June 20, 2019
• Primary Completion (ANTICIPATED): October 28, 2021
• Study Completion (ANTICIPATED): December 31, 2021

Study Registration Dates

• First Submitted: June 6, 2019
• First Submitted That Met QC Criteria: June 7, 2019
• First Posted (ACTUAL): June 10, 2019

Study Record Updates

• Last Update Posted (ACTUAL): September 30, 2020
• Last Update Submitted That Met QC Criteria: September 28, 2020
• Last Verified: September 1, 2020

More Information

Terms related to this study

• Keywords: Muscle Strength; Resistance training; Strength Training; voluntary failure
• Other Study ID Numbers: 200180137

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No